Kumamoto University's Dr. Hirofumi Kai wins research grant from Alport Syndrome Foundation

August 30, 2016

A research group from Kumamoto University, Japan has been awarded an international research grant from the U.S.-based Alport Syndrome Foundation. This marks the first time the foundation has awarded funding to a Japanese research group.

Alport syndrome (AS) is a progressive genetic kidney disease with high risk for kidney failure and often requires dialysis treatment or kidney transplant. For those with the disease, symptoms may not appear soon after birth but they usually emerge at some point during their lifetime. In previous research working toward inhibiting the development of AS, Professor Hirofumi Kai and his team at Kumamoto University focused on the point at which symptoms began progressing. Their findings were published in the Jan. 2016 issue of the Journal of the American Society of Nephrology, one of the top journals for kidney studies, and photos from the study were featured on the cover.

The Alport Syndrome Research Funding Program began in 2010 and has selected between one to two projects each year for funding. This year, two projects were selected for the award out of ten applications from around the world. Professor Kai's winning research proposal is entitled, "Search for therapeutic reagents by modeling Alport syndrome in mice and humans" and will receive 50,000 USD per year for the next two years.

In 2013, Kumamoto University was selected by Japan's Ministry of Education, Culture, Sports, Science and Technology for "The Program for Promoting the Enhancement of Research Universities" and has since been strengthening its international collaborative research programs. These collaborations at Kumamoto University are expected to develop even further in the coming years with increasing overseas grant acquisitions.
-end-
Visit the Alport Syndrome Foundation website to learn more about Alport syndrome, the research program, and this year's funding recipients. http://alportsyndrome.org/research/asf-research-program/

Kumamoto University

Related Disease Articles from Brightsurf:

CLCN6 identified as disease gene for a severe form of lysosomal neurodegenerative disease
A mutation in the CLCN6 gene is associated with a novel, particularly severe neurodegenerative disorder.

Cellular pathway of genetic heart disease similar to neurodegenerative disease
Research on a genetic heart disease has uncovered a new and unexpected mechanism for heart failure.

Mechanism linking gum disease to heart disease, other inflammatory conditions discovered
The link between periodontal (gum) disease and other inflammatory conditions such as heart disease and diabetes has long been established, but the mechanism behind that association has, until now, remained a mystery.

Potential link for Alzheimer's disease and common brain disease that mimics its symptoms
A new study by investigators from Brigham and Women's Hospital uncovered a group of closely related genes that may capture molecular links between Alzheimer's disease and Limbic-predominant Age-related TDP-43 Encephalopathy, or LATE, a recently recognized common brain disorder that can mimic Alzheimer's symptoms.

Antioxidant agent may prevent chronic kidney disease and Parkinson's disease
Researchers from Osaka University developed a novel dietary silicon-based antioxidant agent with renoprotective and neuroprotective effects.

Tools used to study human disease reveal coral disease risk factors
In a study published in Scientific Reports, a team of international researchers led by University of Hawai'i (UH) at Mānoa postdoctoral fellow Jamie Caldwell used a statistical technique typically employed in human epidemiology to determine the ecological risk factors affecting the prevalence of two coral diseases--growth anomalies, abnormalities like coral tumors, and white syndromes, infectious diseases similar to flesh eating bacteria.

Disease-aggravating mutation found in a mouse model of neonatal mitochondrial disease
The new mitochondrial DNA (mtDNA) variant drastically speeds up the disease progression in a mouse model of GRACILE syndrome.

Human longevity largest study of its kind shows early detection of disease & disease risks
Human Longevity, Inc. (HLI) announced the publication of a ground-breaking study in the journal Proceedings of the National Academy of Sciences (PNAS).

30-year study identifies need of disease-modifying therapies for maple syrup urine disease
A new study analyzes 30 years of patient data and details the clinical course of 184 individuals with genetically diverse forms of Maple Syrup Urine Disease (MSUD), which is among the most volatile and dangerous inherited metabolic disorders.

Long-dormant disease becomes most dominant foliar disease in New York onion crops
Until recently, Stemphylium leaf blight has been considered a minor foliar disease as it has not done much damage in New York since the early 1990s.

Read More: Disease News and Disease Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.