MSU lands $2.1 million grant to take part in national autism study

June 19, 2009

EAST LANSING, Mich. -- Michigan State University has been awarded a three-year, $2.1 million federal grant to serve as the data coordinating center for the largest epidemiological study ever on autism.

MSU's Biomedical Research Informatics Core, established in 2001 and now part of the university's Clinical and Translational Science Institute, will collect and create a repository for data from nearly 3,000 families as part of the congressionally mandated Study to Explore Early Development.

"Autism is a serious disabling condition that has been estimated to occur in one in 150 children in the United States," said Phil Reed, director of MSU's BRIC and the principal investigator for the grant. "Our work with the Centers for Disease Control supports the largest study ever conducted designed to help identify factors that may put children at risk for the disease.

"For a study of this magnitude, it is vital to have strong data coordination and data security. We are pleased the CDC recognizes our center's capabilities."

The 10-year SEED study will help identify what might put children at risk for autism spectrum disorders and other developmental disabilities. Six study sites and MSU's role as the data coordinating center make up the Centers for Autism and Developmental Disabilities Research and Epidemiology Network. The network was a result of the passage of the federal Children's Health Act of 2000. The study sites are in California, Colorado, Maryland, North Carolina, Pennsylvania and at the CDC's headquarters in Atlanta.

The study is looking at three main areas: The causes of autism, a brain development disorder often affecting children before their third birthday, are not known. A large study such as this will give doctors and researchers a base of knowledge to draw on as they seeks ways to prevent and treat the condition, said Nigel Paneth, an MSU epidemiologist and co-investigator in the study.

"It is very exciting for MSU to play such a key role in the national effort to try to find the causes of autism," Paneth said.

BRIC's role includes using a Web-based data collection system created in 2005 that allows investigators to input and analyze information in real-time.

"To enable us to do this, we have built a sophisticated Internet-based system for data collection and are developing additional technical innovations in data management to handle the 100 million data elements anticipated in this study," Reed said.
-end-
For more information on the study, visit http://www.cdc.gov/ncbddd/autism/caddre.htm.

Michigan State University has been advancing knowledge and transforming lives through innovative teaching, research and outreach for more than 150 years. MSU is known internationally as a major public university with global reach and extraordinary impact. Its 17 degree-granting colleges attract scholars worldwide who are interested in combining education with practical problem solving.

For MSU news on the Web, go to news.msu.edu.

Michigan State University

Related Autism Articles from Brightsurf:

Autism-cholesterol link
Study identifies genetic link between cholesterol alterations and autism.

National Autism Indicators Report: the connection between autism and financial hardship
A.J. Drexel Autism Institute released the 2020 National Autism Indicators Report highlighting the financial challenges facing households of children with autism spectrum disorder (ASD), including higher levels of poverty, material hardship and medical expenses.

Autism risk estimated at 3 to 5% for children whose parents have a sibling with autism
Roughly 3 to 5% of children with an aunt or uncle with autism spectrum disorder (ASD) can also be expected to have ASD, compared to about 1.5% of children in the general population, according to a study funded by the National Institutes of Health.

Adulthood with autism
The independence that comes with growing up can be scary for any teenager, but for young adults with autism spectrum disorder and their caregivers, the transition from adolescence to adulthood can seem particularly daunting.

Brain protein mutation from child with autism causes autism-like behavioral change in mice
A de novo gene mutation that encodes a brain protein in a child with autism has been placed into the brains of mice.

Autism and theory of mind
Theory of mind, or the ability to represent other people's minds as distinct from one's own, can be difficult for people with autism.

Potential biomarker for autism
A study of young children with autism spectrum disorder published in JNeurosci reveals altered brain waves compared to typically developing children during a motor control task.

Autism often associated with multiple new mutations
Most autism cases are in families with no previous history of the disorder.

State laws requiring autism coverage by private insurers led to increases in autism care
A new study led by researchers at the Johns Hopkins Bloomberg School of Public Health has found that the enactment of state laws mandating coverage of autism spectrum disorder (ASD) was followed by sizable increases in insurer-covered ASD care and associated spending.

Autism's gender patterns
Having one child with autism is a well-known risk factor for having another one with the same disorder, but whether and how a sibling's gender influences this risk has remained largely unknown.

Read More: Autism News and Autism Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.