Nav: Home

Status epilepticus: An overview

June 12, 2017

Seizures can be divided into three major groups: focal, generalised and unknown. Among all form of seizures, status epilepticus (SE) is a serious neurological condition affecting 50 million people around the world. SE is a neurologic emergency wherein an individual suffers from continuous or repetitive seizures in the brain, each lasting five minutes or more without regaining consciousness between seizures. In these conditions, immediate and effective treatment is required in the least possible time as it is associated with neuronal damage, systemic complications, substantial morbidity and mortality depending on status type, duration, age and etiology.

In this article we give overview and up-to-date information on the latest ILAE classification of epilepsy seizures and potential underlying etiologies triggering SE. We discuss in brief regarding the etiology, diagnostic work-up and prognosis for patients with convulsive, nonconvulsive SE. We have also focussed on the various available anticonvulsant drug therapies and management guidelines in hospital and out of hospital settings, which are used and followed by the neurologists, clinicians and emergency personnel in the emergency room all around the world. All the information collected was consolidated as a treatment algorithm based on the guidelines prescribed and followed by medical agencies around the world. In this paper we explain the presently known potential routes of administration for antiepileptic drugs (AEDs) and their elimination. Many prescriptions around the world mix up AEDs with both enzyme inducing and enzyme inhibition drugs. So to give readers a clear idea, we have written a separate section about this topic and discussed about mechanism and interactions of these drugs in brief. Finally, we conclude our paper with a discussion regarding the current issues in SE treatment and patient recovery strategies after each type of therapy.
-end-
For more information about the article, please visit http://www.eurekaselect.com/149032/article

Bentham Science Publishers

Related Seizures Articles:

Seizures follow similar path regardless of speed, says study
In a new study in Cell Reports, researchers at Columbia University show that the neurons of mice undergoing seizures fire off in a sequential pattern no matter how quickly the seizure propagates -- a finding that confirms seizures are not the result of neurons randomly going haywire.
Study could help explain link between seizures and psychiatric disorders
In a new study published in Cell Reports, scientists at the Gladstone Institutes identified different types of neurons in a brain region called the reticular thalamus.
Pinpointing where seizures are coming from, by looking between the seizures
A computational approach developed at Boston Children's Hospital, described in the journal Neurosurgery, published online May 2, 2017, could enable more patients with epilepsy to benefit from surgery when medications do not help.
'Silent seizures' discovered in patients with Alzheimer's disease
Deep in the brains of two patients with Alzheimer's disease, the main memory structure, the hippocampus, displays episodic seizure-like electrical activity.
Epilepsy -- why do seizures sometimes continue after surgery?
New research from the University of Liverpool, published in the journal Brain, has highlighted the potential reasons why many patients with severe epilepsy still continue to experience seizures even after surgery.
The heart-brain connection: The link between LQTS and seizures
Patients carrying certain mutations that cause Long QT Syndrome, a rare cardiac rhythm disorder, have an increased risk for developing seizures and have more severe cardiac symptoms.
Breast cancer drug found to reduce seizures
A class of drug that inhibits estrogen production and is used to treat breast cancer has been found to quickly and effectively suppress dangerous brain seizures, according to a new Northwestern University study.
Study suggests new treatment for seizures
Researchers from Northwestern University, Evanston, Ill., have discovered a new factor in the escalation of seizures: the synthesis, or generation, of estrogens in the brain.
Minisensor is designed to warn of epileptic seizures
For epilepsy patients and attending physicians, it has been a challenge to correctly assess the frequency and severity of epileptic seizures without inpatient recording equipment.
Many stroke survivors may develop seizures
A substantial proportion of stroke survivors develop seizures in the years following their strokes, according to research presented at the American Stroke Association's International Stroke Conference 2016.

Related Seizures Reading:

Best Science Podcasts 2019

We have hand picked the best science podcasts for 2019. Sit back and enjoy new science podcasts updated daily from your favorite science news services and scientists.
Now Playing: TED Radio Hour

Anthropomorphic
Do animals grieve? Do they have language or consciousness? For a long time, scientists resisted the urge to look for human qualities in animals. This hour, TED speakers explore how that is changing. Guests include biological anthropologist Barbara King, dolphin researcher Denise Herzing, primatologist Frans de Waal, and ecologist Carl Safina.
Now Playing: Science for the People

#SB2 2019 Science Birthday Minisode: Mary Golda Ross
Our second annual Science Birthday is here, and this year we celebrate the wonderful Mary Golda Ross, born 9 August 1908. She died in 2008 at age 99, but left a lasting mark on the science of rocketry and space exploration as an early woman in engineering, and one of the first Native Americans in engineering. Join Rachelle and Bethany for this very special birthday minisode celebrating Mary and her achievements. Thanks to our Patreons who make this show possible! Read more about Mary G. Ross: Interview with Mary Ross on Lash Publications International, by Laurel Sheppard Meet Mary Golda...