Nav: Home

Melatonin may help treat blood cancers

September 01, 2017

Researchers have examined the potential benefits of melatonin, a hormone made by a small gland in the brain, for treating blood cancers such as leukemia and lymphoma. They point to evidence that melatonin boosts the immune response against cancer cells, inhibits cancer cell growth, and protects healthy cells from the toxic effects of chemotherapy.

Because melatonin is also involved in regulating circadian rhythms, which help coordinate and synchronize internal body functions, timing of melatonin treatments may be critical to their anticancer effects.

"We hope this information will be helpful in the design of studies related to the therapeutic efficacy of melatonin in blood cancers," said Dr. Yang Yang, senior author of the British Journal of Pharmacology article. "Also, clarifying the mechanisms of melatonin's anticancer actions will help facilitate future basic research and clinical applications."
-end-


Wiley

Related Leukemia Articles:

New leukemia treatment outperforms standard chemotherapies
Researchers at The Australian National University (ANU) are working on a new treatment for an aggressive type of leukemia that outperforms standard chemotherapies.
Team uncovers novel epigenetic changes in leukemia
UT Health San Antonio researchers discovered epigenetic changes that contribute to one-fifth of cases of acute myeloid leukemia (AML), an aggressive cancer that arises out of the blood-forming cells in bone marrow.
Gene mutations cause leukemia, but which ones?
Watanabe-Smith's research, published today in the journal Oncotarget, sought to better understand one 'typo' in a standard leukemia assay, or test.
Halting lethal childhood leukemia
Scientists have discovered the genetic driver of a lethal childhood leukemia that affects newborns and infants and identified a targeted molecular therapy that halts the proliferation of leukemic cells.
Obesity-associated protein could be linked to leukemia development
Cancer researchers at the University of Cincinnati College of Medicine have found an obesity-associated protein's role in leukemia development and drug response which could lead to more effective therapies for the illness.
Tracking down therapy-resistant leukemia cells
Dr. Irmela Jeremias from Helmholtz Zentrum München and her colleagues have succeeded in finding a small population of inactive leukemia cells that is responsible for relapse of the disease.
Personalizing chemotherapy to treat pediatric leukemia
A team of UCLA bioengineers has demonstrated that its technology may go a long way toward overcoming the challenges of treatment for acute lymphoblastic leukemia, among the most common types of cancer in children, and has the potential to help doctors personalize drug doses.
Putting a brake on leukemia cells
Cancer cells need a lot of energy in order to divide without limits.
Study provides new clues to leukemia resurgence after chemotherapy
For the first time, researchers have discovered that some leukemia cells harvest energy resources from normal cells during chemotherapy, helping the cancer cells not only to survive, but actually thrive, after treatment.
Improving models of chronic lymphocytic leukemia
In this issue of JCI Insight, Nicholas Chiorazzi and colleagues at the Feinstein Institute for Medical Research sought to understand a model of chronic lymphocytic leukemia in which patient cancer cells are transplanted into immunocompromised mice.

Related Leukemia Reading:

The Philadelphia Chromosome: A Genetic Mystery, a Lethal Cancer, and the Improbable Invention of a Lifesaving Treatment
by Jessica Wapner (Author), Robert A. Weinberg PhD (Foreword)

Philadelphia, 1959: A scientist scrutinizing a single human cell under a microscope detects a missing piece of DNA. That scientist, David Hungerford, had no way of knowing that he had stumbled upon the starting point of modern cancer research― the Philadelphia chromosome. It would take doctors and researchers around the world more than three decades to unravel the implications of this landmark discovery. In 1990, the Philadelphia chromosome was recognized as the sole cause of a deadly blood cancer, chronic myeloid leukemia, or CML. Cancer research would never be the same.
View Details


Childhood Leukemia: A Guide for Families, Friends & Caregivers (Childhood Cancer Guides)
by Nancy Keene (Author)

Approximately 3,300 children are diagnosed with leukemia in the United States each year. The illness and its treatment can have a devastating effect on family, friends, schoolmates, and the larger community. This newly updated edition of Childhood Leukemia contains the information and support parents need during this difficult time. Author Nancy Keene provides parents and family members with: • Updates on treatment, including stem cell transplants, information about tailoring drugs dosages to children’s genetic profiles, and new methods for dealing with side effects. • Practical advice... View Details


Lymphomas and Leukemias: Cancer: Principles & Practice of Oncology, 10th edition
by Vincent T. DeVita Jr. MD (Author), Theodore S. Lawrence MD PhD (Author), Steven A. Rosenberg MD PhD (Author)

Selected from the world’s leading comprehensive cancer textbook, this tightly focused resource provides you with the practical, cutting-edge information you need to provide the best cancer care to each patient.  Lymphomas and Leukemias:  Cancer: Principles & Practice of Oncology, 10th Edition, offers a complete and balanced view of this rapidly changing field, meeting the needs of oncology/hematology practitioners, fellows, and others who need an in-depth understanding of leukemias and lymphomas. The print reference gives you the solid, dependable guidance you have come to expect from... View Details


