Special News Report On Prions In 12 July 1996 Science

July 12, 1996

Special News Report on Prions in 12 July 1996 Science
Contact: Diane Dondershine, ddonders@aaas.org
American Association for the Advancement of Science

Special News Report on Prions in 12 July 1996 Science

The recent "mad cow disease" scare has pushed a little known but highly controversial protein into the limelight: the prion (pronounced pree-on), a malfolded and infectious version of a normal cellular protein.

Prions are the suspected culprits behind a number of rare and fatal diseases, including mad cow disease (or bovine spongiform encephalopathy), scrapies, Creutzfeldt-Jakob disease, and kuru. But so far no one has definitively linked prions to these diseases or even proven they exist. A special news report by Rosie Mestel in this issue of Science draws on interviews with 24 researchers on all sides of the issue and takes a detailed look at the evidence for and against prions. Do they represent an entirely new disease process or are they, as some scientists are saying, the "cold fusion" of infectious disease research?

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American Association for the Advancement of Science

Related Prions Articles from Brightsurf:

How understanding the dynamics of yeast prions can shed light on neurodegenerative diseases
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Household bleach inactivates chronic wasting disease prions
A 5-minute soak in a 40% solution of household bleach decontaminated stainless steel wires coated with chronic wasting disease (CWD) prions, according to a new study published in PLOS One.

Mad cow disease: A computational model reveals the mechanism of replication of prions
An article published in the journal PLOS Pathogens reports a realistic computational model for the structure and mechanism of replication of prions, infectious agents responsible for mad cow disease and other neurodegenerative disorders of human and animals.

Breakthrough in chronic wasting disease research reveals distinct deer, elk prion strains
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How prions invade the brain
The spread of prions to the brain does not occur by direct transmission across the blood-brain barrier, according to a study published Nov.

Eyes of CJD patients show evidence of prions
NIH scientists and colleagues have found evidence of the infectious agent of sporadic Creutzfeldt-Jakob disease (CJD) in the eyes of deceased CJD patients.

Creutzfeldt-Jakob disease spreads prions throughout the eyes, researchers find
Researchers recently studied the eyes of 11 people with sporadic Creutzfeldt-Jakob disease (sCJD), the most common and well-known prion disorder.

CWD prions discovered in Wisconsin soils for the first time
New research out of the University of Wisconsin-Madison has, for the first time, detected prions responsible for chronic wasting disease (CWD) in samples taken from sites where deer congregate.

Researchers find infectious prions in Creutzfeldt-Jakob disease patient skin
In a Science Translational Medicine study published today, Case Western Reserve University School of Medicine researchers found that CJD patients also harbor infectious prions in their skin, albeit at lower levels.

Getting under the skin of prion disorders
Infectious prion proteins -- the causative agents of the fatal neurodegenerative disorder Creutzfeldt-Jakob disease -- can be detected in the skin of afflicted individuals, researchers now report.

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