Nav: Home

Melatonin may help treat blood cancers

September 01, 2017

Researchers have examined the potential benefits of melatonin, a hormone made by a small gland in the brain, for treating blood cancers such as leukemia and lymphoma. They point to evidence that melatonin boosts the immune response against cancer cells, inhibits cancer cell growth, and protects healthy cells from the toxic effects of chemotherapy.

Because melatonin is also involved in regulating circadian rhythms, which help coordinate and synchronize internal body functions, timing of melatonin treatments may be critical to their anticancer effects.

"We hope this information will be helpful in the design of studies related to the therapeutic efficacy of melatonin in blood cancers," said Dr. Yang Yang, senior author of the British Journal of Pharmacology article. "Also, clarifying the mechanisms of melatonin's anticancer actions will help facilitate future basic research and clinical applications."
-end-


Wiley

Related Leukemia Articles:

New leukemia treatment outperforms standard chemotherapies
Researchers at The Australian National University (ANU) are working on a new treatment for an aggressive type of leukemia that outperforms standard chemotherapies.
Team uncovers novel epigenetic changes in leukemia
UT Health San Antonio researchers discovered epigenetic changes that contribute to one-fifth of cases of acute myeloid leukemia (AML), an aggressive cancer that arises out of the blood-forming cells in bone marrow.
Gene mutations cause leukemia, but which ones?
Watanabe-Smith's research, published today in the journal Oncotarget, sought to better understand one 'typo' in a standard leukemia assay, or test.
Halting lethal childhood leukemia
Scientists have discovered the genetic driver of a lethal childhood leukemia that affects newborns and infants and identified a targeted molecular therapy that halts the proliferation of leukemic cells.
Obesity-associated protein could be linked to leukemia development
Cancer researchers at the University of Cincinnati College of Medicine have found an obesity-associated protein's role in leukemia development and drug response which could lead to more effective therapies for the illness.
Tracking down therapy-resistant leukemia cells
Dr. Irmela Jeremias from Helmholtz Zentrum München and her colleagues have succeeded in finding a small population of inactive leukemia cells that is responsible for relapse of the disease.
Personalizing chemotherapy to treat pediatric leukemia
A team of UCLA bioengineers has demonstrated that its technology may go a long way toward overcoming the challenges of treatment for acute lymphoblastic leukemia, among the most common types of cancer in children, and has the potential to help doctors personalize drug doses.
Putting a brake on leukemia cells
Cancer cells need a lot of energy in order to divide without limits.
Study provides new clues to leukemia resurgence after chemotherapy
For the first time, researchers have discovered that some leukemia cells harvest energy resources from normal cells during chemotherapy, helping the cancer cells not only to survive, but actually thrive, after treatment.
Improving models of chronic lymphocytic leukemia
In this issue of JCI Insight, Nicholas Chiorazzi and colleagues at the Feinstein Institute for Medical Research sought to understand a model of chronic lymphocytic leukemia in which patient cancer cells are transplanted into immunocompromised mice.

Related Leukemia Reading:

Childhood Leukemia: A Guide for Families, Friends & Caregivers
by Nancy Keene (Author)

Approximately 4,500 children and teens are diagnosed with leukemia in the United States and Canada each year. The illness and its treatment can have a devastating effect on family, friends, classmates, and the larger community. This newly updated edition of Childhood Leukemia contains the information and support parents need during this difficult time, including:New treatments such as immunotherapy, tailoring drugs dosages to children's genetic profiles, and ways to deal with side effects.Advice on how to cope with procedures, hospitalization, school, family, and financial issues.Tips for... View Details


The Philadelphia Chromosome: A Genetic Mystery, a Lethal Cancer, and the Improbable Invention of a Lifesaving Treatment
by Jessica Wapner (Author), Robert A. Weinberg PhD (Foreword)

Philadelphia, 1959: A scientist scrutinizing a single human cell under a microscope detects a missing piece of DNA. That scientist, David Hungerford, had no way of knowing that he had stumbled upon the starting point of modern cancer research― the Philadelphia chromosome. It would take doctors and researchers around the world more than three decades to unravel the implications of this landmark discovery. In 1990, the Philadelphia chromosome was recognized as the sole cause of a deadly blood cancer, chronic myeloid leukemia, or CML. Cancer research would never be the same.
View Details


Leukemia: From Diagnosis to Winning the Battle
by Ryan Woelfel (Author), MD Robert Brian Berryman (Foreword), Connie Kouba (Foreword)

You’re a young 24-year-old, three months out of college, working as a Systems Engineer for a company, at a salary you named. You’re engaged to be married in a month, closing on a house and on top of the world, and that world has just been turned upside down. You’ve just been diagnosed with cancer – leukemia. Now what? So much uncertainty. In fact, the only certainty is just how uncertain everything is. But wait. Maybe there’s a reason for all this. Maybe some underlying purpose. Maybe this was all part of some greater plan.

