Nav: Home

Overnight brain stimulation improves memory

July 23, 2018

New research in humans demonstrates the potential to improve memory with a non-invasive brain stimulation technique delivered during sleep. The results, published in JNeurosci, come from a project funded by the United States Department of Defense that aims to better understand the process of memory consolidation, which could translate into improved memory function in both healthy and patient populations.

The transfer of memories from the hippocampus to the neocortex for long-term storage is thought to be enabled by synchronization of these parts of the brain during sleep. Nicholas Ketz, Praveen Pilly, and colleagues at University of New Mexico sought to enhance this natural process of overnight reactivation or neural replay to improve memory with a closed-loop transcranial alternating current stimulation system matching the phase and frequency of ongoing slow-wave oscillations during sleep.

Participants were trained and tested on a realistic visual discrimination task in which they had to detect potentially threatening hidden objects and people such as explosive devices and enemy snipers. The researchers found that when participants received stimulation during overnight visits to their sleep laboratory, they showed improved performance in detecting targets in similar but novel situations the next day compared to when they did not receive the stimulation, suggesting an integration of recent experience into a more robust and general memory. Overnight memory changes correlated with stimulation-induced neural changes, which could be used to optimize stimulation in future applications. These findings provide a method for enhancing memory consolidation without disturbing sleep.
-end-
Article: Closed-loop slow-wave tACS improves sleep dependent long-term memory generalization by modulating endogenous oscillations

DOI: https://doi.org/10.1523/JNEUROSCI.0273-18.2018

Corresponding authors: Nicholas Ketz, naketz@hrl.com and Praveen Pilly, pkpilly@hrl.com (HRL Laboratories, Malibu, CA, USA)

About JNeurosci

JNeurosci, the Society for Neuroscience's first journal, was launched in 1981 as a means to communicate the findings of the highest quality neuroscience research to the growing field. Today, the journal remains committed to publishing cutting-edge neuroscience that will have an immediate and lasting scientific impact, while responding to authors' changing publishing needs, representing breadth of the field and diversity in authorship.

About The Society for Neuroscience

The Society for Neuroscience is the world's largest organization of scientists and physicians devoted to understanding the brain and nervous system. The nonprofit organization, founded in 1969, now has nearly 37,000 members in more than 90 countries and over 130 chapters worldwide.

Society for Neuroscience

Related Sleep Articles:

Baby sleeping in same room associated with less sleep, unsafe sleep habits
The American Academy of Pediatrics (AAP) recommends parents keep babies in the same room with them to sleep for the first year to prevent sudden infant death syndrome (SIDS).
Alternating skimpy sleep with sleep marathons hurts attention, creativity in young adults
Skimping on sleep, followed by 'catch-up' days with long snoozes, is tied to worse cognition -- both in attention and creativity -- in young adults, in particular those tackling major projects, Baylor University researchers have found.
Sleep trackers can prompt sleep problems
A researcher and clinician in the sleep disorders program in the Department of Behavioral Sciences at Rush University Medical Center and an associate professor at Rush University, Baron says use of these devices follows a pattern reflected in the title of the Sleep Medicine study: 'Orthosomnia: Are Some Patients Taking the Quantified Self Too Far?'
UW sleep research high-resolution images show how the brain resets during sleep
Striking electron microscope pictures from inside the brains of mice suggest what happens in our own brain every day: Our synapses -- the junctions between nerve cells -- grow strong and large during the stimulation of daytime, then shrink by nearly 20 percent while we sleep, creating room for more growth and learning the next day.
What is good quality sleep? National Sleep Foundation provides guidance
The National Sleep Foundation (NSF) recently released the key indicators of good sleep quality, as established by a panel of experts.
Homeless sleep less, more likely to have insomnia; sleep improvements needed
The homeless sleep less and are more likely to have insomnia and daytime fatigue than people in the general population, findings researchers believe suggest more attention needs to be paid to improving sleep for this vulnerable population, according to a research letter published online by JAMA Internal Medicine.
Losing sleep over discrimination? 'Everyday discrimination' may contribute to sleep problems
People who perceive more discrimination in daily life have higher rates of sleep problems, based on both subjective and objective measures, reports a study in Psychosomatic Medicine: Journal of Biobehavioral Medicine, the official journal of the American Psychosomatic Society.
Mouse mutants with sleep defects may shed light on the mysteries of sleep
The first unbiased genetic screen for sleep defects in mice has yielded two interesting mutants, Sleepy, which sleeps excessively, and Dreamless, which lacks rapid eye movement (REM) sleep.
Brain circuit that drives sleep-wake states, sleep-preparation behavior is identified
Stanford University School of Medicine scientists have identified a brain circuit that's indispensable to the sleep-wake cycle.
Recharge with sleep: Pediatric sleep recommendations promoting optimal health
For the first time, the American Academy of Sleep Medicine has released official consensus recommendations for the amount of sleep needed to promote optimal health in children and teenagers to avoid the health risks of insufficient sleep.

Related Sleep Reading:

Best Science Podcasts 2019

We have hand picked the best science podcasts for 2019. Sit back and enjoy new science podcasts updated daily from your favorite science news services and scientists.
Now Playing: TED Radio Hour

Jumpstarting Creativity
Our greatest breakthroughs and triumphs have one thing in common: creativity. But how do you ignite it? And how do you rekindle it? This hour, TED speakers explore ideas on jumpstarting creativity. Guests include economist Tim Harford, producer Helen Marriage, artificial intelligence researcher Steve Engels, and behavioral scientist Marily Oppezzo.
Now Playing: Science for the People

#524 The Human Network
What does a network of humans look like and how does it work? How does information spread? How do decisions and opinions spread? What gets distorted as it moves through the network and why? This week we dig into the ins and outs of human networks with Matthew Jackson, Professor of Economics at Stanford University and author of the book "The Human Network: How Your Social Position Determines Your Power, Beliefs, and Behaviours".