Death rate dramatically less for young heart attack survivors who quit smoking

July 08, 2020

Boston, MA -- The rate of heart attacks is continuing to increase among individuals younger than 50 years old. While the protective effects of quitting smoking are well documented among older individuals who have experienced a heart attack, the benefits have not been well studied among younger heart attack survivors. In a study published this week in , investigators from
"These results are definitive: among young people who have had a heart attack, quitting smoking is associated with a substantial benefit," said corresponding author

The Partners Young-MI registry holds data from patients younger than 50 who experienced a heart attack and were seen at Brigham and Women's Hospital and Massachusetts General Hospital between January 2000 and April 2016. The registry includes 2,072 individuals. Among them, 1,088 were smokers at the time of their heart attack. Among individuals for whom data on smoking status at one year was available, 343 patients (38 percent) had quit smoking and 567 (62 percent) continued to smoke. Both groups were comparable in terms of age and race.

Over the next ten years, 75 of the persistent smokers (13.2 percent) died compared to 14 (4.1 percent) of those who had quit within a year of their first heart attack. Of the persistent smokers, 30 died of a heart attack or other cardiovascular event (5.3 percent) compared to six (1.7 percent) of those who had quit smoking.

The authors note that given the study's retrospective design, unmeasured factors such as other healthy lifestyle choices may be at play. In addition, the study design did not evaluate long-term smoking status, and thus did not account for those who stopped smoking after one year but then relapsed.

"These limitations notwithstanding, our findings reinforce the critical importance of smoking cessation, especially among those who experience a heart attack at a young age," said Blankstein. "Looking at the trajectories of young patients who quit smoking versus those who don't paints a clear picture of the magnitude of risk compared to the benefit of smoking cessation."
Co-authors of this paper are supported by a T32 postdoctoral training grant from the NHLBI

(T32 HL094301, T32 HL007604). Blankstein reported receiving research support from Amgen Inc and Astellas Inc. A full list of conflict of interest disclosures can be found in the paper.

Paper cited: Blery, DW et al. "Association of Smoking Cessation and Survival Among Young Adults With Myocardial Infarction in the Partners YOUNG-MI Registry" JAMA Network Open DOI:10.1001/jamanetworkopen.2020.9649

Brigham and Women's Hospital

Related Science Articles from Brightsurf:

75 science societies urge the education department to base Title IX sexual harassment regulations on evidence and science
The American Educational Research Association (AERA) and the American Association for the Advancement of Science (AAAS) today led 75 scientific societies in submitting comments on the US Department of Education's proposed changes to Title IX regulations.

Science/Science Careers' survey ranks top biotech, biopharma, and pharma employers
The Science and Science Careers' 2018 annual Top Employers Survey polled employees in the biotechnology, biopharmaceutical, pharmaceutical, and related industries to determine the 20 best employers in these industries as well as their driving characteristics.

Science in the palm of your hand: How citizen science transforms passive learners
Citizen science projects can engage even children who previously were not interested in science.

Applied science may yield more translational research publications than basic science
While translational research can happen at any stage of the research process, a recent investigation of behavioral and social science research awards granted by the NIH between 2008 and 2014 revealed that applied science yielded a higher volume of translational research publications than basic science, according to a study published May 9, 2018 in the open-access journal PLOS ONE by Xueying Han from the Science and Technology Policy Institute, USA, and colleagues.

Prominent academics, including Salk's Thomas Albright, call for more science in forensic science
Six scientists who recently served on the National Commission on Forensic Science are calling on the scientific community at large to advocate for increased research and financial support of forensic science as well as the introduction of empirical testing requirements to ensure the validity of outcomes.

World Science Forum 2017 Jordan issues Science for Peace Declaration
On behalf of the coordinating organizations responsible for delivering the World Science Forum Jordan, the concluding Science for Peace Declaration issued at the Dead Sea represents a global call for action to science and society to build a future that promises greater equality, security and opportunity for all, and in which science plays an increasingly prominent role as an enabler of fair and sustainable development.

PETA science group promotes animal-free science at society of toxicology conference
The PETA International Science Consortium Ltd. is presenting two posters on animal-free methods for testing inhalation toxicity at the 56th annual Society of Toxicology (SOT) meeting March 12 to 16, 2017, in Baltimore, Maryland.

Citizen Science in the Digital Age: Rhetoric, Science and Public Engagement
James Wynn's timely investigation highlights scientific studies grounded in publicly gathered data and probes the rhetoric these studies employ.

Science/Science Careers' survey ranks top biotech, pharma, and biopharma employers
The Science and Science Careers' 2016 annual Top Employers Survey polled employees in the biotechnology, biopharmaceutical, pharmaceutical, and related industries to determine the 20 best employers in these industries as well as their driving characteristics.

Three natural science professors win TJ Park Science Fellowship
Professor Jung-Min Kee (Department of Chemistry, UNIST), Professor Kyudong Choi (Department of Mathematical Sciences, UNIST), and Professor Kwanpyo Kim (Department of Physics, UNIST) are the recipients of the Cheong-Am (TJ Park) Science Fellowship of the year 2016.

Read More: Science News and Science Current Events is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to