This is the personal account of one... View Details


Childhood Leukemia: A Guide for Families, Friends & Caregivers (Childhood Cancer Guides)
by Nancy Keene (Author)

Approximately 3,300 children are diagnosed with leukemia in the United States each year. The illness and its treatment can have a devastating effect on family, friends, schoolmates, and the larger community. This newly updated edition of Childhood Leukemia contains the information and support parents need during this difficult time. Author Nancy Keene provides parents and family members with: • Updates on treatment, including stem cell transplants, information about tailoring drugs dosages to children’s genetic profiles, and new methods for dealing with side effects. • Practical advice... View Details


Leukemia (WHAT YOU NEED TO KNOW Book 7)

Definition of leukemia: Cancer that starts in blood-forming tissue such as the bone marrow and causes large numbers of blood cells to be produced and enter the bloodstream.
Estimated new cases and deaths from leukemia in the United States in 2012:

New cases: 47,150

Deaths: 23,540 View Details


Leukemia (Emerging Cancer Therapeutics V2 I2)
by Uday R. Popat MD MRCP FRCPath FACP (Editor), Jame Abraham MD FACP (Editor)

"This issue of Emerging Cancer Therapeutics provides a comprehensive review for practitioners on the current status of leukemia treatment. Leukemia treatment has undergone major change over the course of the past few years and Leukemia addresses current best practices in the light of the most recent evidence.

With contributions from experts across the US and Canada, Leukemia details the current management of different types of leukemia and reviews new therapies in development for various forms of acute leukemia, chronic leukemia, myelodysplastic syndrome, and... View Details


100 Questions & Answers About Leukemia
by Edward D. Ball (Author), Alex Kagan (Author)

EMPOWER YOURSELF!

Whether you're a newly diagnosed patient, survivor, or a friend, relative or caregiver, 100 Questions & Answers About Leukemia offers support and guidance. Now in its third edition, 100 Questions & Answers About Leukemia continues the successful doctor-patient collaboration, providing authoritative, practical answers to your questions regarding diagnostic testing, treatment options, clinical trials and much more.

Written by a leukemia survivor and a prominent physician specializing in treatment of leukemia, this book is an invaluable resource for anyone coping... View Details


Leukemia: True Survival Stories (Powerful Medicine)
by Sandra Markle (Author)

- A young girl receives injections of chemotherapy to kill the cancerous white blood cells in her body.
- An eleven-year-old boy undergoes a transplant of stem cells to help his body make new, healthy blood cells.
- A new machine gives scientists a way to quickly check for and diagnose leukemia.

That's powerful medicine!

Explore the power of medicine through the true stories of two young people who survived life-threatening leukemia. Find out how doctors use the latest medical breakthroughs to save patients who have the faulty blood cells that cause... View Details


NCCN Guidelines for Patients®: Chronic Myeloid Leukemia, 2018
by National Comprehensive Cancer Network® (NCCN®) (Author)

From the medical leaders of 27 leading cancer centers united under the National Comprehensive Cancer Network® (NCCN®), comes this essential guide to chronic myeloid leukemia (CML). Adapted from clinical treatment guidelines used by physicians and oncology professionals around the world, these NCCN Guidelines for Patients® are packed with the latest information, treatment innovations, and resources. Each patient-friendly chapter prepares patients and caregivers to talk with their doctors and make treatment decisions. Let this authoritative handbook be your guide! Part 1 – CML basics:... View Details


Leukemia (USA Today Health Reports: Diseases and Disorders)
by Connie Goldsmith (Author)

Describes leukemia, including its symptoms, how it is diagnosed, the different types, and current treatments, and discusses future research into leukemia treatments and the controversies behind them. View Details

Best Science Podcasts 2018

We have hand picked the best science podcasts for 2018. Sit back and enjoy new science podcasts updated daily from your favorite science news services and scientists.
Now Playing: TED Radio Hour

Inspire To Action
What motivates us to take up a cause, follow a leader, or create change? This hour, TED speakers explore stories of inspirational leadership, and what makes some movements more successful than others. Guests include high school history teacher Diane Wolk-Rogers, writer and behavioral researcher Simon Sinek, 2016 Icelandic presidential candidate Halla Tómasdóttir, professor of leadership Jochen Menges, and writer and activist Naomi Klein.
Now Playing: Science for the People

#474 Appearance Matters
This week we talk about appearance, bodies, and body image. Why does what we look like affect our headspace so much? And how do we even begin to research a topic as personal and subjective as body image? To try and find out, we speak with some of the researchers at the Centre for Appearance Research (CAR) at the University of the West of England in Bristol. Psychology Professor Phillippa Diedrichs walks us through body image research, what we know so far, and how we know what we know. Professor of Appearance and Health Psychology Diana Harcourt talks about visible...