Possible link found between hypothyroidism and glaucoma in men

September 01, 2004

SAN FRANCISCO--A significant association was found between hypothyroidism and open-angle glaucoma, according to a study appearing in the September issue of Ophthalmology, the clinical journal of the American Academy of Ophthalmology. The relationship between the two has been disputed in prior studies.

Glaucoma, a leading cause of blindness in the United States, is a condition in which the optic nerve is damaged. It can be associated with elevated pressure inside the eye and can lead to vision loss. According to the National Eye Institute, nearly 2.3 million people in the United States have open-angle glaucoma, the most common form. Hypothyroidism is a common endocrine condition, affecting approximately five percent of the population.

Nearly 600 male patients with newly diagnosed glaucoma were seen at Veterans Affairs Medical Center, in Birmingham, Ala from 1997 to 2001. They were compared with nearly 6,000 non-glaucoma male patients as the control group. Of the patients with glaucoma, 6.44 percent had a prior diagnosis of hypothyroidism, compared with 3.97 percent of the control group.

"This is the first study to show the association of hypothyroidism with glaucoma in a convincing manner," said Academy spokesperson Louis B. Cantor, MD, the Jay C. and Lucile L. Kahn Professor of Glaucoma Research and education director of glaucoma service at Indiana University School of Medicine's ophthalmology department in Indianapolis. "Now that an association has been demonstrated, hypothyroidism should be added to the list of potential risk factors to consider."

"Hypothyroidism, a treatable, but often undiagnosed condition, may be related to the development of glaucoma," said study author, Christopher A. Girkin, MD, an associate professor of ophthalmology at the University of Alabama in Birmingham. "Additional research is needed to determine the significance of hypothyroidism in the development of glaucoma and whether thyroid replacement therapy would have a significant effect on glaucomatous progression."
-end-
This study was supported by the National Institutes of Health, and the EyeSight Foundation of Alabama.

The American Academy of Ophthalmology is the world's largest association of eye physicians and surgeons--Eye M.D.s--with more than 27,000 members. For more information about eye health care, visit the Academy's partner Web site, the Medem Network, at www.medem.com/eyemd. To find an Eye M.D. in your area, visit the Academy's Web site at www.aao.org.

American Academy of Ophthalmology

Related Glaucoma Articles from Brightsurf:

Monitoring glaucoma at home
Glaucoma is a chronic condition that affects cells at the back of the eye.

Study finds novel mechanism that may confer protection against glaucoma
A team of researchers from LSU Health New Orleans Neuroscience Center of Excellence and the University of Copenhagen provides the first evidence that patients with ocular hypertension may exhibit superior antioxidant protection that promotes resistance to the elevated intraocular pressure associated with glaucoma.

AI-supported test for very early signs of glaucoma progression
A new test can detect glaucoma progression 18 months earlier than the current gold standard method, according to results from a UCL-sponsored clinical trial.

New method gives glaucoma researchers control over eye pressure
Neuroscientists have developed a new method that permits continuous regulation of eye pressure without damage, becoming the first to definitively prove pressure in the eye is sufficient to cause and explain glaucoma.

Glaucoma care in prison inmates
Data fromĀ 82 prison inmates treated in a glaucoma clinic at an academic hospital were used in this observational study to report on how treatment and follow-up, including medication adherence, were are managed.

New glaucoma test to help prevent blindness
Researchers have identified 107 genes that increase a person's risk of developing the eye disease glaucoma, and now developed a genetic test to detect those at risk of going blind from it.

Air pollution linked to higher glaucoma risk
Living in a more polluted area is associated with a greater likelihood of having glaucoma, a debilitating eye condition that can cause blindness, finds a new UCL-led study in the UK.

Long-term statin use associated with lower glaucoma risk
A new study brings the connection between statin use and risk of glaucoma into sharper focus.

Health burden of glaucoma has risen worldwide
The health burden of glaucoma has continuously increased around the globe in the past 25 years, according to an Acta Opthalmologica study.

UAlberta scientists first to pinpoint a cause of pigmentary glaucoma
An international team of researchers has identified a gene responsible for the onset of pigmentary glaucoma, which may lead to new therapies for the condition.

Read More: Glaucoma News and Glaucoma Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.