Endometriosis increases risk of complications during pregnancy and deliverySeptember 13, 2017
(PHILADELPHIA) - A new meta-analysis shows that pregnant women with endometriosis are at greater risk for a host of complications during pregnancy and at delivery, including preterm birth and cesarean section. The study was published in the journal Fertility and Sterility.
"It's important that women with a history of endometriosis, and obstetricians caring for them, are aware of this association between prior endometriosis and higher risks of miscarriage, preterm birth, placenta previa, cesarean delivery and a baby small for gestational age," Vincenzo Berghella, M.D., Professor of Gynecology and Director of Maternal Fetal Medicine in the Department of Obstetrics and Gynecology at the Sidney Kimmel Medical College at Thomas Jefferson University. "These pregnancies deserve closer monitoring for these complications."
Endometriosis affects about 11 percent of women in the United States, is often diagnosed in the early reproductive years and is associated with endometrial tissue that travels and lodges in other parts of the body. Some of the symptoms include dagger-like abdominal pain, infertility and painful intercourse.
"Endometriosis is known to alter a woman's physiology in a way that could interfere with a number of stages of pregnancy," says Berghella. "From causing inflammation at the endometrium, to resisting the action of progesterone during implantation and throughout the pregnancy, there are a number of ways that endometriosis may affect the normal course of pregnancy."
Twenty four studies were included in the analysis comprising over a million women. The results show that women had a higher risk of preterm birth, miscarriage, cesarean delivery and placenta previa. The study also showed that endometriosis was associated with birth of infants who were small for their gestational age. There was no association, however, between endometriosis and gestational hypertension or preeclampsia.
"Prior studies looking at this issue have reported conflicting results," says Berghella. "Studies like ours help clarify the findings by pooling the data from many studies to give the field a more conclusive answer to a debated research question. The collective data is stronger than any single study alone and often helps shape opinion in the field."
Thomas Jefferson University
Related Preterm Birth Articles:
In a study of predominantly African-American women -- who have a much higher rate of delivering babies early compared with other racial groups -- researchers at Washington University School of Medicine in St.
Babies born preterm run a higher risk of heart failure during childhood and adolescence than those born at full term, researchers at Karolinska Institutet in Sweden report.
The use of two measures, fetal fibronectin (a protein) levels and transvaginal cervical length, had low predictive accuracy for spontaneous preterm birth among women who have not given birth before, according to a study appearing in the March 14 issue of JAMA.
Scientists identified a molecular driver of inflammation that may finally answer a key question about what causes mild systemic prenatal infections to trigger preterm birth.
Treatment with vaginal progesterone reduced the risk of preterm birth, neonatal complications and death in pregnant women with twins and who have a short cervix -- a risk factor for preterm birth -- according to a meta-analysis of individual patient data by researchers at the National Institutes of Health, the Wayne State University School of Medicine, the Detroit Medical Center, and other institutions in the United States and abroad.
Pregnant women increase their chances of vitamin B12 deficiency if they don't consume enough meat, milk or eggs.
A study published on Sept. 1 in PLOS Pathogens reports that GBS produces membrane-bound vesicles containing bacterial factors that can attack the host tissue.
A significant portion of preterm births might be avoided by reducing or eliminating three major risk factors: abnormalities in the interval between pregnancies, the mother's body mass index prior to pregnancy, and the amount of weight gain in pregnancy.
In a study of almost 700 pregnant women who received a cervical stitch designed to prevent preterm labor, the use of one type of suture over another was associated with three times higher risk of stillbirth and almost twice the risk of preterm birth.
Metformin, a medication routinely used by millions of people with type 2 diabetes, may also play an unexpected role in blocking a significant cause of preterm birth.
Related Preterm Birth Reading:
Preterm Birth: Prevention and Management
by Vincenzo Berghella (Editor)
Preterm birth is an increasing challenge in the developed and developing world.
As we begin to understand what contributes to the likelihood of preterm birth, obstetricians and gynecologists can advise mothers and aspiring mothers on how to minimize the risks. Doctors can also monitor those patients who are likely to be at risk to increase the chances of preventing or effectively managing preterm labor.
