Nav: Home

Camelina sativa oil and fatty fish have positive effects on lipid metabolism

June 11, 2020

Camelina sativa oil and fatty fish are rich in polyunsaturated omega-3 fatty acids, but their health benefits seem to differ. A new study from the University of Eastern Finland shows that Camelina sativa oil reduces the formation of fatty acid derivatives that may be harmful to cardiovascular health. Camelina sativa oil also seems to protect against oxidative stress. Fatty fish, on the other hand, increases the circulatory concentration of fatty acid derivatives that alleviate inflammation.

The study, conducted in collaboration between the University of Eastern Finland and Karolinska Institutet in Sweden, examined the associations of fatty and low-fat fish, and Camelina sativa oil, with lipid metabolism and low-grade inflammation. The study lasted for 12 weeks and it involved 79 men and women between 43 and 72 years of age and with impaired fasting glucose. The study participants were divided into four groups. One group replaced fats in their daily diet with Camelina sativa oil and reduced their intake of fish to one serving a week. Two of the groups ate fish four times a week: two servings of fatty fish, such as salmon or vendace, and two servings of low-fat fish, such as saithe or pike. The fourth group was a control group.

A high intake of omega-3 fatty acids from Camelina sativa oil and fatty fish reduced the circulatory proportions of arachidonic acid, which is a long-chain omega-6 fatty acid. Those using Camelina sativa oil also had lower concentrations of mediators derived from arachidonic acid, which may be harmful to cardiovascular health. Moreover, the intake of fatty fish increased the circulatory concentration of fatty acid derivatives that alleviate inflammation.

"Camelina sativa oil and fatty fish had a major effect on lipid metabolism. Our study shows that dietary fats can be used to target metabolic pathways that are linked to cardiovascular diseases and type 2 diabetes," Early Stage Researcher Topi Meuronen, the lead author of the article, from the University of Eastern Finland says.

In addition to its other beneficial effects, Camelina sativa oil was also observed to reduce the circulatory concentration of markers that are indicative of oxidative stress. Low-fat fish, however, did not have an effect on the metabolic pathways studied.

In addition to measuring traditional fatty acid concentrations from blood, the researchers were also interested in changes that occur in fatty acid metabolites, which serve as mediators. An examination of fatty acid metabolism on this level makes it possible to study the effects of dietary polyunsaturated fatty acid in more detail than before. These new results are promising and they support earlier findings on the health benefits of fatty fish. However, further research into fatty acid derived mediators, and especially into the effects of Camelina sativa oil's metabolites, is needed.
For further information, please contact:

Early Stage Researcher Topi Meuronen, University of Eastern Finland, Institute of Public Health and Clinical Nutrition, topi.meuronen(at) '

Research article:

Topi Meuronen, Maria A. Lankinen, Alexander Fauland, Bun-ichi Shimizu, Vanessa D. de Mello, David E. Laaksonen, Craig E. Wheelock, Arja T. Erkkilä & Ursula S. Schwab. Intake of Camelina Sativa Oil and Fatty Fish Alter the Plasma Lipid Mediator Profile in Subjects with Impaired Glucose Metabolism - A Randomized Controlled Trial. Prostaglandins, Leukotrienes & Essential Fatty Acids 159 (2020) 102143.

University of Eastern Finland

Related Cardiovascular Health Articles:

Researchers find cardiovascular health similarities between chimpanzees, humans
Doctors like to remind patients not to monkey around with their health, suggesting that a good diet and regular exercise improve longevity.
A healthy lifestyle for cardiovascular health also promotes good eye health
In a new study, investigators found that ideal cardiovascular health, which is indicative of a healthy lifestyle, was associated with lower odds for ocular diseases especially diabetic retinopathy.
High-deductible health plans and major cardiovascular outcomes
In the first study to examine the association between high out-of-pocket costs and adverse cardiovascular events, research led by the Harvard Pilgrim Health Care Institute finds that individuals with cardiovascular disease risk factors who switched to high-deductible health plans (HDHPs) did not experience increased risk of heart attack or stroke.
Genes and cardiovascular health both affect dementia risk: BU study
A new Boston University School of Public Health (BUSPH) and School of Medicine (BUSM) study finds that genes and cardiovascular health can both raise or lower risk of dementia.
Genes, cardiovascular health each factor into dementia risk
Genes and cardiovascular health both contribute to the risk of dementia, a new study shows.
Housing conditions affect cardiovascular health risks
Lack of stable housing or inadequate housing is related to high blood pressure, obesity and other risk factors for cardiovascular events such as heart attacks, strokes, heart failure and others.
New measure of social determinants of health may improve cardiovascular health assessment
The authors of this study developed a single risk score derived from multiple social determinants of health that predicts county-level cardiovascular disease mortality.
Dietary counselling introduced in infancy leads to better cardiovascular health in adults
The Special Turku Coronary Risk Factor Intervention Project investigated the long-term effects of dietary counselling on cardiovascular health.
Past your bedtime? Inconsistency may increase risk to cardiovascular health
Researchers at Notre Dame found that individuals going to bed even 30 minutes later than their usual bedtime presented a significantly higher resting heart rate that lasted into the following day.
Improving cardiovascular health of the most vulnerable
A two-year pilot project led by Rick Stouffer, MD, shows how the cardiovascular health of the most vulnerable patients can be improved with free medications.
More Cardiovascular Health News and Cardiovascular Health Current Events

Trending Science News

Current Coronavirus (COVID-19) News

Top Science Podcasts

We have hand picked the top science podcasts of 2020.
Now Playing: TED Radio Hour

Listen Again: The Power Of Spaces
How do spaces shape the human experience? In what ways do our rooms, homes, and buildings give us meaning and purpose? This hour, TED speakers explore the power of the spaces we make and inhabit. Guests include architect Michael Murphy, musician David Byrne, artist Es Devlin, and architect Siamak Hariri.
Now Playing: Science for the People

#576 Science Communication in Creative Places
When you think of science communication, you might think of TED talks or museum talks or video talks, or... people giving lectures. It's a lot of people talking. But there's more to sci comm than that. This week host Bethany Brookshire talks to three people who have looked at science communication in places you might not expect it. We'll speak with Mauna Dasari, a graduate student at Notre Dame, about making mammals into a March Madness match. We'll talk with Sarah Garner, director of the Pathologists Assistant Program at Tulane University School of Medicine, who takes pathology instruction out of...
Now Playing: Radiolab

What If?
There's plenty of speculation about what Donald Trump might do in the wake of the election. Would he dispute the results if he loses? Would he simply refuse to leave office, or even try to use the military to maintain control? Last summer, Rosa Brooks got together a team of experts and political operatives from both sides of the aisle to ask a slightly different question. Rather than arguing about whether he'd do those things, they dug into what exactly would happen if he did. Part war game part choose your own adventure, Rosa's Transition Integrity Project doesn't give us any predictions, and it isn't a referendum on Trump. Instead, it's a deeply illuminating stress test on our laws, our institutions, and on the commitment to democracy written into the constitution. This episode was reported by Bethel Habte, with help from Tracie Hunte, and produced by Bethel Habte. Jeremy Bloom provided original music. Support Radiolab by becoming a member today at     You can read The Transition Integrity Project's report here.