Nav: Home

Promising treatment for shoulder pain in wheelchair users with spinal cord injury

June 12, 2019

East Hanover, NJ. June 12, 2019. A New Jersey team of researchers has reported the successful, long-term relief of chronic refractory shoulder pain in a wheelchair user with spinal cord injury (SCI) following a single injection of autologous, micro-fragmented adipose tissue into the affected shoulder joint. The article, "Autologous micro-fragmented adipose tissue as a treatment for chronic shoulder pain in a wheelchair using individual with spinal cord injury: a case report" (doi: 10.1038/s41394-019-0186-8) was epublished ahead of print on May 13, 2019 by Spinal Cord Series and Cases. This is the first reported use of this intervention for shoulder pain in an individual with spinal cord injury who has failed to improve with conservative care, such as physical therapy and pharmacological agents.

The authors are Chris Cherian, MD, of Rutgers New Jersey Medical School, Gerard Malanga, MD, of the New Jersey Regenerative Institute and Kessler Institute for Rehabilitation, Trevor Dyson-Hudson, MD, and Nathan Hogaboom, PhD, of Kessler Foundation, and Michael A. Pollack, MD, of Montclair Radiology.

Courtesy of the publisher, this Editors' Choice article is Open Access through June 30: https://www.nature.com/articles/s41394-019-0186-8

Chronic shoulder pain is a common cause of functional decline among wheelchair users with SCI who rely on their upper limbs for mobility and everyday activities of daily living. When pain persists despite conservative management, current options for individuals with SCI have significant drawbacks. Corticosteroid injections offer only temporary relief and surgical interventions often require prolonged periods of recovery and have poor outcomes, which can add to the burden of disability.

This individual, a 54-year-old man with a ten-year history of T10 complete SCI, had a history of chronic shoulder pain that was unresponsive to conservative treatment, including repeated corticosteroid injections that provided only short-term pain relief of 3 months. Ultrasound and MRI examinations of the shoulder revealed a rotator cuff tear and degenerative changes of the acromioclavicular joint. The participant's own fat was harvested and processed using the Lipogems® system to yield a sample of autologous, micro-fragmented adipose tissue that was injected into the shoulder joint under ultrasound guidance. He experienced relief of pain and improvement in performing activities of daily living. At 12-month follow-up, he remained pain free and maintained his functional improvements, with 50% healing of the rotator cuff tear on MRI.

Treatment of intractable shoulder pain with autologous micro-fragmented adipose tissue warrants further investigation as a potential alternative to surgery in wheelchair users with spinal cord injury.

This report is part of a pilot study at Kessler Foundation funded by the Derfner Foundation. The team also recently received a grant from the New Jersey Commission on Spinal Cord Research to conduct a randomized, controlled trial to investigate the safety and efficacy of micro-fragmented adipose tissue for refractory shoulder pain in wheelchair users with SCI.
-end-
About Kessler Foundation

Kessler Foundation, a major nonprofit organization in the field of disability, is a global leader in rehabilitation research that improves cognition, mobility and long-term outcomes, including employment, for people with neurological disabilities caused by diseases and injuries of the brain and spinal cord. Kessler Foundation leads the nation in funding innovative programs that expand opportunities for employment for people with disabilities.

For more information on Kessler Foundation's research, visit KesslerFoundation.org.

Facebook |http://www.facebook.com/KesslerFoundation

Twitter | http://twitter.com/KesslerFdn

Instagram | https://www.instagram.com/kesslerfdn

YouTube | http://www.youtube.com/user/KesslerFoundation

iTunes & SoundCloud | http://www.soundcloud.com/kesslerfoundation

Contacts:

Carolann Murphy, PA
Senior Staff Writer
973.324.8382
CMurphy@KesslerFoundation.org

Rob Gerth
Director, Communications
973.323.3675
Rgerth@KesslerFoundation.org

Kessler Foundation

Related Spinal Cord Injury Articles:

From spinal cord injury to recovery
Spinal cord injury disconnects communication between the brain and the spinal cord, disrupting control over part of the body.
Transplanting adult spinal cord tissues: A new strategy of repair spinal cord injury
Spinal cord injury repair is one of the most challenging medical problems, and no effective therapeutic methods has been developed.
Timing could mean everything after spinal cord injury
Moderate damage to the thoracic spinal cord causes widespread disruption to the timing of the body's daily activities, according to a study of male and female rats published in eNeuro.
New approach could jumpstart breathing after spinal cord injury
A research team at the Krembil Research Institute in Toronto has developed an innovative strategy that could help to restore breathing following traumatic spinal cord injury.
Gene signature predicts outcome after spinal cord injury
Scientists have determined a gene signature that is linked to the severity of spinal cord injury in animals and humans, according to a study in the open-access journal eLife.
More Spinal Cord Injury News and Spinal Cord Injury Current Events

Best Science Podcasts 2019

We have hand picked the best science podcasts for 2019. Sit back and enjoy new science podcasts updated daily from your favorite science news services and scientists.
Now Playing: TED Radio Hour

Rethinking Anger
Anger is universal and complex: it can be quiet, festering, justified, vengeful, and destructive. This hour, TED speakers explore the many sides of anger, why we need it, and who's allowed to feel it. Guests include psychologists Ryan Martin and Russell Kolts, writer Soraya Chemaly, former talk radio host Lisa Fritsch, and business professor Dan Moshavi.
Now Playing: Science for the People

#537 Science Journalism, Hold the Hype
Everyone's seen a piece of science getting over-exaggerated in the media. Most people would be quick to blame journalists and big media for getting in wrong. In many cases, you'd be right. But there's other sources of hype in science journalism. and one of them can be found in the humble, and little-known press release. We're talking with Chris Chambers about doing science about science journalism, and where the hype creeps in. Related links: The association between exaggeration in health related science news and academic press releases: retrospective observational study Claims of causality in health news: a randomised trial This...