Gastrointestinal symptoms not linked to later autism

August 22, 2002

Children with autism are no more likely than children without autism to have had gastrointestinal disorders, finds a study in this week's BMJ.

Researchers at Boston University identified 96 children with autism from the UK General Practice Research Database between 1988 and 1999. Each case was matched with up to five children without autism. They also considered the time relation between measles, mumps, and rubella vaccination and the onset of gastrointestinal symptoms among the cases.

They found no increase in a history of gastrointestinal disorders, coeliac disease, food intolerance, or recurrent gastrointestinal symptoms among children with autism compared with those without autism. They also found no temporal association between measles, mumps, and rubella vaccination and the onset of gastrointestinal symptoms in children with autism.

The authors cannot exclude the possibility that some children in the study had subclinical gastrointestinal symptoms before their presentation with autistic behaviour. However, the children described by Wakefield and colleagues had symptomatic gastrointestinal disease.

They also cannot exclude the possibility that severe gastrointestinal disease may be associated with the development of autism in certain individuals. However, their results indicate that if this occurs, it is likely to be uncommon.

"Our results are consistent with those of other studies in providing evidence against a substantial association between gastrointestinal illness in children and the later development of autism," they conclude.


Related Autism Articles from Brightsurf:

Autism-cholesterol link
Study identifies genetic link between cholesterol alterations and autism.

National Autism Indicators Report: the connection between autism and financial hardship
A.J. Drexel Autism Institute released the 2020 National Autism Indicators Report highlighting the financial challenges facing households of children with autism spectrum disorder (ASD), including higher levels of poverty, material hardship and medical expenses.

Autism risk estimated at 3 to 5% for children whose parents have a sibling with autism
Roughly 3 to 5% of children with an aunt or uncle with autism spectrum disorder (ASD) can also be expected to have ASD, compared to about 1.5% of children in the general population, according to a study funded by the National Institutes of Health.

Adulthood with autism
The independence that comes with growing up can be scary for any teenager, but for young adults with autism spectrum disorder and their caregivers, the transition from adolescence to adulthood can seem particularly daunting.

Brain protein mutation from child with autism causes autism-like behavioral change in mice
A de novo gene mutation that encodes a brain protein in a child with autism has been placed into the brains of mice.

Autism and theory of mind
Theory of mind, or the ability to represent other people's minds as distinct from one's own, can be difficult for people with autism.

Potential biomarker for autism
A study of young children with autism spectrum disorder published in JNeurosci reveals altered brain waves compared to typically developing children during a motor control task.

Autism often associated with multiple new mutations
Most autism cases are in families with no previous history of the disorder.

State laws requiring autism coverage by private insurers led to increases in autism care
A new study led by researchers at the Johns Hopkins Bloomberg School of Public Health has found that the enactment of state laws mandating coverage of autism spectrum disorder (ASD) was followed by sizable increases in insurer-covered ASD care and associated spending.

Autism's gender patterns
Having one child with autism is a well-known risk factor for having another one with the same disorder, but whether and how a sibling's gender influences this risk has remained largely unknown.

Read More: Autism News and Autism Current Events is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to