Nav: Home

Defend or grow? These plants do both

August 30, 2016

From natural ecosystems to farmers' fields, plants face a dilemma of energy use: outgrow and outcompete their neighbors for light, or defend themselves against insects and disease.

But what if you could grow a plant that does both at the same time?

A team of researchers at Michigan State University is the first to accomplish that feat, and the breakthrough could have fruitful implications for farmers trying to increase crop yields and feed the planet's growing population.

"We've created a genetic combination that no one has ever made before," said plant scientist Gregg Howe, MSU Foundation professor of biochemistry and molecular biology, who led the study. "We got an unexpected outcome, and these results turned out to be quite interesting. This research may open up new ways of thinking about how valuable plant traits can be combined in novel and useful ways."

In a paper published in the current issue of Nature Communications, Howe, a member of the Plant Research Lab at MSU, and his team describe how they were able to modify an Arabidopsis plant -- a relative of mustard -- by "knocking out" both a defense hormone repressor and a light receptor in the plant. This genetic alteration allowed the plant to grow fast and defend itself from insects at the same time.

"Normally plants can't do both. It is generally thought that plants have a fixed energy budget, and they put that energy toward one process at the expense of other processes. There is a tradeoff," Howe said. "But in our plant there's not an energy tradeoff. We've upset that paradigm."

Plants in nature and agriculture that are stressed by drought, diseases or insects will mount defensive responses, and at the same time will typically stop growing or grow more slowly. Likewise, when plants are subject to conditions where they must grow fast, such as competing for light when neighbors encroach -- called the shade avoidance response -- their defenses become compromised.

"This is the growth-defense concept: you promote defense but at the same time you give up growth," Howe said. "More growth equals less defense, more defense equals less growth. But we've done some genetic trickery to get a plant to do both."

The implications of this breakthrough could have major practical applications in agriculture as the research continues to develop. If the results of the study can be replicated in crop plants, the work could have direct benefits for farmers trying to feed a world population that is expected to reach nine billion by the year 2050. According to the Bill and Melinda Gates foundation, food production will need to increase by 70 percent to 100 percent to feed that growing population.

"But can we do this in a crop plant -- that is something we want to pursue," said Howe of the next steps in their research.

One common way for farmers to increase crop yields is to increase the density of their plantings. This leaves row crops -- such as corn or soybeans -- competing against one another for light, and in doing so lowering their defenses and leaving them susceptible to infestation and disease. To counter these risks of growing densely planted crops, farmers must apply pesticides.

"If we can design better corn plants, you could pack them in and they would be well defended all the time without pesticides -- that's one potential direction this research could go," Howe said. "The growth-defense tradeoffs we've observed aren't something found only in Arabidopsis, it's found in all plants. The hormone and light response pathways we've modified are in all the major crops."

The research, funded in part by the U.S. Department of Energy, has revealed a connection in plants between the roles played by defense signaling and light signaling, processes that activate genes in response to environmental stresses. Eye-opening results such as these came as a surprise even to the research team.

"Initially I was skeptical of the research idea and thought 'that's crazy.' But we took the risk and it proved to pay off," Howe said. "We've grown a plant that can have its cake and eat it too. The fact that it can be done is remarkable."
Collaborating with Howe were MSU scientists Tom Sharkey and David Kramer, and Georg Jander at Cornell University.

Michigan State University

Related Molecular Biology Articles:

Combined molecular biology test is the first to distinguish benign pancreatic lesions
When performed in tandem, two molecular biology laboratory tests distinguish, with near certainty, pancreatic lesions that mimic early signs of cancer but are completely benign.
Behavioral biology: Ripeness is all
In contrast to other members of the Drosophila family, the spotted-wing fly D. suzukii deposits its eggs in ripe fruits.
Molecular biology: Fingerprinting cell identities
Every cell has its own individual molecular fingerprint, which is informative for its functions and regulatory states.
A systems biology perspective on molecular cytogenetics
Professor Henry Heng's team, from the medical school at Wayne State University, has published a perspective article titled A Systems Biology Perspective on Molecular Cytogenetics to address the issue.
Cell biology: Take the mRNA train
Messenger RNAs bearing the genetic information for the synthesis of proteins are delivered to defined sites in the cell cytoplasm by molecular motors.
Gravitational biology
Akira Kudo at Tokyo Institute of Technology(Tokyo Tech) and colleagues report in Scientific Reports, December 2016, that live-imaging and transcriptome analysis of medaka fish transgenic lines lead to immediate alteration of cells responsible for bone structure formation.
Biology's 'breadboard'
Understanding how the nervous system of the roundworm C. elegans works will give insights into how our vastly more complex brains function and is the subject of a paper in Nature Methods.
Association for molecular pathology establishes new standard for clinical utility of molecular Dx
The Association for Molecular Pathology, the premier global, non-profit organization serving molecular diagnostic professionals, today announced a new report that addresses the challenges in defining the clinical utility of molecular diagnostics for inherited diseases and cancer.
The use of Camelid antibodies for structural biology
The use of Camelid antibodies has important implications for future development of reagents for diagnosis and therapeutics in diseases involving a group of enzymes called serine proteases.
New tools to manipulate biology
Chemistry has provided many key tools and techniques to the biological community in the last twenty years.

Related Molecular Biology Reading:

Best Science Podcasts 2019

We have hand picked the best science podcasts for 2019. Sit back and enjoy new science podcasts updated daily from your favorite science news services and scientists.
Now Playing: TED Radio Hour

Moving Forward
When the life you've built slips out of your grasp, you're often told it's best to move on. But is that true? Instead of forgetting the past, TED speakers describe how we can move forward with it. Guests include writers Nora McInerny and Suleika Jaouad, and human rights advocate Lindy Lou Isonhood.
Now Playing: Science for the People

#527 Honey I CRISPR'd the Kids
This week we're coming to you from Awesome Con in Washington, D.C. There, host Bethany Brookshire led a panel of three amazing guests to talk about the promise and perils of CRISPR, and what happens now that CRISPR babies have (maybe?) been born. Featuring science writer Tina Saey, molecular biologist Anne Simon, and bioethicist Alan Regenberg. A Nobel Prize winner argues banning CRISPR babies won’t work Geneticists push for a 5-year global ban on gene-edited babies A CRISPR spin-off causes unintended typos in DNA News of the first gene-edited babies ignited a firestorm The researcher who created CRISPR twins defends...