Top jaundice experts present latest treatment information during live Web cast from Pittsburgh

September 19, 2006

Early detection and prompt treatment of neonatal jaundice, also known as hyperbilirubinemia, can prevent this common newborn disorder from posing a threat of brain damage.

Neonatal jaundice is a yellowing of the skin and eyes caused by elevated bilirubin levels in the blood. It affects 60 percent of full-term infants and 80 percent of preterm infants in the first several days after birth. Extremely high levels can lead to bilirubin-induced brain damage, a condition known as kernicterus.

Two of the world's leading experts on this condition will present the latest information on the causes, treatment, outcomes and prevention of severe neonatal hyperbilirubnemia during a continuing medical education event at 8 a.m. Thursday, Sept. 21, 2006, at Children's Hospital of Pittsburgh. The event also will be available via live Web cast on Children's Web site,

This will include a presentation by Jon F. Watchko, MD, a neonatologist in the Division of Newborn Medicine at Children's and Magee-Womens Hospital, and M. Jeffrey Maisels, MBBCh, Chair of the Department of Pediatrics at William Beaumont Hospital, Royal Oak, Mich.

Following their presentation, there will be a panel discussion moderated by Gary A. Silverman, MD, PhD, Chief of the Divison of Newborn Medicine at Children's and Magee-Womens Hospital. Also participating in the panel discussion will be John LaBella, MD, a pediatrician with Children's Community Pediatrics - Bass Wolfson. The panel will take questions from the live audience as well as the Web audience.

Dr. Watchko also is Professor of Pediatrics, Obstetrics, Gynecology and Reproductive Sciences at the University of Pittsburgh School of Medicine. His research into hyperbilirubinemic encephalopathy is focused on the role P-glycoprotein plays in limiting bilirubin passage across the blood-brain barrier.

Dr. Maisels served as Chair of the American Academy of Pediatrics Sub-Committee on Neonatal Hyperbilirubinemia and was responsible for drafting the 2004 AAP guidelines on management of hyperbilirubinemia in the newborn. His publications on this topic extend over 30 years. He is the author or coauthor of more than 190 research publications and chapters in books, most of which deal with the subject of bilirubin metabolism and jaundice in the newborn infant.
Editor's Note: Registration for the live Web cast, and the post-event archived session, is available through Children's at

Children's Hospital of Pittsburgh

Related Jaundice Articles from Brightsurf:

Maternal insecticide use during pregnancy and neonatal jaundice
Association between pesticide usage during pregnancy and neonatal hyperbilirubinemia requiring treatment: The Japan Environment and Children's study.

Immune protein IL-17A responsible for lethal side effects of gastric cancer
The formation of scar tissue, or fibrosis, as gastric cancer disseminates throughout the peritoneum can be more lethal than the cancer itself and can interfere with chemotherapy.

App detecting jaundice may prevent deaths in newborns
A smartphone app that allows users to check for jaundice in newborn babies simply by taking a picture of the eye may be an effective, low-cost way to screen for the condition, according to a pilot study led by UCL and UCLH.

A single dose of yellow fever vaccine does not offer lasting protection to all children
José Enrique Mejía, Inserm researcher at Unit 1043 Center for Pathophysiology of Toulouse Purpan and Cristina Domingo from the Robert Koch Institute in Berlin have recently shown that around half of children initially protected by the yellow fever vaccination at 9 months of age lose that protection within the next 2 to 5 years, due to disappearance of the neutralizing antibodies.

More than just jaundice: Mouse study shows bilirubin may protect the brain
In studies in mice, Johns Hopkins Medicine researchers report they have found that bilirubin, a bile pigment most commonly known for yellowing the skin of people with jaundice, may play an unexpected role in protecting brain cells from damage from oxidative stress.

Liver transplants could be redundant with discovery of new liver cell
Researchers at King's College London have used single cell RNA sequencing to identify a type of cell that may be able to regenerate liver tissue, treating liver failure without the need for transplants.

Scientists discover how hepatitis C 'ghosts' our immune system
Scientists from Trinity College Dublin have discovered how the highly infectious and sometimes deadly hepatitis C virus (HCV) 'ghosts' our immune system and remains undiagnosed in many people.

Behold the Bili-ruler: A novel, low-cost device for screening neonatal hyperbilirubinemia
A team from Brigham and Women's Hospital recently reported the creation and validation of a novel tool, the Bili-ruler, designed for use by frontline health workers to screen for hyperbilirubinemia in low-resource settings.

New insights on liver injury in men taking body building supplements
In a study reported in Alimentary Pharmacology & Therapeutics, 44 men with liver injury, attributed to over-the-counter bodybuilding supplements, experienced a uniform and distinctive pattern of signs and symptoms that were often prolonged, difficult to treat, and accompanied by disability and weight loss.

Wireless, battery-free sensors monitor skin exposure to solar radiation
Researchers have created wireless, battery-free sensors that can monitor exposure to solar radiation in real time.

Read More: Jaundice News and Jaundice Current Events is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to