Heartburn common in western populations

June 22, 2006

In western countries, 25% of people report having heartburn at least once a month, 12% at least once per week, and 5% describe daily symptoms, state the authors of a Seminar in this week's issue of The Lancet.

Heartburn results from gastro-oesophageal reflux disease (GORD), where the contents of the stomach are pushed up into the oesophagus. Heartburn is more common in western populations than in non-western populations, write Nicholas Talley (Mayo Clinic College of Medicine, Rochester, MN, USA) and colleagues in their Seminar. In east Asian populations, for example, the prevalence is much lower than in western populations, with 11% reporting heartburn at least once per month, 4% weekly, and 2% having daily symptoms. The cause of the disease is currently unknown but genetic factors are likely to be important, state the authors. Lifestyle factors, such as obesity and smoking, may also increase a person's risk of developing GORD.

Professor Talley states: "Gastro-oesophageal reflux disease is a common problem and is expensive to manage in both primary and secondary care settings. The annual direct cost for managing the disease is estimated to be more than $9 billion dollars in the USA."
-end-
Contact: Professor Nicholas J Talley, Mayo Clinic College of Medicine, Division of Gastroenterology and Hepatology, Motility Interest Group, PL 6-65, 200 First Street SW, Rochester, MN 55905, USA. T) 1-507-266-1989 Talley.Nicholas@mayo.edu

Lancet

Related Disease Articles from Brightsurf:

CLCN6 identified as disease gene for a severe form of lysosomal neurodegenerative disease
A mutation in the CLCN6 gene is associated with a novel, particularly severe neurodegenerative disorder.

Cellular pathway of genetic heart disease similar to neurodegenerative disease
Research on a genetic heart disease has uncovered a new and unexpected mechanism for heart failure.

Mechanism linking gum disease to heart disease, other inflammatory conditions discovered
The link between periodontal (gum) disease and other inflammatory conditions such as heart disease and diabetes has long been established, but the mechanism behind that association has, until now, remained a mystery.

Potential link for Alzheimer's disease and common brain disease that mimics its symptoms
A new study by investigators from Brigham and Women's Hospital uncovered a group of closely related genes that may capture molecular links between Alzheimer's disease and Limbic-predominant Age-related TDP-43 Encephalopathy, or LATE, a recently recognized common brain disorder that can mimic Alzheimer's symptoms.

Antioxidant agent may prevent chronic kidney disease and Parkinson's disease
Researchers from Osaka University developed a novel dietary silicon-based antioxidant agent with renoprotective and neuroprotective effects.

Tools used to study human disease reveal coral disease risk factors
In a study published in Scientific Reports, a team of international researchers led by University of Hawai'i (UH) at Mānoa postdoctoral fellow Jamie Caldwell used a statistical technique typically employed in human epidemiology to determine the ecological risk factors affecting the prevalence of two coral diseases--growth anomalies, abnormalities like coral tumors, and white syndromes, infectious diseases similar to flesh eating bacteria.

Disease-aggravating mutation found in a mouse model of neonatal mitochondrial disease
The new mitochondrial DNA (mtDNA) variant drastically speeds up the disease progression in a mouse model of GRACILE syndrome.

Human longevity largest study of its kind shows early detection of disease & disease risks
Human Longevity, Inc. (HLI) announced the publication of a ground-breaking study in the journal Proceedings of the National Academy of Sciences (PNAS).

30-year study identifies need of disease-modifying therapies for maple syrup urine disease
A new study analyzes 30 years of patient data and details the clinical course of 184 individuals with genetically diverse forms of Maple Syrup Urine Disease (MSUD), which is among the most volatile and dangerous inherited metabolic disorders.

Long-dormant disease becomes most dominant foliar disease in New York onion crops
Until recently, Stemphylium leaf blight has been considered a minor foliar disease as it has not done much damage in New York since the early 1990s.

Read More: Disease News and Disease Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.