New 'nicotine vaccine' treatment to be tested in Madison

June 20, 2006

MADISON - An innovative new approach to treating tobacco addiction - an experimental nicotine vaccine - will be tested in Madison starting this month.

The treatment is designed to gradually reduce the amount of nicotine that gets to the brain, making cigarettes less addictive. The University of Wisconsin-Madison's Center for Tobacco Research and Intervention (UW-CTRI) in the School of Medicine and Public Health is recruiting approximately 40 current smokers to volunteer for this research study. Smokers who volunteer and qualify for this study will receive quit-smoking counseling and may receive medication at no cost.

Likely participants are daily smokers at least 18 years of age, in good health and willing to follow the treatment procedures. Participants in the study will be asked to make up to 24 clinic visits during a year.

"We are pleased to have been selected to test an experimental nicotine vaccine - a potentially important advance in treating tobacco addiction," says Michael Fiore, UW-CTRI director. "In this study, we will examine how the vaccine can help smokers break free of their dependence on tobacco - by reducing the effects of nicotine on the brain."

Participants will also receive payment to cover the time and transportation and/or parking for the clinic visits. Individuals who would like to volunteer for the study should call (877) END-CIGS or visit

Every year 300,000 Wisconsin residents try to quit smoking. Most try to quit "cold turkey." Only one in 20 succeed. Most smokers make several quit attempts before they successfully quit.

Tobacco use is the No. 1 cause of preventable disease and death in America. More than 400,000 Americans and more than 7,000 Wisconsin residents die each year of illnesses caused by smoking. More than 70 percent of current adult smokers have stated that they want to quit smoking.
The Center for Tobacco Research and Intervention has provided cessation and prevention services in Wisconsin since 1992 and is a nationally recognized research center.

CONTACT: Gloria Meyer, (608) 265-4447,

University of Wisconsin-Madison

Related Smoking Articles from Brightsurf:

Smoking rates falling in adults, but stroke survivors' smoking rates remain steady
While the rate of Americans who smoke tobacco has fallen steadily over the last two decades, the rate of stroke survivors who smoke has not changed significantly.

What is your risk from smoking? Your network knows!
A new study from researchers at Penn's Annenberg School for Communication found that most people, smokers and non-smokers alike, were nowhere near accurate in their answers to questions about smoking's health effects.

Want to quit smoking? Partner up
Kicking the habit works best in pairs. That's the main message of a study presented today at EuroPrevent 2019, a scientific congress of the European Society of Cardiology (ESC).

Smoking and mortality in Asia
In this analysis of data from 20 studies conducted in China, Japan, South Korea, Singapore, Taiwan and India with more than 1 million participants, deaths associated with smoking continued to increase among men in Asia grouped by the years in which they were born.

Predictors of successfully quitting smoking among smokers registered at the quit smoking clinic at a public hospital in northeastern Malaysia
In the current issue of Family Medicine and Community Health, Nur Izzati Mohammad et al. consider how cigarette smoking is one of the risk factors leading to noncommunicable diseases such as cardiovascular and respiratory system diseases and cancer.

Restaurant and bar smoking bans do reduce smoking, especially among the highly educated
Smoking risk drops significantly in college graduates when they live near areas that have completely banned smoking in bars and restaurants, according to a new study in the American Journal of Epidemiology.

How the UK smoking ban increased wellbeing
Married women with children reported the largest increase in well-being following the smoking bans in the UK in 2006 and 2007 but there was no comparable increase for married men with children.

Smoking study personalizes treatment
A simple blood test is allowing Vanderbilt University Medical Center (VUMC) researchers to determine which patients should be prescribed varenicline (Chantix) to stop smoking and which patients could do just as well, and avoid side effects, by using a nicotine patch.

A biophysical smoking gun
While much about Alzheimer's disease remains a mystery, scientists do know that part of the disease's progression involves a normal protein called tau, aggregating to form ropelike inclusions within brain cells that eventually strangle the neurons.

A case where smoking helped
A mutation in the hemoglobin of a young woman in Germany was found to cause her mild anemia.

Read More: Smoking News and Smoking Current Events is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to