Single-step nasal spray naloxone easiest to deliver according to new research

August 29, 2018

BINGHAMTON, N.Y. - Single-step nasal spray naloxone is the easiest to deliver, according to new research led by faculty at Binghamton University, State University at New York.

Expanded access to naloxone, also known as Narcan®, has been identified as a key intervention for reducing opioid-related deaths. However, there is more than one way to administer it and it is unknown which method is most successful when administered by community members.

William Eggleston, clinical assistant professor at the School of Pharmacy and Pharmaceutical Sciences at Binghamton University, was interested in knowing how successfully community members could administer naloxone after basic video training.

"I'm studying things like which type of naloxone should we give to members of the community, and what is the best way to distribute that naloxone," Eggleston said.

In collaboration with SUNY Upstate Medical University in Syracuse, N.Y., Eggleston conducted a study to estimate and compare the rate of successful administration and the time to successful administration by community members for single-step nasal spray, multi-step atomized nasal spray and intramuscular simulated naloxone.

Over a three-day period at the New York State Fair in Syracuse, 138 adults with no prior naloxone training were asked to watch a two-minute video demonstrating how to administer naloxone via one of the three methods - two nasal sprays and one intramuscular - and then to administer the naloxone to a mannequin using their randomly selected method.

After the video training, participants were able to administer the single-step nasal spray naloxone with a higher rate of success than the intramuscular naloxone, and also to administer the single-step nasal spray naloxone more rapidly than either the multi-step atomized spray or the intramuscular naloxone. This information is important for community naloxone programs across the United States.

"With training, nasal sprays in general had a higher degree of success than the shot," Eggleston said. "Even if it seemed to us it was a no-brainer that we should be using nasal sprays, we had no data before, so now we have some to support that."

The study, "A Randomized Usability Assessment of Simulated Naloxone Administration by Community Members," was published in the journal Addiction in August.
-end-


Binghamton University

Related Training Articles from Brightsurf:

Online training helps preemies
An international team of researchers has now found that computerised training can support preterm children's academic success.

Assessing training in health disparities
This survey study described and compared the curriculum on health disparities from the perspective of program directors and perceptions of training among internal medicine residents.

Music training may not make children smarter after all
Music training does not have a positive impact on children's cognitive skills, such as memory, and academic achievement, such as maths, reading or writing, according to a study published in Memory & Cognition.

Traditional strength training vs jump training for physically inactive young adults
The aim of this study was to compare the effects of 4-weeks of Traditional Resistance Training versus Plyometric Jump Training programs on the muscular fitness of sedentary and physically inactive participants.

Strength training benefits patients with cirrhosis
Three hours of weekly strength training combined with protein supplements leads to both bigger and stronger muscles in patients with cirrhosis.

Mindfulness training shows promise for people with MS
New research suggests mindfulness training may help multiple sclerosis patients in two very different ways: regulating negative emotions and improving processing speed.

The retention effect of training
Company training increases the loyalty of its employees. Loyalty also increases if the training improves the employees' chances on the labour market.

Training the mind in resilience
Two new studies from University of Miami researchers found that offering mindfulness training in high-demand settings bolsters attention and resilience.

Memory training builds upon strategy use
Researchers from Åbo Akademi University, Finland, and Umeå University, Sweden, have for the first time obtained clear evidence of the important role strategies have in memory training.

One or the other: Why strength training might come at the expense of endurance muscles
The neurotransmitter brain-derived neurotrophic factor (BDNF) acts in the muscle, so that during strength training endurance muscle fiber number is decreased.

Read More: Training News and Training Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.