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Type 2 diabetes may affect heart structure and increase complications and death among heart failure patients of Asian ethnicity

August 21, 2019

DALLAS, August 21, 2019 -- Type 2 diabetes affects the structure of the heart in heart failure patients and increases their risk for repeat hospitalizations and/or death, according to new research published in the Journal of the American Heart Association, the Open Access Journal of the American Heart Association/American Stroke Association.

Type 2 diabetes frequently coexists with heart failure, and the prevalence of diabetes has increased worldwide. While diabetes and heart failure together have been extensively studied among Western populations, there is less known about their collective impact among Asian populations. An international team of researchers analyzed data from more than nearly 6,200 heart failure patients participating in the ASIAN-HF Study.

The study found that having Type 2 diabetes and heart failure was associated with:
  • structural abnormalities in the heart;

  • poorer quality of life; and

  • increased risk of heart failure-related re-hospitalizations and/or death within one year.
Researchers also noted that the overall prevalence of Type 2 diabetes was high among these heart failure patients, with more than 40% having diabetes. The prevalence was highest in Singapore and Hong Kong.

"Primary prevention strategies and tailored treatment options are needed to tackle this twin scourge of diseases," said study co-author Jonathan Yap, M.B.B.S., M.P.H., consultant from the department of cardiology of the National Heart Centre Singapore. "Our findings emphasize the need for preventative public health measures at the community and primary care level. For heart failure patients who have diabetes, physicians should closely monitor and optimize their management."
-end-
Co-authors are Wan Ting Tay, M.App.Stat.; Tiew-Hwa Katherine Teng, M.P.H., Ph.D.; Inder Anand, M.D., Ph.D.; A. Mark Richards, M.D., Ph.D.; Lieng Hsi Ling, M.B.B.S., M.D.; Michael R. MacDonald, M.B.Ch.B.; Chanchal Chandramouli, Ph.D.; Jasper Tromp, M.D., Ph.D.; Bambang B. Siswanto, M.D., Ph.D.; Michael Zile, M.D., Ph.D.; John McMurray, M.B.Ch.B. (Hons) M.D.; and Carolyn S.P. Lam, M.B.B.S., Ph.D.

Author disclosures are on the manuscript. The ASIAN-HF study is supported by grants from National Medical Research Council (NMRC) Singapore, Agency for Science, Technology and Research (A*STAR) Biomedical Research Council's Asian neTwork for Translational Research and Cardiovascular Trials (ATTRaCT) program, Boston Scientific Investigator Sponsored Research Program and Bayer.

Additional Resources:

Available multimedia is on right column of release link - https://newsroom.heart.org/news/type-2-diabetes-may-affect-heart-structure-and-increase-complications-and-death-among-heart-failure-patients-of-asian-ethnicity?preview=290cfaa82007a01fe4c338c0084aeb73

After August 21, view the manuscript online.

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Statements and conclusions of study authors published in American Heart Association scientific journals are solely those of the study authors and do not necessarily reflect the Association's policy or position. The Association makes no representation or guarantee as to their accuracy or reliability. The Association receives funding primarily from individuals; foundations and corporations (including pharmaceutical, device manufacturers and other companies) also make donations and fund specific Association programs and events. The Association has strict policies to prevent these relationships from influencing the science content. Revenues from pharmaceutical and device corporations and health insurance providers are available at https://www.heart.org/en/about-us/aha-financial-information.

About the American Heart Association

The American Heart Association is a relentless force for a world of longer, healthier lives. We are dedicated to ensuring equitable health in all communities. Through collaboration with numerous organizations, and powered by millions of volunteers, we fund innovative research, advocate for the public's health and share lifesaving resources. The Dallas-based organization has been a leading source of health information for nearly a century. Connect with us on heart.org, Facebook, Twitter or by calling 1-800-AHA-USA1.

American Heart Association

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