Are blood donor sex, pregnancy history and death of transfusion recipients associated?

June 11, 2019

Bottom Line: Whether blood donors' sex and pregnancy history were associated with death for red blood cell transfusion recipients was investigated in this study that analyzed data from three study groups totaling more than 1 million transfusion recipients. There were no statistically significant associations between any of the three donor characteristics studied (female donors, previously pregnant donors, and donors and recipients who were of opposite sex) with in-hospital mortality of transfusion recipients in any of the three study groups. Prior research has produced conflicting results about possible associations between red blood cells from female donors and increased risk of death for transfusion recipients. The study has several limitations, including its observational design which can only show associations.

Authors: Gustaf Edgren, M.D., Ph.D., Karolinska Institutet, Stockholm, Sweden, and coauthors

(doi:10.1001/jama.2019.7084)

Editor's Note: The article contains conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.
-end-
Embed this link to provide your readers free access to the full-text article: This link will be live at the embargo time: https://jamanetwork.com/journals/jama/fullarticle/2735501?guestAccessKey=dbd8ae43-82a7-4b63-9cba-cdc7ff4aa291?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=061119

JAMA

Related Death Articles from Brightsurf:

Recommendations to improve consensus of determining brain death, death by neurologic criteria
International professional societies developed recommendations for minimum clinical standards to determine brain death/death by neurologic criteria in adults and children to improve the consistency of these criteria within and among countries.

Silicones may lead to cell death
Silicone molecules from breast implants can initiate processes in human cells that lead to cell death.

Sleep, death and ... the gut?
A new study finds a causal link between sleep deprivation and death.

Risk of death from stroke falls by 24%
Thousands more patients each year are surviving strokes, as the risk of death and disability after a stroke fell significantly between 2000 and 2015, according to analysis by Guy's and St Thomas' researchers.

Cells control their dance of death
La Trobe University researchers have revealed for the first time how white blood cells control the final moments of their death, helping their own removal from the human body.

Predicting frailty, disability and death
In a study led by investigators from Brigham and Women's Hospital, researchers analyzed patterns of movement among elderly study participants and found that irregular, spontaneous fluctuations could predict a person's risk of frailty, disability and death years later.

One in 10 people have 'near-death' experiences, according to new study
The new findings were presented at the 5th European Academy of Neurology (EAN) Congress.

Jobs vs. death toll: Calculating corporate death penalties
What misdeeds warrant corporate death penalties? A new study explores two case studies focused on industries that kill more people than they employ.

New role for death molecule
To unravel programmed cell death pathways, investigators examine a molecule deemed unimportant, and find new function.

Death near the shoreline, not life on land
Our understanding of when the very first animals started living on land is helped by identifying trace fossils--the tracks and trails left by ancient animals--in sedimentary rocks that were deposited on the continents.

Read More: Death News and Death Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.