Physical activity in all of its forms may help maintain muscle mass in midlife

June 08, 2020

A large study of middle-aged women shows that age-related changes in skeletal muscle are part of everyday life for women in their fifties. During this time, women transition from perimenopause to postmenopause and the production of estrogen ceases. Loss of estrogen has an effect on muscles and leads to a decline in muscle mass. Physical activity in all of its forms may help maintain muscle mass in midlife.

"We already knew that estrogen has a role in the regulation of muscle properties," says doctoral student Hanna-Kaarina Juppi. "By following the hormonal status, measuring many aspects of muscles and by taking into consideration the simultaneous chronological aging of women going through menopausal transition, we were able to show that the decrease of muscle mass takes place already in early postmenopause."

In the current study, muscle size was measured in the perimenopausal state and right after entering postmenopause, when menstruation had permanently stopped. Women were on average 51-and-a-half years old at the beginning of the study and 53 years old at the final measurements, so the average duration of menopausal transition was one-and-a-half years. The time it takes a woman to go through menopause is unique: in this study it varied from less than six months to more than three years. During this time, the decrease in muscle mass was on average one percent.

Juppi continues: "The observed change does not seem like much, but what is meaningful is that the decline happens in a short period of time and can have an impact on metabolism, as muscles are important regulators of whole-body metabolism."

Physical activity was found to be positively associated with the maintenance of muscle mass during the menopausal transition. Women who were more active had higher muscle mass before and after menopause compared to the less active women. It seems that even though menopause alone decreases muscle mass, staying physically active throughout middle age can help women to slow the change.

The current study was conducted in the Gerontology Research Center and Faculty of Sport and Health Sciences, and is part of a larger study, Estrogenic Regulation of Muscle Apoptosis (ERMA), led by Academy Research Fellow Eija Laakkonen. More than a thousand women between the ages of 47 and 55 from the Jyväskylä region participated in the ERMA study. At the beginning of the study, 381 of them were perimenopausal, while 234 reached early postmenopause during the study. The research was funded by the Academy of Finland and the European Commission.
-end-


University of Jyväskylä - Jyväskylän yliopisto

Related Physical Activity Articles from Brightsurf:

Physical activity in the morning could be most beneficial against cancer
The time of day when we exercise could affect the risk of cancer due to circadian disruption, according to a new study with about 3,000 Spanish people  

Physical activity and sleep in adults with arthritis
A new study published in Arthritis Care & Research has examined patterns of 24-hour physical activity and sleep among patients with rheumatoid arthritis, lupus, and knee osteoarthritis.

Regular physical activity seems to enhance cognition in children who need it most
Researchers at the Universities of Tsukuba and Kobe re-analyzed data from three experiments that tested whether physical activity interventions lead to improved cognitive skills in children.

The benefits of physical activity for older adults
New findings published in the Scandinavian Journal of Medicine & Science in Sports reveal how physically active older adults benefit from reduced risks of early death, breast and prostate cancer, fractures, recurrent falls, functional limitations, cognitive decline, dementia, Alzheimer's disease, and depression.

Physical activity may protect against new episodes of depression
Increased levels of physical activity can significantly reduce the odds of depression, even among people who are genetically predisposed to the condition.

Is physical activity always good for the heart?
Physical activity is thought to be our greatest ally in the fight against cardiovascular disease.

Physical activity in lessons improves students' attainment
Students who take part in physical exercises like star jumps or running on the spot during school lessons do better in tests than peers who stick to sedentary learning, according to a UCL-led study.

Physical activity may attenuate menopause-associated atherogenic changes
Leisure-time physical activity is associated with a healthier blood lipid profile in menopausal women, but it doesn't seem to entirely offset the unfavorable lipid profile changes associated with the menopausal transition.

Are US adults meeting physical activity guidelines?
The proportion of US adults adhering to the 'Physical Activity Guidelines for Americans' from the US Department of Health and Human Services didn't significantly improve between 2007 and 2016 but time spent sitting increased.

Children from disadvantaged backgrounds do less vigorous physical activity
Children from disadvantaged backgrounds and certain ethnic minority backgrounds, including from Pakistani and Bangladeshi backgrounds, have lower levels of vigorous physical activity, according to researchers at the University of Cambridge.

Read More: Physical Activity News and Physical Activity Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.