Unique new scoring system can predict risk of death from cardiovascular disease

July 12, 2001

A score for predicting risk of death from cardiovascular disease in adults with raised blood pressure, based on individual patient data from randomised controlled trials BMJ Volume 323, pp 75-81

A unique new scoring system for assessing a patient's risk of death from cardiovascular disease is revealed in this week's BMJ. The score will help physicians determine a patient's need for drugs to reduce blood pressure (antihypertensive drugs) and other strategies for improving cardiovascular health.

The score is based on information from eight large trials of antihypertensive drugs, involving over 47,000 men and women across Europe and North America. It uses 11 risk factors, including age, sex, systolic blood pressure and total cholesterol levels, smoking, and diabetes, to quantify an adult's risk of death from cardiovascular heart disease. Points are added for each factor according to its association with risk and patients can be classified simply as high or low risk compared with others of the same age and sex.

Age is a particularly strong risk factor - a woman aged 60-64 has 23 extra points compared with a woman aged 35-39. Sex is also important, with men having 12 extra points. Smoking attributed more in women and younger age groups. In women, cholesterol levels mattered less than in men, whereas diabetes had more of an effect.

As the score is based on a large group of patients in controlled trials of antihypertensive drugs, it has wide applicability in general practices and hypertension clinics, providing a simple means of quantifying a patient's risk of cardiovascular disease based on what should be routinely available information, conclude the authors.
-end-


BMJ

Related Cardiovascular Disease Articles from Brightsurf:

Changes by income level in cardiovascular disease in US
Researchers examined changes in how common cardiovascular disease was in the highest-income earners compared with the rest of the population in the United States between 1999 and 2016.

Fighting cardiovascular disease with acne drug
Researchers from the European Molecular Biology Laboratory (EMBL) in Heidelberg and Stanford University have found the cause of dilated cardiomyopathy - a leading cause of heart failure - and identified a potential treatment for it: a drug already used to treat acne.

A talk with your GP may prevent cardiovascular disease
Having a general practitioner (GP) who is trained in motivational interviewing may reduce your risk of getting cardiovascular disease.

Dilemma of COVID-19, aging and cardiovascular disease
Whether individuals should continue to take angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in the context of coronavirus disease 2019 (COVID-19) is discussed in this article.

Air pollution linked to dementia and cardiovascular disease
People continuously exposed to air pollution are at increased risk of dementia, especially if they also suffer from cardiovascular diseases, according to a study at Karolinska Institutet in Sweden published in the journal JAMA Neurology.

New insights into the effect of aging on cardiovascular disease
Aging adults are more likely to have - and die from - cardiovascular disease than their younger counterparts.

Premature death from cardiovascular disease
National data were used to examine changes from 2000 to 2015 in premature death (ages 25 to 64) from cardiovascular disease in the United States.

Ultrasound: The potential power for cardiovascular disease therapy
In the current issue of Cardiovascular Innovations and Applications volume 4, issue 2, pp.

Despite the ACA, millions of Americans with cardiovascular disease still can't get care
Cardiovascular disease (CVD) is the leading cause of death for Americans, yet millions with CVD or cardiovascular risk factors (CVRF) still can't access the care they need, even years after the implementation of the Affordable Care Act (ACA).

Excess weight and body fat cause cardiovascular disease
In the first Mendelian randomization study to look at this, researchers have found evidence that excess weight and body fat cause a range of heart and blood vessel diseases (rather than just being associated with it).

Read More: Cardiovascular Disease News and Cardiovascular Disease Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.