Stature and education level of diabetic women to find those at risk of dementia in Nigeria

July 26, 2019

* A joint survey by researchers from the Universitat Autònoma de Barcelona (UAB) and Benue State University (BSU) finds that short height and low education levels are characteristic traits of Nigerian women with type 2 diabetes showing early symptoms of dementia.

* This work points to the importance of childhood nutrition and education programmes, particularly for girls, in public health improvement strategies in Nigeria. A sustained programme addressing these problems can mitigate a future burden of dementia in the country's adult diabetic women.

Globally, DM2 in mid-life is a recognized risk factor for dementia, but this association is worse in persons of African descent, especially in women. Among African diabetics, development of dementia is more frequent and rapid, and this is associated with different factors such as lifestyle, diet, socio-economy and genetics.

This appears to be the case in Nigeria, which currently contains the largest number of persons (3 million and rising) affected by DM2 on the African continent. This makes the country a good place to study the interaction of varied factors in the development of DM and associated co-morbidities in persons of African origin. In the 1960s, the prevalence of DM in Nigeria was found to be less than 1% but this has risen to 4.6%-10%, depending on the study population within the country, in about 5 decades. Some factors implicated in this surge are ageing, obesity, hypertension, adoption of sedentary living and wide consumption of toxic diet imported from some Western countries.

Taking into account the above information, Dr. Lydia Giménez Llort (Head of the Medical Psychology Departamental Unit, representative of the Observatory for the Equality at the Faculty of Medicine, and researcher at the Institute of Neurosciences, UAB) and Dr. Efosa Kenneth Oghagbon (Department of Chemical Pathology, Faculty of Basic & Allied Medical Science, College of Health Sciences, Benue State University (BSU) and Consultant Chemical Pathologist and Metabolic Physician at the University Teaching Hospital; BSUTH, Makurdi, Nigeria) carried out a collaborative study that evaluated factors associating DM2 with dementia in a sub-Saharan population of type 2 diabetic subjects. This comprised 62 female and 47 male patients, who were compared with 53 healthy female and 46 healthy male subjects, with special attention put on the women.

Using two dementia questionnaires/scales, the mini-mental state examination (MMMS) and six item cognitive impair test (6CIT), researchers assessed the impact of anthropometric measures (body mass index, waist-hip ratio, weight and height) and other biodata (sex, age, education level and professions) on the burden of dementia.

The study results showed that diabetic women who had shorter body height and lower level of education had more severe dementia. The women afflicted with dementia had twice the level of illiteracy compared to their healthy counterparts, and this was worse compared to men who were 11 times better in literacy level. The stature or height was the most discriminating factor among the physical measures and the diabetic women in the study were generally shorter. Categorically, the two dementia scales showed that diabetic Nigerian women with shorter stature and poorer education levels had grades consistent with cognitive deterioration.

Physical height is a simple parameter that can be measured by most medical clinics in Nigeria. It should be integrated into routine assessment of diabetic patients, especially women as it can reveal increased dementia risk. The final height of adults is related to early life nutrition and thus there is the need for better feeding in childhood especially among girls and pregnant women.

Dr. Lydia Giménez-Llort emphasised that " augments the cognitive reserve of individuals, and this favors brain neuroplasticity and functional development". Furthermore the UAB scientist said that " addition to age, complications of diabetes constitutes a key predictive tool for dementia".

Dr. Efosa K. Oghagbon suggests that "an optimal nutrition at the onset of life can improve cognition and cerebral development in childhood and adolescence; key period during which to attain adequate physical and educational developments of the Nigerian child".

Both authors agree that not only is it important for government and policy makers to emphasise proper childhood nutrition in Nigerians, but should particularly focus on the girl child.

"Our results can aid the development of evidence-based public health approaches to mitigate dementia in communities in Nigeria and the sub-region. This is important as countries in the sub-region including Nigeria cannot sustain healthcare cost occasioned by dementia and associated issues", opine the two researchers.
This study received financial support from the BSU and the UAB's Fundació Autònoma Solidària (FAS), a social entity of UAB that promotes projects containing elements of university cooperation for educational development (UAB, Spain and BSU, Nigeria). It is made up of university funding and contributions from faculty members (PDI), administrative staff members (PAS), and students through their donations when enrolling. The management of BSU and the University Teaching Hospital (BSUTH), were immensely supportive of this project.

Universitat Autonoma de Barcelona

Related Science Articles from Brightsurf:

75 science societies urge the education department to base Title IX sexual harassment regulations on evidence and science
The American Educational Research Association (AERA) and the American Association for the Advancement of Science (AAAS) today led 75 scientific societies in submitting comments on the US Department of Education's proposed changes to Title IX regulations.

Science/Science Careers' survey ranks top biotech, biopharma, and pharma employers
The Science and Science Careers' 2018 annual Top Employers Survey polled employees in the biotechnology, biopharmaceutical, pharmaceutical, and related industries to determine the 20 best employers in these industries as well as their driving characteristics.

Science in the palm of your hand: How citizen science transforms passive learners
Citizen science projects can engage even children who previously were not interested in science.

Applied science may yield more translational research publications than basic science
While translational research can happen at any stage of the research process, a recent investigation of behavioral and social science research awards granted by the NIH between 2008 and 2014 revealed that applied science yielded a higher volume of translational research publications than basic science, according to a study published May 9, 2018 in the open-access journal PLOS ONE by Xueying Han from the Science and Technology Policy Institute, USA, and colleagues.

Prominent academics, including Salk's Thomas Albright, call for more science in forensic science
Six scientists who recently served on the National Commission on Forensic Science are calling on the scientific community at large to advocate for increased research and financial support of forensic science as well as the introduction of empirical testing requirements to ensure the validity of outcomes.

World Science Forum 2017 Jordan issues Science for Peace Declaration
On behalf of the coordinating organizations responsible for delivering the World Science Forum Jordan, the concluding Science for Peace Declaration issued at the Dead Sea represents a global call for action to science and society to build a future that promises greater equality, security and opportunity for all, and in which science plays an increasingly prominent role as an enabler of fair and sustainable development.

PETA science group promotes animal-free science at society of toxicology conference
The PETA International Science Consortium Ltd. is presenting two posters on animal-free methods for testing inhalation toxicity at the 56th annual Society of Toxicology (SOT) meeting March 12 to 16, 2017, in Baltimore, Maryland.

Citizen Science in the Digital Age: Rhetoric, Science and Public Engagement
James Wynn's timely investigation highlights scientific studies grounded in publicly gathered data and probes the rhetoric these studies employ.

Science/Science Careers' survey ranks top biotech, pharma, and biopharma employers
The Science and Science Careers' 2016 annual Top Employers Survey polled employees in the biotechnology, biopharmaceutical, pharmaceutical, and related industries to determine the 20 best employers in these industries as well as their driving characteristics.

Three natural science professors win TJ Park Science Fellowship
Professor Jung-Min Kee (Department of Chemistry, UNIST), Professor Kyudong Choi (Department of Mathematical Sciences, UNIST), and Professor Kwanpyo Kim (Department of Physics, UNIST) are the recipients of the Cheong-Am (TJ Park) Science Fellowship of the year 2016.

Read More: Science News and Science Current Events is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to