This practical book provides a clinically focused approach to the prevention and management of premature births, using the best available evidence to provide clear guidance to... View Details
Preterm Birth: Causes, Consequences, and Prevention
by Institute of Medicine (Author), Board on Health Sciences Policy (Author), Committee on Understanding Premature Birth and Assuring Healthy Outcomes (Author), Adrienne Stith Butler (Editor), Richard E. Behrman (Editor)
The increasing prevalence of preterm birth in the United States is a complex public health problem that requires multifaceted solutions. Preterm birth is a cluster of problems with a set of overlapping factors of influence. Its causes may include individual-level behavioral and psychosocial factors, sociodemographic and neighborhood characteristics, environmental exposure, medical conditions, infertility treatments, and biological factors. Many of these factors co-occur, particularly in those who are socioeconomically disadvantaged or who are members of racial and ethnic minority... View Details
Preterm Birth in the United States: A Sociocultural Approach
by Janet M. Bronstein (Author)
This first-of-its-kind volume addresses the myriad of issues relating to―and reviews the plethora of responses to--premature births in the United States, both in national context and compared with other countries. In addition to current clinical data, it examines how preterm births in the U.S. fit in with larger social concerns regarding poverty, racial disparities, reproductive rights, gender expectations, and the business of health care. Comparisons with preterm birth phenomena in Canada, the U.K., and other Western European countries illustrate cultural narratives about motherhood,... View Details
Congenital Abnormalities and Preterm Birth Related to Maternal Illnesses During Pregnancy
by Nándor Ács (Editor), Ferenc G. Bánhidy (Editor), Andrew E. Czeizel (Editor)
The major objective of our studies in the last decade was a systematic analysis of maternal diseases during pregnancy to reveal their possible adverse effects on birth outcomes. The two most important factors of infant mortality were parti- larly analyzed: structural birth defects, known as congenital abnormalities (CAs) and preterm birth (PB). In general the objectives of scienti c studies might be either to test a new hypothesis or to con rm or confront previously published results. However, less frequently the authors/scientists have personal motivations determined by their professional... View Details
Expecting 411: The Insider's Guide to Pregnancy and Childbirth
by Michele Hakakha (Author), Ari Brown (Author)
Congratulations! You’re pregnant! Now, where do you turn to for the best advice? What if you could bottle the wisdom of all those women who came before you—and combine it with the solid medical advice from a renowned Beverly Hills’ OB/GYN and nationally known pediatrician? Expecting 411 is the answer: smart, up-to-date and refreshingly free of paranoia, this is the book you’ll turn to for quick answers to your most pressing questions. Inside, you'll find:Is this normal? From morning sickness to stretch marks, you’ll learn what’s expected—and what’s... View Details
Your Pregnancy and Childbirth: Month to Month, Sixth Edition
by American College of Obstetricians and Gynecologists (Author)
Based on ACOG guidelines and written by the experts in women's health care, this new edition of Your Pregnancy and Childbirth: Month to Month gives your patients the most accurate information available about pregnancy, childbirth, labor and delivery, breastfeeding, and the postpartum period. Key features include the following: Practical, straightforward advice about diet, exercise, prenatal visits and tests, and handling the discomforts of pregnancy Evidence-based guidance in making important decisions about issues such as pain management during labor, VBAC, and circumcision Separate sections... View Details
Oxorn Foote Human Labor and Birth, Sixth Edition
by Glenn David Posner (Author), Amanda Y. Black (Author), Griffith David Jones (Author), Jessica Dy (Author)
THE CLASSIC CHILDBIRTH HANDBOOK--COMPLETELY REVISED AND UPDATED IN FULL COLOR
A Doody's Core Title for 2017!
Edition after acclaimed edition, Oxorn-Foote Human Labor & Birth has provided the most comprehensive, yet accessible overview of obstetrics available. Going beyond scientific theory and a technological orientation, this landmark guide is written for the real world of clinical practice, as it expertly examines all mechanisms of human labor and delivery.
The book begins with a valuable review of clinical anatomy, then thoroughly examines the three... View Details
Our NICU Journey: A NICU Journal for tracking Daily NICU Activities for your baby in the Neonatal Intensive Care Unit
by Trish Ringley (Author)
A brand new journal for tracking your baby's daily activities and statistics in the NICU, from Every Tiny Thing (the NICU specialty brand)
This high-quality baby book is the perfect place to track everything going on in your baby's daily life while in the NICU, including places to track:
・Bonding Activities for the day
・Nurses, Doctors & Caregivers for the day
・Vital signs, labs, meds, procedures, equipment settings
・Highs & Lows
・Notes & Questions to Ask... View Details
Developmental and Therapeutic Interventions in the NICU
by Elsie Vergara "Sc.D. OTR FAO" (Author), Rosemarie Bigsby "Sc.D. OTR FAO" (Author)
The most comprehensive book available on neonatal intervention, this in-depth resource gives professionals the strong foundation of clinical knowledge they'll need to work with high-risk newborns. With a unique developmental and therapeutic perspective that sets it apart from other texts on the subject, the book is filled with research findings and practical guidelines clinicians will use to promote the well-being of infants in the NICU and to involve and support their families. In-service and preservice professionals will benefit froman exploration of different developmental models... View Details
Kangaroo Care: The Best You Can Do to Help Your Preterm Infant
by Susan Ludington-Hoe (Author)
GIVE YOUR PRETERM BABY THE BEST POSSIBLE START IN LIFE
If you have just given birth to a preterm infant, you and your baby both face special challenges. Parents long to help their baby but often feel isolated and frightened by hospital procedures.
Now there is wonderful news for both babies and parents. Kangaroo Care, a technique pioneered in leading neonatal centers worldwide, gives you a unique role: a special way of holding your infant that provides crucial health benefits—including shorter hospital stays.
Based on ground-breaking research,... View Details