Metabolic surgery offers health benefits for patients with high blood pressure

September 15, 2020

Metabolic surgeries, such as gastric bypass and gastric sleeve surgery, are not only effective for treating Type 2 diabetes and obesity. According to a new study led by Erik Stenberg at Örebro University, published September 15 in PLOS Medicine, the surgery also has benefits for people with obesity who have high blood pressure--and can reduce their risk of heart attack, stroke and death.

High blood pressure, particularly when combined with morbid obesity, is a leading cause of death and disability worldwide. Metabolic surgery has been shown to reduce the risk for many conditions that typically accompany obesity, such as type 2 diabetes, high cholesterol and sleep apnea, but it was unclear whether surgery is also effective for treating high blood pressure. To evaluate whether metabolic surgery has benefits for patients with obesity and high blood pressure, the researchers compared two groups of people with these conditions: one that had undergone metabolic surgery, and a control group that hadn't. Individuals in the groups were matched by age, sex and location, and the researchers considered additional factors, such as other health conditions and educational levels. The group that had undergone metabolic surgery had a lower risk of a "major adverse cardiovascular event" such as a stroke, heart attack or cardiac arrest, and they had a lower risk of dying for any reason. Overall, 3.2% of the group that had surgery experienced a major adverse cardiovascular event, compared to 4.5% of the control group.

The new study suggests that metabolic surgery is effective at treating hypertension in individuals with a BMI ?35kg/m 2. Metabolic surgery may not be a global solution to the obesity epidemic, but with these related conditions causing so much death and disease worldwide, surgery should be considered as an effective option for treating patients with obesity and high blood pressure.
-end-
Citation: Stenberg E, Cao Y, Marsk R, Sundbom M, Jernberg T, Näslund E (2020) Association between metabolic surgery and cardiovascular outcome in patients with hypertension: A nationwide matched cohort study. PLoS Med 17(9): e1003307. https://doi.org/10.1371/journal.pmed.1003307

Funding: ES received grants from Region Örebro County (Grant number: OLL-884791) and the Bengt Ihre Foundation. EN received grants from Stockholm County Council, SRP Diabetes, and the NovoNordisk Foundation. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Competing Interests: The authors have declared that no competing interests exist.

In your coverage please use this URL to provide access to the freely available paper: http://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1003307

PLOS

Related Diabetes Articles from Brightsurf:

New diabetes medication reduced heart event risk in those with diabetes and kidney disease
Sotagliflozin - a type of medication known as an SGLT2 inhibitor primarily prescribed for Type 2 diabetes - reduces the risk of adverse cardiovascular events for patients with diabetes and kidney disease.

Diabetes drug boosts survival in patients with type 2 diabetes and COVID-19 pneumonia
Sitagliptin, a drug to lower blood sugar in type 2 diabetes, also improves survival in diabetic patients hospitalized with COVID-19, suggests a multicenter observational study in Italy.

Making sense of diabetes
Throughout her 38-year nursing career, Laurel Despins has progressed from a bedside nurse to a clinical nurse specialist and has worked in medical, surgical and cardiac intensive care units.

Helping teens with type 1 diabetes improve diabetes control with MyDiaText
Adolescence is a difficult period of development, made more complex for those with Type 1 diabetes mellitus (T1DM).

Diabetes-in-a-dish model uncovers new insights into the cause of type 2 diabetes
Researchers have developed a novel 'disease-in-a-dish' model to study the basic molecular factors that lead to the development of type 2 diabetes, uncovering the potential existence of major signaling defects both inside and outside of the classical insulin signaling cascade, and providing new perspectives on the mechanisms behind insulin resistance in type 2 diabetes and possibly opportunities for the development of novel therapeutics for the disease.

Tele-diabetes to manage new-onset diabetes during COVID-19 pandemic
Two new case studies highlight the use of tele-diabetes to manage new-onset type 1 diabetes in an adult and an infant during the COVID-19 pandemic.

Genetic profile may predict type 2 diabetes risk among women with gestational diabetes
Women who go on to develop type 2 diabetes after having gestational, or pregnancy-related, diabetes are more likely to have particular genetic profiles, suggests an analysis by researchers at the National Institutes of Health and other institutions.

Maternal gestational diabetes linked to diabetes in children
Children and youth of mothers who had gestational diabetes during pregnancy are at increased risk of diabetes themselves, according to new research published in CMAJ (Canadian Medical Association Journal).

Two diabetes medications don't slow progression of type 2 diabetes in youth
In youth with impaired glucose tolerance or recent-onset type 2 diabetes, neither initial treatment with long-acting insulin followed by the drug metformin, nor metformin alone preserved the body's ability to make insulin, according to results published online June 25 in Diabetes Care.

People with diabetes visit the dentist less frequently despite link between diabetes, oral health
Adults with diabetes are less likely to visit the dentist than people with prediabetes or without diabetes, finds a new study led by researchers at NYU Rory Meyers College of Nursing and East Carolina University's Brody School of Medicine.

Read More: Diabetes News and Diabetes Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.