Nav: Home

An integrated perspective on diabetic, alcoholic, and drug-induced neuropathy

June 22, 2017

Despite its pervasiveness, many physicians are unfamiliar with how best to treat of NeuP, partly due to few reviews available that integrate basic science with clinical practice. Now, however, a timely review has been published in the Journal of Pain Research aimed at providing clinicians with insight into the etiology of NeuP and educating preclinical scientists on its diagnosis and choice of treatment.

The review, titled "An integrated perspective on diabetic, alcoholic, and drug-induced neuropathy, etiology, and treatment in the US" provides a succinct overview of three different and prevalent neuropathies (diabetic, alcohol- and drug-induced), fusing the combined clinical and preclinical pharmacological expertise in NeuP of the authors.

The lead author, Dr Richard van Rijn from Purdue University, Indiana, USA, said of the review, "In light of the new Center for Disease Control and Prevention recommendations against the use of opioids for chronic pain, we deemed it important to provide an overview of the current understanding of the etiology and pharmacological treatment options for neuropathic pain from the viewpoint of both a practicing physician and a preclinical pharmacologist."

The review discusses the anatomy of pain and pain transmission, with special attention to key ion channels, receptors, and neurotransmitters. Dr Michael Schatman, the Editor in Chief of the Journal of Pain Medicine commented, "This outstanding review is timely and noteworthy in its broad coverage of a wide variety of neuropathies and their treatments."

An understanding of pain neurophysiology will lead to a better understanding of the rationale for the effectiveness of current treatment options, and may lead to better diagnostic tools to help distinguish types of neuropathy. The review also looks at ongoing research efforts to develop additional treatments for NeuP.
-end-
Editor's notes:

The review "An integrated perspective on diabetic, alcoholic, and drug-induced neuropathy, etiology, and treatment in the US" was published in January 2017 (J Pain Res Volume 2017:10 219 -- 228, DOI https://doi.org/10.2147/JPR.S125987)

The Journal of Pain Research is an international, peer-reviewed, open access, online journal that welcomes laboratory and clinical findings in the fields of pain research and the prevention and management of pain. It has a journal Impact Factor of 2.363. The Editor in Chief is Dr Michael Schatman.

Dove Medical Press

Related Chronic Pain Articles:

Breastfeeding may protect against chronic pain after Caesarean section
Breastfeeding after a Caesarean section (C-section) may help manage pain, with mothers who breastfed their babies for at least two months after the operation three times less likely to experience persistent pain compared to those who breastfed for less than two months, according to new research being presented at this year's Euroanaesthesia Congress in Geneva (June 3-5).
Unexpected mechanism behind chronic nerve pain
It has long been assumed that chronic nerve pain is caused by hypersensitivity in the neurons that transmit pain.
Chronic pain amplifies the brain's reaction to new injuries
Chronic pain in any one body part may distort the intensity with which a key brain region perceives pain everywhere else.
How doubts about getting better influence chronic pain treatment success
A leading psychology professor at The University of Texas at Arlington has focused international attention on how a chronic pain patient's irrational doubts about never getting better can influence both his reactions to pain and even treatment outcomes.
New study finds reading can help with chronic pain
A study conducted by researchers from the University of Liverpool, The Reader and the Royal Liverpool University Hospitals Trust, and funded by the British Academy, has found that shared reading (SR) can be a useful therapy for chronic pain sufferers.
Can staying active help to prevent chronic pain? Physical activity affects pain modulation in older adults
Older adults with higher levels of physical activity have pain modulation patterns that might help lower their risk of developing chronic pain, reports a study in PAIN®, the official publication of the International Association for the Study of Pain (IASP).
Poor and less educated suffer the most from chronic pain
Poorer and less-educated older Americans are more like to suffer from chronic pain than those with greater wealth and more education, but the disparity between the two groups is much greater than previously thought, climbing as high as 370 percent in some categories, according to new research by a University at Buffalo medical sociologist.
New study to investigate role of sleep in chronic pain
Washington State University will lead a study to understand the relationship between sleep and chronic pain, part of a nationwide effort to address the rising abuse of opioid pain relievers and expand the arsenal of non-drug treatment options.
UK study to help chronic pain sufferers back to work
Researchers from the University of Warwick's Medical School are leading a novel study to explore ways of helping people with chronic pain back to work.
Chronic pain linked to partners of people with depression
Partners of people with depression are more likely to suffer from chronic pain, research from the University of Edinburgh has found.

Related Chronic Pain Reading:

Best Science Podcasts 2019

We have hand picked the best science podcasts for 2019. Sit back and enjoy new science podcasts updated daily from your favorite science news services and scientists.
Now Playing: TED Radio Hour

Digital Manipulation
Technology has reshaped our lives in amazing ways. But at what cost? This hour, TED speakers reveal how what we see, read, believe — even how we vote — can be manipulated by the technology we use. Guests include journalist Carole Cadwalladr, consumer advocate Finn Myrstad, writer and marketing professor Scott Galloway, behavioral designer Nir Eyal, and computer graphics researcher Doug Roble.
Now Playing: Science for the People

#529 Do You Really Want to Find Out Who's Your Daddy?
At least some of you by now have probably spit into a tube and mailed it off to find out who your closest relatives are, where you might be from, and what terrible diseases might await you. But what exactly did you find out? And what did you give away? In this live panel at Awesome Con we bring in science writer Tina Saey to talk about all her DNA testing, and bioethicist Debra Mathews, to determine whether Tina should have done it at all. Related links: What FamilyTreeDNA sharing genetic data with police means for you Crime solvers embraced...