Melatonin may help treat blood cancersSeptember 01, 2017
Researchers have examined the potential benefits of melatonin, a hormone made by a small gland in the brain, for treating blood cancers such as leukemia and lymphoma. They point to evidence that melatonin boosts the immune response against cancer cells, inhibits cancer cell growth, and protects healthy cells from the toxic effects of chemotherapy.
Because melatonin is also involved in regulating circadian rhythms, which help coordinate and synchronize internal body functions, timing of melatonin treatments may be critical to their anticancer effects.
"We hope this information will be helpful in the design of studies related to the therapeutic efficacy of melatonin in blood cancers," said Dr. Yang Yang, senior author of the British Journal of Pharmacology article. "Also, clarifying the mechanisms of melatonin's anticancer actions will help facilitate future basic research and clinical applications."
Related Leukemia Articles:
Researchers at The Australian National University (ANU) are working on a new treatment for an aggressive type of leukemia that outperforms standard chemotherapies.
UT Health San Antonio researchers discovered epigenetic changes that contribute to one-fifth of cases of acute myeloid leukemia (AML), an aggressive cancer that arises out of the blood-forming cells in bone marrow.
Watanabe-Smith's research, published today in the journal Oncotarget, sought to better understand one 'typo' in a standard leukemia assay, or test.
Scientists have discovered the genetic driver of a lethal childhood leukemia that affects newborns and infants and identified a targeted molecular therapy that halts the proliferation of leukemic cells.
Cancer researchers at the University of Cincinnati College of Medicine have found an obesity-associated protein's role in leukemia development and drug response which could lead to more effective therapies for the illness.
Dr. Irmela Jeremias from Helmholtz Zentrum München and her colleagues have succeeded in finding a small population of inactive leukemia cells that is responsible for relapse of the disease.
A team of UCLA bioengineers has demonstrated that its technology may go a long way toward overcoming the challenges of treatment for acute lymphoblastic leukemia, among the most common types of cancer in children, and has the potential to help doctors personalize drug doses.
Cancer cells need a lot of energy in order to divide without limits.
For the first time, researchers have discovered that some leukemia cells harvest energy resources from normal cells during chemotherapy, helping the cancer cells not only to survive, but actually thrive, after treatment.
In this issue of JCI Insight, Nicholas Chiorazzi and colleagues at the Feinstein Institute for Medical Research sought to understand a model of chronic lymphocytic leukemia in which patient cancer cells are transplanted into immunocompromised mice.
Related Leukemia Reading:
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Philadelphia, 1959: A scientist scrutinizing a single human cell under a microscope detects a missing piece of DNA. That scientist, David Hungerford, had no way of knowing that he had stumbled upon the starting point of modern cancer research― the Philadelphia chromosome. It would take doctors and researchers around the world more than three decades to unravel the implications of this landmark discovery. In 1990, the Philadelphia chromosome was recognized as the sole cause of a deadly blood cancer, chronic myeloid leukemia, or CML. Cancer research would never be the same. Tens of thousands of Americans are living with adult leukemia, a cancer of the white blood cells. Adult leukemia, which is really a group of diseases, can be a baffling condition for patients and families to understand, and finding targeted information on individual conditions can be difficult.In straightforward, non-technical language, Adult Leukemia: A Comprehensive Guide for Patients and Families gives those living with leukemia the skills and resources to meet their needs for information and support. It addresses:
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Selected from the world’s leading comprehensive cancer textbook, this tightly focused resource provides you with the practical, cutting-edge information you need to provide the best cancer care to each patient. Lymphomas and Leukemias: Cancer: Principles & Practice of Oncology, 10th Edition, offers a complete and balanced view of this rapidly changing field, meeting the needs of oncology/hematology practitioners, fellows, and others who need an in-depth understanding of leukemias and lymphomas. The print reference gives you the solid, dependable guidance you have come to expect from... View Details
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Leukemia, or cancer of the blood or bone marrow, occurs in both acute and chronic forms. While the exact causes of the disease are not known, several risk factors have been identified. There are four major types of leukemia: acute myeloid leukemia (AML), chronic myeloid leukemia (CML), acute lymphoid leukemia (ALL), and chronic lymphoid leukemia (CLL), and treatments include chemotherapy, radiation, and bone marrow transplants. Leukemia discusses the science of leukemia, theories about its causes, the history of the disease, and the current treatments and how they work. View Details
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Johns Hopkins Patients' Guide to Leukemia is a concise, easy-to-follow "how to" guide that puts you on a path to wellness by explaining leukemia treatment from start to finish. It guides you through the overwhelming maze of treatment decisions, simplifies the complicated schedule that lies ahead, and performs the task of putting together your plan of care in layman's terms. Empower yourself with accurate, understandable information that will give you the ability to confidently participate in the decision making about your care and treatment.
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Are you looking for a unique gift for a friend or family member fighting Leukemia?
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110 pages6x9 inchesExcellent and thick bindingDurable white paperMatte-finished cover for a professional look
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Leukemia (WHAT YOU NEED TO KNOW Book 7)
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Estimated new cases and deaths from leukemia in the United States in 2012:
New cases: 47,150
Deaths: 23,540 View Details