Nav: Home

Digital calculator provides the estimated risk for GIST recurrence

August 17, 2016

GIST (Gastrointestinal Stromal Tumor) is an uncommon type of sarcoma found in the tissues supporting the digestive system (stomach and intestines). Approximately one percent of all gastrointestinal cancers are GISTs. The digital calculator predicts the risk for GIST recurrence based on tumor size, mitotic count, tumor site and rupture.

"Providing the patient with a reliable estimation of recurrence is faster with the digital calculator. Expensive drugs that can also have side-effects can thus be targeted to the high-risk patients who are not likely to be cured by surgery alone. The risk estimation should be examined together with the patient in order to guarantee that the patient understands the reasons behind treatment decisions", explains Heikki Joensuu, Professor of Oncology at the University of Helsinki, and the Research Director at the Helsinki Comprehensive Cancer Centre.

Risk estimations based on a uniquely large sample and accurate modelling

The GIST Risk calculator is based on research conducted by Prof. Heikki Joensuu and his co-workers where an international sample of 2000 diagnosed GIST patients were analyzed with the help of a mathematical model designed by Prof. Aki Vehtari of Aalto University.

"The nonlinear mathematic model predicts the combined effect of the main prognostic factors more accurately than any known model before. However, it is important to note that the historical data is solely comprised of patients that were treated via surgery only, and that new targeted therapy drugs have reduced the risk of recurrence. The prognostic contour maps resulting from non-linear modelling have been widely accepted by doctors, but digital calculator significantly improves the usability of the maps", informs Aki Vehtari, Professor at the Aalto University.

"GIST Risk calculator is a great example of how preventive cancer care can be further developed by using modern technology to analyze health data, and proof of the improved results that can be achieved through cooperation of startups, hospitals and universities", states Lauri Sippola, CEO of Netmedi.

The GIST Risk Calculator is accessible online for all cancer care and research professionals.
-end-


Netmedi

Related Cancer Care Articles:

Why fewer blood cancer patients receive hospice care
Research has shown that patients with blood cancers are less likely to enroll in hospice care than patients with solid cancers, and the findings from a national survey suggest that concerns about the adequacy of hospice may prevent blood cancer specialists from referring their patients.
ASCO and Cancer Care Ontario update guideline on radiation therapy for prostate cancer
The American Society of Clinical Oncology (ASCO) and Cancer Care Ontario today issued a joint clinical practice guideline update on brachytherapy (internal radiation) for patients with prostate cancer.
Palliative care consults for advanced cancer patients reduces hospitalization and improves care
Cancer patients admitted to the hospital with advanced stages of disease who were referred early to palliative care had decreased health care utilization and increased use of support services following discharge, according to a new study led by researchers at the Icahn School of Medicine at Mount Sinai.
Research into palliative care top priority for cancer patients
How and when people are referred to palliative care should be prioritised according to cancer patients, a new study in the Oncology Nursing Forum has found.
Study finds not all women get appropriate care for cervical cancer
Fewer than three out of five women with cervical cancer received guideline-based care, a new study finds.
More Cancer Care News and Cancer Care Current Events

Best Science Podcasts 2019

We have hand picked the best science podcasts for 2019. Sit back and enjoy new science podcasts updated daily from your favorite science news services and scientists.
Now Playing: TED Radio Hour

Anthropomorphic
Do animals grieve? Do they have language or consciousness? For a long time, scientists resisted the urge to look for human qualities in animals. This hour, TED speakers explore how that is changing. Guests include biological anthropologist Barbara King, dolphin researcher Denise Herzing, primatologist Frans de Waal, and ecologist Carl Safina.
Now Playing: Science for the People

#534 Bacteria are Coming for Your OJ
What makes breakfast, breakfast? Well, according to every movie and TV show we've ever seen, a big glass of orange juice is basically required. But our morning grapefruit might be in danger. Why? Citrus greening, a bacteria carried by a bug, has infected 90% of the citrus groves in Florida. It's coming for your OJ. We'll talk with University of Maryland plant virologist Anne Simon about ways to stop the citrus killer, and with science writer and journalist Maryn McKenna about why throwing antibiotics at the problem is probably not the solution. Related links: A Review of the Citrus Greening...