Festschrift dedicated to Mathilde Krim includes scientific research by Krim fellows

September 20, 2018

New Rochelle, NY, September 20, 2018--A special Festschrift dedicated to the memory of Dr. Mathilde Krim celebrates her life and medical and scientific career, including her leadership role as the Founder of the American Foundation of AIDS Research (amfAR). Articles highlighting her life and legacy and a wide range of scientific articles contributed by the Krim Fellows are included in this issue of AIDS Research and Human Retroviruses, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. Click here to read the issue free on the AIDS Research and Human Retroviruses website.

In the article entitled "CD4-HIV-1 Envelope Interactions: Critical Insights for the Simian/HIV/Macaque Model," coauthored by Amit Sharma, Fred Hutchinson Cancer Research Center (Seattle, WA) and The Ohio State University (Columbus) and Julie Overbaugh, Fred Hutchinson Cancer Research Center, the researchers demonstrate the importance of macaque models of simian HIV and infection with simian/HIV-1 viruses in the design of effective vaccines. Simian/HIV-1 viruses encode the HIV-1 envelope protein (env), which is an essential target in the CD4-HIV-1 interaction, virus entry, and the production of HIV-1-neutralizing antibodies.

Ester Lopez and Amy Chung, The University of Melbourne (Parkville, Australia), Robin Shattock, Imperial College London (U.K.), and Stephen Kent, The University of Melbourne and Monash University (Melbourne), present "The Multifaceted Nature of Immunoglobulin A and Its Complex Role in HIV," in which they examine the dichotomy of published studies that show IgA to be either protective or harmful to the host with HIV. For example, with mucosal IgA evidence suggests a protective role, whereas IgA in serum seems to correlate with disease progression.

"Fuzzy Modeling of the Enactment of Stigma by Healthcare Personnel Toward People Living with HIV in the Frame of Counterfactual Thinking: A Mixed-Method Approach," was coauthored by Zahra Alipour Darvishi, Islamic Azad University (Tehran, Iran), Fardad Doroudi, UNAIDS (Tehran), and Navid Madani, Dana-Farber Cancer Center (Boston, MA) and Harvard Medical School (Boston). The researchers' goal was to study the formation of stigma against people living with HIV based on the attitudes of healthcare providers. They identified six patterns of healthcare providers' judgments. They believe that their methodology, based on a more in-depth understanding of healthcare providers' judgments can provide more accurate predictions about healthcare providers' discriminatory behavior.

"This Festschrift is dedicated to the memory of Dr. Mathilde Krim, Scientist, Pioneer, and Founder of the American Foundation of AIDS Research (amfAR), whose legacy is perpetuated through the Krim Fellows Program that supports outstanding young HIV/AIDS researchers as they transition from advanced training to starting their own independent research programs," says Thomas Hope, PhD, Editor-in-Chief of AIDS Research and Human Retroviruses and Professor of Cell and Molecular Biology at Northwestern University, Feinberg School of Medicine (Chicago, IL).
About the Journal

AIDS Research and Human Retroviruses, published monthly online with open access options and in print, presents papers, reviews, and case studies documenting the latest developments and research advances in the molecular biology of HIV and SIV and innovative approaches to HIV vaccine and therapeutic drug research, including the development of antiretroviral agents and immune-restorative therapies. Content also explores the molecular and cellular basis of HIV pathogenesis and HIV/HTLV epidemiology. The Journal features rapid publication of emerging sequence information, reports on clinical trials of emerging HIV therapies, and images in HIV research. Tables of content and a sample issue may be viewed on the AIDS Research and Human Retroviruses website.

About the Publisher

Mary Ann Liebert, Inc., publishers is a privately held, fully integrated media company known for establishing authoritative peer-reviewed journals in many promising areas of science and biomedical research, including AIDS Patient Care and STDs, Viral Immunology, and Journal of Interferon and Cytokine Research. Its biotechnology trade magazine, GEN (Genetic Engineering & Biotechnology News), was the first in its field and is today the industry's most widely read publication worldwide. A complete list of the firm's 80 journals, books, and newsmagazines is available on the Mary Ann Liebert, Inc., publishers website.

Mary Ann Liebert, Inc./Genetic Engineering News

Related HIV Articles from Brightsurf:

BEAT-HIV Delaney collaboratory issues recommendations measuring persistent HIV reservoirs
Spearheaded by Wistar scientists, top worldwide HIV researchers from the BEAT-HIV Martin Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy (BEAT-HIV Collaboratory) compiled the first comprehensive set of recommendations on how to best measure the size of persistent HIV reservoirs during cure-directed clinical studies.

The Lancet HIV: Study suggests a second patient has been cured of HIV
A study of the second HIV patient to undergo successful stem cell transplantation from donors with a HIV-resistant gene, finds that there was no active viral infection in the patient's blood 30 months after they stopped anti-retroviral therapy, according to a case report published in The Lancet HIV journal and presented at CROI (Conference on Retroviruses and Opportunistic Infections).

Children with HIV score below HIV-negative peers in cognitive, motor function tests
Children who acquired HIV in utero or during birth or breastfeeding did not perform as well as their peers who do not have HIV on tests measuring cognitive ability, motor function and attention, according to a report published online today in Clinical Infectious Diseases.

Efforts to end the HIV epidemic must not ignore people already living with HIV
Efforts to prevent new HIV transmissions in the US must be accompanied by addressing HIV-associated comorbidities to improve the health of people already living with HIV, NIH experts assert in the third of a series of JAMA commentaries.

The Lancet HIV: Severe anti-LGBT legislations associated with lower testing and awareness of HIV in African countries
This first systematic review to investigate HIV testing, treatment and viral suppression in men who have sex with men in Africa finds that among the most recent studies (conducted after 2011) only half of men have been tested for HIV in the past 12 months.

The Lancet HIV: Tenfold increase in number of adolescents on HIV treatment in South Africa since 2010, but many still untreated
A new study of more than 700,000 one to 19-year olds being treated for HIV infection suggests a ten-fold increase in the number of adolescents aged 15 to 19 receiving HIV treatment in South Africa, according to results published in The Lancet HIV journal.

Starting HIV treatment in ERs may be key to ending HIV spread worldwide
In a follow-up study conducted in South Africa, Johns Hopkins Medicine researchers say they have evidence that hospital emergency departments (EDs) worldwide may be key strategic settings for curbing the spread of HIV infections in hard-to-reach populations if the EDs jump-start treatment and case management as well as diagnosis of the disease.

NIH HIV experts prioritize research to achieve sustained ART-free HIV remission
Achieving sustained remission of HIV without life-long antiretroviral therapy (ART) is a top HIV research priority, according to a new commentary in JAMA by experts at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.

The Lancet HIV: PrEP implementation is associated with a rapid decline in new HIV infections
Study from Australia is the first to evaluate a population-level roll-out of pre-exposure prophylaxis (PrEP) in men who have sex with men.

Researchers date 'hibernating' HIV strains, advancing BC's leadership in HIV cure research
Researchers have developed a novel way for dating 'hibernating' HIV strains, in an advancement for HIV cure research.

Read More: HIV News and HIV Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.