Nav: Home

American Society for Investigative Pathology Award presented to David M. Engman

June 04, 2008

Bethesda, MD - The American Society for Investigative Pathology (ASIP) is pleased to announce that David M. Engman, MD, PhD, Professor of Pathology and Microbiology-Immunology at Northwestern University is the 2008 recipient of the ASIP - Amgen Outstanding Investigative Award, a prestigious annual award for excellent research in experimental pathology funded by Amgen. Dr. Engman presented his paper, "Pathogenesis of Chagas Disease: from Trypanosome to Host Cell Invasion to Myocarditis" at the ASIP 2008 Annual Meeting at Experimental Biology in San Diego, where he received the award.

In his research, Dr. Engman has investigated the biology of trypanosomes that cause African sleeping sickness and Chagas Disease. Among other things, Dr. Engman's research involves the mechanism of Chagas disease and creating numerous animal models of the disease, which include the etiology as well as the functional significance of cardiac autoimmunity that is the result of infection. The autoimmune response is made up of two factions: the antigenic molecular mimicry between parasite and heart proteins and cardiac autoimmunity resulting from cardiomyocyte damage by the parasite. By using advanced equipment, the lab is attempting to re-establish immune tolerance to heart antigens while enhancing a robust anti-parasite immune response to clear the organism.

Dr. Engman received his BA from Northwestern University and his MD and PhD from the University of Iowa. Since beginning his career at Northwestern 18 years ago, Dr. Engman has served on many panels concerning the general training of physician-scientists and the specific training of pathologist-scientists, including the National Association of MD/PhD Programs. Dr. Engmen currently serves as the Chair of the AAMC MD/PhD Group and as the Director of the Northwestern Medical Scientist Training Program (MSTP).
-end-
The American Society for Investigative Pathology (ASIP) is a non-profit educational 501(c)3 society of biomedical scientists who investigate the mechanisms of disease. Investigative pathology is an integrative discipline that links the presentation of disease in the whole organism to its fundamental cellular and molecular mechanisms using a variety of structural, functional, and genetic techniques, and ultimately applies research findings to the diagnosis and treatment of diseases. ASIP is a member of the Federation of American Societies for Experimental Biology (FASEB), a coalition of 21 independent societies that plays an active role in lobbying for the interests of 84,000 biomedical scientists. ASIP has three Divisions, The Association for Pathology Informatics (API), the International Society for Biological and Environmental Repositories (ISBER), and the Pulmonary Pathology Society (PPS). For more information visit the ASIP website at www.asip.org.

American Society for Investigative Pathology

Related Chagas Disease Articles:

Deaths from Chagas disease under-reported
Chagas disease, affecting millions of people in Central and South America, is classified as one of the 17 most important neglected diseases by the World Health Organization.
First large-scale survey of Chagas disease in the United States confirms that the 'silent killer' is a major public health challenge for the country
A study of almost 5,000 Latin American-born residents of Los Angeles County found that 1.24 percent tested positive for Chagas disease, a parasitic infection that can cause life-threatening heart damage if not treated early.
Findings support role of vascular disease in development of Alzheimer's disease
Among adults who entered a study more than 25 years ago, an increasing number of midlife vascular risk factors, such as obesity, high blood pressure, diabetes, high cholesterol and smoking, were associated with elevated levels of brain amyloid (protein fragments linked to Alzheimer's disease) later in life, according to a study published by JAMA.
Dietary factors associated with substantial proportion of deaths from heart disease, stroke, and disease
Nearly half of all deaths due to heart disease, stroke, and type 2 diabetes in the US in 2012 were associated with suboptimal consumption of certain dietary factors, according to a study appearing in the March 7 issue of JAMA.
Study links changes in oral microbiome with metabolic disease/risk for dental disease
A team of scientists from The Forsyth Institute and the Dasman Diabetes Institute in Kuwait have found that metabolic diseases, which are characterized by high blood pressure, high blood sugar, and obesity -- leads to changes in oral bacteria and puts people with the disease at a greater risk for poor oral health.
Targets and patented drugs for chemotherapy of Chagas disease
Chagas disease is a parasitic infection typically spread by triatomine vectors, affecting millions of people all over Latin America.
IDRI contributes to first point-of-care Chagas disease diagnostic for US
With Chagas disease becoming more prevalent in the United States, a diagnostic to quickly and easily detect infection is needed.
Seroprevalence and disease burden of chagas disease in south Texas
A paper published in PLOS Neglected Diseases led by researchers at the National School of Tropical Medicine at Baylor College of Medicine suggests that the disease burden in southern Texas is much higher than previously thought.
Fatty liver disease contributes to cardiovascular disease and vice versa
For the first time, researchers have shown that a bi-directional relationship exists between fatty liver disease and cardiovascular disease.
Resveratrol reverses heart damage in mice with Chagas disease
Resveratrol is the antioxidant found in red wine and famous as a food supplement capable of mimicking the effects of exercise and low calorie diets in the heart.

Related Chagas Disease Reading:

Best Science Podcasts 2019

We have hand picked the best science podcasts for 2019. Sit back and enjoy new science podcasts updated daily from your favorite science news services and scientists.
Now Playing: TED Radio Hour

Approaching With Kindness
We often forget to say the words "thank you." But can those two words change how you — and those around you — look at the world? This hour, TED speakers on the power of gratitude and appreciation. Guests include author AJ Jacobs, author and former baseball player Mike Robbins, Dr. Laura Trice, Professor of Management Christine Porath, and former Danish politician Özlem Cekic.
Now Playing: Science for the People

#509 Anisogamy: The Beginning of Male and Female
This week we discuss how the sperm and egg came to be, and how a difference of reproductive interest has led to sexual conflict in bed bugs. We'll be speaking with Dr. Geoff Parker, an evolutionary biologist credited with developing a theory to explain the evolution of two sexes, about anisogamy, sexual reproduction through the fusion of two different gametes: the egg and the sperm. Then we'll speak with Dr. Roberto Pereira, research scientist in urban entomology at the University of Florida, about traumatic insemination in bed bugs.