Stakeholders update newborn screening guidelines for critical congenital heart disease

June 04, 2020

WASHINGTON - (June 4, 2020) - A distinguished panel of medical experts, state and federal health officials, and congenital heart disease parent advocates published recommended updates to the current American Academy of Pediatrics' protocol for detecting critical congenital heart disease (CCHD) in newborn babies using pulse oximetry. The recommendations were released online by the journal Pediatrics. Updates include: "In less than ten years, this non-invasive, low-cost screening tool and algorithm that started as a regional pilot program has become a critical part of the Recommended Uniform Screening Panel (RUSP) for every newborn in the United States," says Gerard Martin, M.D., cardiologist at Children's National Hospital and a lead author of the study recommendations. "We estimate that at least 120 babies' lives are saved by this tool in the U.S. every year, and we think the tool can save even more as it grows to become a standard of newborn care around the world."

Key algorithm changesThe panel considered several additional updates to the U.S. algorithm, but did not feel the evidence was strong enough to warrant further changes at this time.

Uniform public health CCHD reporting and clinician training

Though screening is required in all 50 states, the panel found that data collection is inconsistent across states. This makes it difficult to assess trends in effectiveness and identify any screening gaps on a national scale.

"Every state has done a good job of making sure that newborns are screened in the appropriate window," says Matt Oster, M.D., MPH, director of the Cardiac Outcomes Research Program at Children's Healthcare of Atlanta, and another study author. "However, variations in reporting, including in the definition of critical congenital heart disease make it difficult to know precisely how effective the tool is. It's critical that we help public health programs focus on protocol adherence and standardize data collection so we can accurately gauge the cases we capture and those we miss."

Training for providers; education for parents

The panel also emphasized the importance of making sure every care provider is trained to administer and record results in a uniform way.

As part of the RUSP in the United States, every baby born is required to receive the pulse oximetry screening within the first 24 to 48 hours, along with a battery of other screening tools.

"We need to do a better job of explaining to parents that a failed pulse oximetry screen simply triggers a closer clinical assessment," Dr. Martin says. "It doesn't indicate a specific issue other than a low level of oxygen saturation in the infant's body. Further clinical evaluation will tell us more and help us find any diagnosis."

The future of pulse oximetry to detect CCHD

Pulse oximetry screening continues to grow in the United States and other countries. The panel recommended a continuing effort by organizations such as the AAP, the American College of Cardiology and the American Heart Association to lead implementation of this inexpensive screening tool around the world. In 2014, the World Health Organization estimated that doing so might save more than 750,000 lives by the year 2030.
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About Children's National Hospital

Children's National Hospital, based in Washington, D.C., celebrates 150 years of pediatric care, research and commitment to community. Volunteers opened the hospital in 1870 with 12 beds to care for Civil War orphans. Today, 150 years stronger, it is the nation's No. 6 children's hospital. It is ranked No. 1 for newborn care for the third straight year and ranked in all specialties evaluated by U.S. News & World Report. Children's National is transforming pediatric medicine for all children. In 2020, construction will be complete on the Children's National Research and Innovation Campus, the first in the nation dedicated to pediatric research. Children's National has been designated twice as a Magnet® hospital, demonstrating the highest standards of nursing and patient care delivery. This pediatric academic health system offers expert care through a convenient, community-based primary care network and specialty outpatient centers in the D.C., metropolitan area, including the Maryland and Northern Virginia suburbs. Children's National is home to the Children's National Research Institute and Sheikh Zayed Institute for Pediatric Surgical Innovation and is the nation's seventh-highest NIH-funded children's hospital. It is recognized for its expertise and innovation in pediatric care and as a strong voice for children through advocacy at the local, regional and national levels.

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Children's National Hospital

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