Nav: Home

New book on Antibiotics and Antibiotic Resistance from CSHLPress

August 17, 2016

One of the greatest medical accomplishments of the past century was the introduction of antibiotics into the clinic. However, the use of these lifesaving drugs rapidly led to the emergence of antibiotic-resistant pathogens, which have become increasingly difficult and expensive to eradicate. Antibiotic resistance now severely limits our ability to curb infectious diseases and is therefore a major global health concern.

Written and edited by experts in the field, Antibiotics and Antibiotic Resistance from Cold Spring Harbor Perspectives in Medicine examines the major classes of antibiotics, together with their modes of action and mechanisms of resistance. Well-established antibiotics (e.g., β-lactams) are covered, as are lesser-used drugs that have garnered recent interest (e.g., polymyxins) and new compounds in the development pipeline. The contributors describe the mechanisms by which the agents disrupt cell wall assembly and maintenance, membrane synthesis and integrity, DNA and RNA metabolism, protein synthesis, and the folate cycle. They also examine how bacteria evolve ways to resist these disruptions by modifying the drug or drug target or by controlling access of the drug to the cell.

The authors also explore the environmental origins of antibiotic resistance and provide guidance on the rational development and therapeutic application of new antibiotics. This volume is therefore an essential reference for microbiologists, pharmacologists, infectious disease biologists, and all concerned with this medical crisis.
-end-


Cold Spring Harbor Laboratory

Related Antibiotics Articles:

Antibiotics promote resistance on experimental croplands
Canadian researchers have generated both novel and existing antibiotic resistance mechanisms on experimental farmland, by exposing the soil to specific antibiotics.
Why antibiotics fail
UCSB biologists correct a flaw in the way bacterial susceptibility to these drugs is tested.
Fungi have enormous potential for new antibiotics
Fungi are a potential goldmine for the production of pharmaceuticals.
Antibiotics can boost bacterial reproduction
The growth of bacteria can be stimulated by antibiotics, scientists at the University of Exeter have discovered.
Last-line antibiotics are failing
The ECDC's latest data on antimicrobial resistance and consumption shows that in 2015, antibiotic resistance continued to increase for most bacteria and antibiotics under surveillance.
Two antibiotics fight bacteria differently than thought
Two widely prescribed antibiotics -- chloramphenicol and linezolid -- may fight bacteria in a different way from what scientists and doctors thought for years, University of Illinois at Chicago researchers have found.
Preserving the power of antibiotics
News release describes efforts to address inappropriate antibiotic prescribing in emergency departments and urgent-care centers nationwide, which a JAMA study published this past May found rates as high as 50 percent for acute respiratory infections in US emergency departments.
Antibiotics could be cut by up to one-third, say dairy farmers
Nine in 10 dairy farmers participating in a new survey from the Royal Association of British Dairy Farmers (RADBF) say that the farming industry must take a proactive lead in the battle against antibiotic resistance.
Antibiotics may be inappropriate for uncomplicated diverticulitis
Antibiotics are advised in most guidelines on diverticulitis, which arises when one or more small pouches in the digestive tract become inflamed or infected.
New book on Antibiotics and Antibiotic Resistance from CSHLPress
'Antibiotics and Antibiotic Resistance' from CSHLPress examines the major classes of antibiotics, together with their modes of action and mechanisms of resistance.

Related Antibiotics Reading:

Antibiotics Simplified
by Jason C. Gallagher (Author), Conan MacDougall (Author)

Azithromycin: Magical Pills That Cure Bacterial Infections Like Lime Disease, Chlamydia, Sinus Infections, Anthrax, Reproductive Organ And Malaria.
by Awate Simon (Author)

EMRA Antibiotic Guide, 17th Edition
by MD Brian J. Levine (Author)

Azithromycin: Active Antibiotics Pills that Eliminates Chlamydia, Gonorrhea, STD, UTI, Pneumonia, Bronchitis, Sinusitis, & Bacterial Infections of the Ear, Stomach, Tooth, & Skin
by Christine R. Funke (Author)

Doxycycline: The Ultimate Antibiotics For Treating Bacterial Infections Like Pneumonia, Acne, Chlamydia Infections, Early Lyme Disease, Cholera and Syphilis (STI’s) & Maleria.
by Jane D. Duncan (Author)

Amoxicillin: Informative Guide on the Perfectly Working Antibiotics for Combating Bacteria Infections
by Anneliese W. Weikel (Author)

Antibiotic Basics for Clinicians: The ABCs of Choosing the Right Antibacterial Agent
by Alan R. Hauser MD PhD (Author)

Amoxicillin: The Best Antibiotic Drug To Completely Treat Bacterial Infection
by Janet Kelvin (Author)

EMRA Antibiotic Guide, 18th ed.
by MD Brian J. Levine (Author)

Herbal Antibiotics, 2nd Edition: Natural Alternatives for Treating Drug-resistant Bacteria
by Stephen Harrod Buhner (Author)

Best Science Podcasts 2018

We have hand picked the best science podcasts for 2018. Sit back and enjoy new science podcasts updated daily from your favorite science news services and scientists.
Now Playing: TED Radio Hour

Hacking The Law
We have a vision of justice as blind, impartial, and fair — but in reality, the law often fails those who need it most. This hour, TED speakers explore radical ways to change the legal system. Guests include lawyer and social justice advocate Robin Steinberg, animal rights lawyer Steven Wise, political activist Brett Hennig, and lawyer and social entrepreneur Vivek Maru.
Now Playing: Science for the People

#495 Earth Science in Space
Some worlds are made of sand. Some are made of water. Some are even made of salt. In science fiction and fantasy, planet can be made of whatever you want. But what does that mean for how the planets themselves work? When in doubt, throw an asteroid at it. This is a live show recorded at the 2018 Dragon Con in Atlanta Georgia. Featuring Travor Valle, Mika McKinnon, David Moscato, Scott Harris, and moderated by our own Bethany Brookshire. Note: The sound isn't as good as we'd hoped but we love the guests and the conversation and we wanted to...