Cycles of Cutaneous leishmaniasis are linked to climate

August 14, 2006

Cutaneous leishmaniasis occurs in cycles that are related to temperature and the El Niño Southern Oscillation. Luis Chaves and Mercedes Pascual from the University of Michigan studied monthly data, between 1991 and 2001, of the incidence of cutaneous leishmaniasis in Costa Rica.

Using mathematical models they were able to show that this disease has cycles of approximately 3 y that are related to temperature and indices of the El Niño Southern Oscillation, including the sea surface temperature. Using such a model they could predict the incidence of cutaneous leishmaniasis up to 12 months ahead, with an accuracy of between 72% and 77%.

Cutaneous leishmaniasis is one of the main emerging diseases in the Americas. As in other vector-transmitted diseases, its transmission is sensitive to the environment, but this is the first study to look at the interannual patterns of cycling of the disease.
-end-
Citation: Chaves LF, Pascual M (2006) Climate cycles and forecasts of cutaneous leishmaniasis, a nonstationary vector-borne disease. PLoS Med 3(8): e295.

PLEASE ADD THE LINK TO THE PUBLISHED ARTICLE IN ONLINE VERSIONS OF YOUR REPORT: http://dx.doi.org/10.1371/journal.pmed.0030295

PRESS-ONLY PREVIEW OF THE ARTICLE: http://www.plos.org/press/plme-03-08-chaves.pdf

Related image for press use: http://www.plos.org/press/plme-03-08-chaves.jpg

· Caption: Cross-wavelet analysis for temperature and cases

CONTACT:
Luis Chaves
University of Michigan
Ecology and Evolutionary Biology
830 North University
Natural Science (Kraus) Building
Ann Arbor, MI 48109 United States of America
+1-734-615-9805
+1-734-763-0544 (fax)
lfchaves@umich.edu

THE FOLLOWING RESEARCH ARTICLE WILL ALSO BE PUBLISHED ONLINE:

Mycobacterium tuberculosis Induces Interleukin-32 Production through a Caspase- 1/IL-18/Interferon-γ-Dependent Mechanism

Synthesis of IL-32, a cell-associated proinflammatory cytokine, was promoted by Mycobacterium tuberculosis and M. bovis, suggesting a role in a role in inflammation and host defense against tuberculosis.

Citation: Netea MG, Azam T, Lewis EC, Joosten LAB, Wang M, et al. (2006) Mycobacterium tuberculosis induces interleukin-32 production through a caspase-1/IL-18/interferon-γ-dependent mechanism. PLoS Med 3(8): e277.

PLEASE ADD THE LINK TO THE PUBLISHED ARTICLE IN ONLINE VERSIONS OF YOUR REPORT: http://dx.doi.org/10.1371/journal.pmed.0030277

PRESS-ONLY PREVIEW OF THE ARTICLE: http://www.plos.org/press/plme-03-08-netea.pdf

CONTACT:
Mihai Netea
Radboud University Nijmegen Medical Center
Department of Medicine
Geert Grooteplein 8
Nijmegen, 6500 HB Netherlands
+31-24-3618819
M.Netea@aig.umcn.

All works published in PLoS Medicine are open access. Everything is immediately available without cost to anyone, anywhere--to read, download, redistribute, include in databases, and otherwise use--subject only to the condition that the original authorship is properly attributed. Copyright is retained by the authors. The Public Library of Science uses the Creative Commons Attribution License.

About PLoS Medicine
PLoS Medicine is an open access, freely available international medical journal. It publishes original research that enhances our understanding of human health and disease, together with commentary and analysis of important global health issues. For more information, visit http://www.plosmedicine.org

About the Public Library of Science
The Public Library of Science (PLoS) is a non-profit organization of scientists and physicians committed to making the world's scientific and medical literature a freely available public resource. For more information, visit http://www.plos.org

PLOS

Related Disease Articles from Brightsurf:

CLCN6 identified as disease gene for a severe form of lysosomal neurodegenerative disease
A mutation in the CLCN6 gene is associated with a novel, particularly severe neurodegenerative disorder.

Cellular pathway of genetic heart disease similar to neurodegenerative disease
Research on a genetic heart disease has uncovered a new and unexpected mechanism for heart failure.

Mechanism linking gum disease to heart disease, other inflammatory conditions discovered
The link between periodontal (gum) disease and other inflammatory conditions such as heart disease and diabetes has long been established, but the mechanism behind that association has, until now, remained a mystery.

Potential link for Alzheimer's disease and common brain disease that mimics its symptoms
A new study by investigators from Brigham and Women's Hospital uncovered a group of closely related genes that may capture molecular links between Alzheimer's disease and Limbic-predominant Age-related TDP-43 Encephalopathy, or LATE, a recently recognized common brain disorder that can mimic Alzheimer's symptoms.

Antioxidant agent may prevent chronic kidney disease and Parkinson's disease
Researchers from Osaka University developed a novel dietary silicon-based antioxidant agent with renoprotective and neuroprotective effects.

Tools used to study human disease reveal coral disease risk factors
In a study published in Scientific Reports, a team of international researchers led by University of Hawai'i (UH) at Mānoa postdoctoral fellow Jamie Caldwell used a statistical technique typically employed in human epidemiology to determine the ecological risk factors affecting the prevalence of two coral diseases--growth anomalies, abnormalities like coral tumors, and white syndromes, infectious diseases similar to flesh eating bacteria.

Disease-aggravating mutation found in a mouse model of neonatal mitochondrial disease
The new mitochondrial DNA (mtDNA) variant drastically speeds up the disease progression in a mouse model of GRACILE syndrome.

Human longevity largest study of its kind shows early detection of disease & disease risks
Human Longevity, Inc. (HLI) announced the publication of a ground-breaking study in the journal Proceedings of the National Academy of Sciences (PNAS).

30-year study identifies need of disease-modifying therapies for maple syrup urine disease
A new study analyzes 30 years of patient data and details the clinical course of 184 individuals with genetically diverse forms of Maple Syrup Urine Disease (MSUD), which is among the most volatile and dangerous inherited metabolic disorders.

Long-dormant disease becomes most dominant foliar disease in New York onion crops
Until recently, Stemphylium leaf blight has been considered a minor foliar disease as it has not done much damage in New York since the early 1990s.

Read More: Disease News and Disease Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.