NIAID announces revised priorities for HIV vaccine research

July 24, 2008

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), is reshaping its research enterprise to broaden HIV vaccine discovery activities. Many of the initiatives have evolved from ideas and opinions recently expressed by scientists either at NIAID's HIV Vaccine Summit on March 25 or in response to two Requests for Information that NIAID issued in April.

There is broad scientific consensus that more extensive vaccine discovery efforts involving laboratory, non-human primate (NHP) and clinical researchers could yield greater understanding of how a successful HIV vaccine might be designed. To that end, NIAID has received approval from its AIDS Research Advisory Committee to develop two major new initiatives to support individual investigator-initiated grants in HIV vaccine discovery and other tactics to interrupt HIV transmission. Information on these initiatives is at http://www.niaid.nih.gov/ncn/budget/concepts/c-aid0508.htm#05 and http://www.niaid.nih.gov/ncn/budget/concepts/c-aid0108.htm#01.

NIAID has also initiated activities to expand NHP research in support of HIV vaccine discovery. First, NIAID is partnering with organizations at NIH and beyond to better track NHP research needs so supply can keep pace with demand. Second, the Institute is planning a workshop on November 12-13, 2008, to explore in detail NHP research needs and approaches and to help guide the design of a future initiative. Third, NIAID's HIV Vaccine Trials Network (HVTN) will promote the exchange of HIV vaccine scientists, particularly new or young HIV vaccine researchers, between NHP laboratories and human clinics to strengthen the bridges between NHP and human research and to ensure more directly comparable results. In addition, NIAID is committed to attracting and retaining young investigators in the field of HIV vaccines by helping them obtain their first grants.

To accommodate this shift of effort and resources toward HIV vaccine discovery research, NIAID plans to reconsider the number of awards in its preclinical HIV vaccine development programs. The Institute also plans to work with the HVTN to ensure that its clinical research infrastructure is nimble, expandable and contractible as the number and size of clinical studies dictate.
-end-
ARTICLE: AS Fauci et al. HIV Vaccine Research: The Way Forward. Science 321(5888) (2008).

WHO: Anthony S. Fauci, M.D., the director of NIAID, and Margaret Johnston, Ph.D., the director of the Vaccine Research Program in NIAID's Division of AIDS, are available to comment on this article.

CONTACT: To schedule interviews, contact the NIAID Office of Communications, 301-402-1663, niaidnews@niaid.nih.gov.

NIAID is a component of the National Institutes of Health. NIAID supports basic and applied research to prevent, diagnose and treat infectious diseases such as HIV/AIDS and other sexually transmitted infections, influenza, tuberculosis, malaria and illness from potential agents of bioterrorism. NIAID also supports research on basic immunology, transplantation and immune-related disorders, including autoimmune diseases, asthma and allergies.

The National Institutes of Health (NIH)--The Nation's Medical Research Agency--includes 27 Institutes and Centers and is a component of the U. S. Department of Health and Human Services. It is the primary federal agency for conducting and supporting basic, clinical and translational medical research, and it investigates the causes, treatments and cures for both common and rare diseases. For more information about NIH and its programs, visit http://www.nih.gov.

News releases, fact sheets and other NIAID-related materials are available on the NIAID Web site at <http://www.niaid.nih.gov>

NIH/National Institute of Allergy and Infectious Diseases

Related Infectious Diseases Articles from Brightsurf:

Understanding the spread of infectious diseases
Physicists at M√ľnster University (Germany) have shown in model simulations that the COVID-19 infection rates decrease significantly through social distancing.

Forecasting elections with a model of infectious diseases
Election forecasting is an innately challenging endeavor, with results that can be difficult to interpret and may leave many questions unanswered after close races unfold.

COVID-19 a reminder of the challenge of emerging infectious diseases
The emergence and rapid increase in cases of coronavirus disease 2019 (COVID-19), a respiratory illness caused by a novel coronavirus, pose complex challenges to the global public health, research and medical communities, write federal scientists from NIH's National Institute of Allergy and Infectious Diseases (NIAID) and from the Centers for Disease Control and Prevention (CDC).

Certain antidepressants could provide treatment for multiple infectious diseases
Some antidepressants could potentially be used to treat a wide range of diseases caused by bacteria living within cells, according to work by researchers in the Virginia Commonwealth University School of Medicine and collaborators at other institutions.

Opioid epidemic is increasing rates of some infectious diseases
The US faces a public health crisis as the opioid epidemic fuels growing rates of certain infectious diseases, including HIV/AIDS, hepatitis, heart infections, and skin and soft tissue infections.

Infectious diseases could be diagnosed with smartphones in sub-Saharan Africa
A new Imperial-led review has outlined how health workers could use existing phones to predict and curb the spread of infectious diseases.

The Lancet Infectious Diseases: Experts warn of a surge in vector-borne diseases as humanitarian crisis in Venezuela worsens
The ongoing humanitarian crisis in Venezuela is accelerating the re-emergence of vector-borne diseases such as malaria, Chagas disease, dengue, and Zika virus, and threatens to jeopardize public health gains in the country over the past two decades, warn leading public health experts.

Glow-in-the-dark paper as a rapid test for infectious diseases
Researchers from Eindhoven University of Technology (The Netherlands) and Keio University (Japan) present a practicable and reliable way to test for infectious diseases.

Math shows how human behavior spreads infectious diseases
Mathematics can help public health workers better understand and influence human behaviors that lead to the spread of infectious disease, according to a study from the University of Waterloo.

Many Americans say infectious and emerging diseases in other countries will threaten the US
An overwhelming majority of Americans (95%) think infectious and emerging diseases facing other countries will pose a 'major' or 'minor' threat to the U.S. in the next few years, but more than half (61%) say they are confident the federal government can prevent a major infectious disease outbreak in the US, according to a new national public opinion survey commissioned by Research!America and the American Society for Microbiology.

Read More: Infectious Diseases News and Infectious Diseases Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.