Leukemia (The Biology of Cancer)
by Donna M. Bozzone (Author)

Leukemia, or cancer of the blood or bone marrow, occurs in both acute and chronic forms. While the exact causes of the disease are not known, several risk factors have been identified. There are four major types of leukemia: acute myeloid leukemia (AML), chronic myeloid leukemia (CML), acute lymphoid leukemia (ALL), and chronic lymphoid leukemia (CLL), and treatments include chemotherapy, radiation, and bone marrow transplants. Leukemia discusses the science of leukemia, theories about its causes, the history of the disease, and the current treatments and how they work. View Details


Johns Hopkins Patients' Guide to Leukemia
by Candis Morrison (Author), Charles L. Hesdorffer (Author)

Johns Hopkins Patients' Guide to Leukemia is a concise, easy-to-follow "how to" guide that puts you on a path to wellness by explaining leukemia treatment from start to finish. It guides you through the overwhelming maze of treatment decisions, simplifies the complicated schedule that lies ahead, and performs the task of putting together your plan of care in layman's terms. Empower yourself with accurate, understandable information that will give you the ability to confidently participate in the decision making about your care and treatment.


The Johns Hopkins Patients' Guide to... View Details


100 Questions & Answers About Leukemia
by Edward D. Ball (Author), Alex Kagan (Author)

EMPOWER YOURSELF!

Whether you're a newly diagnosed patient, survivor, or a friend, relative or caregiver, 100 Questions & Answers About Leukemia offers support and guidance. Now in its third edition, 100 Questions & Answers About Leukemia continues the successful doctor-patient collaboration, providing authoritative, practical answers to your questions regarding diagnostic testing, treatment options, clinical trials and much more.

Written by a leukemia survivor and a prominent physician specializing in treatment of leukemia, this book is an invaluable resource for anyone coping... View Details


Leukemia Messed With the Wrong Person: Blank Lined Journal - 6x9 - Funny Gift for Cancer Patient
by Passion Imagination Journals (Author)

Are you looking for a unique gift for a friend or family member fighting Leukemia?

Journaling is like therapy. This is a blank, lined journal that's perfect to write down thoughts during this stressful time. It has a humorous saying on the cover, which will help with a positive attitude.You will not be able to find a journal like this in other stores! Other features of this notebook include:
110 pages6x9 inchesExcellent and thick bindingDurable white paperMatte-finished cover for a professional look
This diary is a convenient and perfect size to carry anywhere for... View Details


Adult Leukemia: A Comprehensive Guide for Patients and Families
by Barb Lackritz (Author)

Tens of thousands of Americans are living with adult leukemia, a cancer of the white blood cells. Adult leukemia, which is really a group of diseases, can be a baffling condition for patients and families to understand, and finding targeted information on individual conditions can be difficult.In straightforward, non-technical language, Adult Leukemia: A Comprehensive Guide for Patients and Families gives those living with leukemia the skills and resources to meet their needs for information and support. It addresses:

Diagnosis and medical testsFinding, and successfully... View Details


Acute Leukemia: An Illustrated Guide to Diagnosis and Treatment
by Ashkan Emadi MD PhD (Editor), Judith E. Karp MD (Editor)

Acute Leukemia: An Illustrated Guide to Diagnosis and Treatment provides a comprehensive and concise visual reference on acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) seen in children and adults.


This book addresses all aspects of AML and ALL including their risk factors, cytogenetics and mutational characteristics, diagnoses, clinical management and prognoses which are imperative and challenging for medical students, residents, hematology and medical oncology fellows, and even community oncologists and hematologists. It presents complex information... View Details


Leukemia (WHAT YOU NEED TO KNOW Book 7)

Definition of leukemia: Cancer that starts in blood-forming tissue such as the bone marrow and causes large numbers of blood cells to be produced and enter the bloodstream.
Estimated new cases and deaths from leukemia in the United States in 2012:

New cases: 47,150

Deaths: 23,540 View Details

Best Science Podcasts 2017

We have hand picked the best science podcasts for 2017. Sit back and enjoy new science podcasts updated daily from your favorite science news services and scientists.
Now Playing: TED Radio Hour

Simple Solutions
Sometimes, the best solutions to complex problems are simple. But simple doesn't always mean easy. This hour, TED speakers describe the innovation and hard work that goes into achieving simplicity. Guests include designer Mileha Soneji, chef Sam Kass, sleep researcher Wendy Troxel, public health advocate Myriam Sidibe, and engineer Amos Winter.
Now Playing: Science for the People

#448 Pavlov (Rebroadcast)
This week, we're learning about the life and work of a groundbreaking physiologist whose work on learning and instinct is familiar worldwide, and almost universally misunderstood. We'll spend the hour with Daniel Todes, Ph.D, Professor of History of Medicine at The Johns Hopkins University, discussing his book "Ivan Pavlov: A Russian Life in Science."