Incidence of nonmelanoma skin cancer on the rise among young adults

August 09, 2005

A new study from Minnesota finds the incidence of nonmelanoma skin cancer increasing among men and women under the age of 40, according to an article in the August 10 issue of JAMA.

The overall incidence of nonmelanoma skin cancer, consisting of squamous cell carcinoma (SCC) and basal cell carcinoma (BCC), is increasing, according to background information in the article. This increasing incidence is most likely due to a combination of factors, including increased exposure to UV light, ozone depletion, and increased surveillance. Long-term exposure to the sun resulting in photodamage is perhaps the biggest risk factor for nonmelanoma skin cancer. In the United States, approximately 800,000 new cases of BCC and 200,000 new cases of SCC were diagnosed in 2000. Nonmelanoma skin cancer generally occurs in persons older than 50 years, and in this age group, its incidence is increasing rapidly. However, little is known about its incidence in persons younger than 40 years.

Leslie J. Christenson, M.D., of Mayo Clinic, Rochester, Minn., and colleagues conducted a study to estimate the sex- and age-specific incidence of BCC and SCC in Olmsted County, Minnesota, in a young population (less than 40 years old) from the beginning of 1976 through 2003. The patients in this study have comprehensive medical records captured through the Rochester Epidemiology Project.

During the study period, 451 incident basal cell carcinomas were diagnosed in 417 patients, and 70 incident squamous cell carcinomas were diagnosed in 68 patients. Overall, the age-adjusted incidence of basal cell carcinoma per 100,000 persons was 25.9 for women and 20.9 for men. The incidence of basal cell carcinoma increased significantly during the study period among women but not among men. Nodular basal cell carcinoma was the most common histologic subtype; 43.0 percent of tumors were solely nodular basal cell carcinoma and 11.0 percent had a mixed composition, including the nodular subtype. The incidence of squamous cell carcinoma was similar in men and women, with an average age- and sex-adjusted incidence of 3.9 per 100,000 persons; the incidence of squamous cell carcinoma increased significantly over the study period among both women and men.

Comparing the change in incidence rates for basal cell carcinoma, per 100,000 persons the rate for 1976-1979 for women was 13.4; for men, 22.9, and for both sexes, 18.2. For 2000-2003, the rate for women was 31.6; for men, 26.7; and for both sexes, 29.1.

For squamous cell carcinoma, per 100,000 persons the rate for 1976-1979 for women was 0.6; for men, 1.3, and for both sexes, 0.9. For 2000-2003, the rate for women was 4.1; for men, 4.2; and for both sexes, 4.1.

"This increase [in nonmelanoma skin cancer in young adults] may lead to an exponential increase in the overall occurrence of nonmelanoma skin cancer over time as the population ages. This may mean even greater demands for health care related to nonmelanoma skin cancer. Our results also emphasize the need to focus on the prevention of skin cancer in the very young so that the increasing incidence of a potentially preventable cancer can be halted," the authors conclude.
-end-
(JAMA. 2005; 294:681-690. Available pre-embargo to the media at www.jamamedia.org.)

The JAMA Network Journals

Related Skin Cancer Articles from Brightsurf:

Increasing the effectiveness of immunotherapy against skin cancer
Researchers at the University of Bern have discovered a mechanism in the body's own immune system which is responsible for the maturation and activation of immune cells.

New electronic skin can react to pain like human skin
New pain-sensing prototype mimics the body's near-instant feedback response and reacts to painful sensations with the same lighting speed that nerve signals travel to the brain.

Studying how skin cancer starts
New research by Ortiz-Rodríguez and mentor Carlos Crespo, a professor and lead researcher in the The Crespo Group lab, reveals for perhaps the first time how quickly certain pre-cancerous lesions can form on the DNA of our skin when exposed to sunlight.

Skin-to-skin 'kangaroo care' shows important benefits for premature babies
A world-first study led by Monash University has demonstrated significant benefits to a premature baby's heart and brain function when held by the parent in skin-to-skin contact.

Mother/infant skin-to-skin touch boosts baby's brain development and function
As the world prioritizes social distancing due to COVID-19, research shows that extended use of Kangaroo Care, a skin-to-skin, chest-to-chest method of caring for a baby, can positively benefit full-term infants and their mothers, with important implications for post-partum depression.

IU researcher makes skin cancer discovery
An Indiana University cancer researcher has identified eight new genomic regions that increase a person's risk for skin cancer.

Skin-to-skin contact do not improve interaction between mother and preterm infant
Following a premature birth it is important that the parents and the infant quickly establish a good relationship.

Research reveals potential dangers during skin-to-skin contact for mother and baby following cesarean section birth
Research in the latest edition of the European Journal of Anaesthesiology (the official journal of the European Society of Anaesthesiology) reports the potential dangers of allowing skin-to-skin contact for mother and baby in the operating room, following a cesarean section birth.

Helping skin cells differentiate could be key to treating common skin cancer
A new study from Penn researchers has identified the key regulator that controls how the skin replaces itself and which can determine if cells turn into cancer.

Protein linked to aggressive skin cancer
Almost 300,000 people worldwide develop malignant melanoma each year. The disease is the most serious form of skin cancer and the number of cases reported annually is increasing, making skin cancer one of Sweden's most common forms of cancer.

Read More: Skin Cancer News and Skin Cancer Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.