Nav: Home

Anxious and forgetful after menopause? Low estrogen may be to blame

October 01, 2018

Knoxville, Tenn. (October 1, 2018)--Lack of estrogen may play a role in the development of anxiety and memory problems, according to a new rodent study. The findings will be presented today at the American Physiological Society's (APS) Cardiovascular, Renal and Metabolic Diseases: Sex-Specific Implications for Physiology conference in Knoxville, Tenn.

Estrogen, the primary female sex hormone, regulates the female reproductive system. As a woman approaches menopause, dwindling ovarian function--which results in low levels of ovarian hormones-- causes the estrogen supply in the brain to drop. Areas of the brain that are involved in mood, behavior and cognition have a high concentration of proteins that bind to estrogen (estrogen receptors). Researchers from Georgetown University in Washington, D.C., and the Federal University of Ouro Preto in Brazil theorized that for this reason, "estrogen deficiency could lead to anxiety development and memory impairments."

The research team studied female rats without ovaries to mimic human menopause. They administered standardized tests that measured anxiety and assessed short-term recognition of objects and spatial memory (memory of temporary locations and the relationships between objects in space). The menopausal rats showed higher levels of anxiety and a decrease in recognition memory compared to an age-matched control group. There was no difference in spatial memory between the two groups. These results suggest that normal hormone imbalances contribute to some of the emotional symptoms associated with menopause, such as anxiety, as well as minor memory problems.
-end-
The study, "Ovariectomy induces anxiety-like behavior and short-term recognition memory impairment," will be part of a poster session on Monday, October 1, at the Crowne Plaza Knoxville.

NOTE TO JOURNALISTS: The Cardiovascular, Renal and Metabolic Diseases: Sex-Specific Implications for Physiology conference will be held September 30-October 3 in Knoxville, Tenn. To schedule an interview with the conference organizers or presenters, contact the the communications@the-aps.org>APS Communications Office or 301-634-7209. Find more research highlights in the APS Press Room.

Physiology is the study of how molecules, cells, tissues and organs function in health and disease. Established in 1887, the American Physiological Society (APS) was the first U.S. society in the biomedical sciences field. The Society represents more than 10,000 members and publishes 15 peer-reviewed journals with a worldwide readership.

American Physiological Society

Related Memory Articles:

Memory boost with just one look
HRL Laboratories, LLC, researchers have published results showing that targeted transcranial electrical stimulation during slow-wave sleep can improve metamemories of specific episodes by 20% after only one viewing of the episode, compared to controls.
VR is not suited to visual memory?!
Toyohashi university of technology researcher and a research team at Tokyo Denki University have found that virtual reality (VR) may interfere with visual memory.
The genetic signature of memory
Despite their importance in memory, the human cortex and subcortex display a distinct collection of 'gene signatures.' The work recently published in eNeuro increases our understanding of how the brain creates memories and identifies potential genes for further investigation.
How long does memory last? For shape memory alloys, the longer the better
Scientists captured live action details of the phase transitions of shape memory alloys, giving them a better idea how to improve their properties for applications.
A NEAT discovery about memory
UAB researchers say over expression of NEAT1, an noncoding RNA, appears to diminish the ability of older brains to form memories.
Molecular memory can be used to increase the memory capacity of hard disks
Researchers at the University of Jyväskylä have taken part in an international British-Finnish-Chinese collaboration where the first molecule capable of remembering the direction of a magnetic above liquid nitrogen temperatures has been prepared and characterized.
Memory transferred between snails
Memories can be transferred between organisms by extracting ribonucleic acid (RNA) from a trained animal and injecting it into an untrained animal, as demonstrated in a study of sea snails published in eNeuro.
An immunological memory in the brain
Inflammatory reactions can change the brain's immune cells in the long term -- meaning that these cells have an 'immunological memory.' This memory may influence the progression of neurological disorders that occur later in life, and is therefore a previously unknown factor that could influence the severity of these diseases.
Anxiety can help your memory
Anxiety can help people to remember things, a study from the University of Waterloo has found.
Pores with a memory
Whether for separation processes, photovoltaics, catalysis, or electronics, porous polymer membranes are needed in many fields.
More Memory News and Memory Current Events

Trending Science News

Current Coronavirus (COVID-19) News

Top Science Podcasts

We have hand picked the top science podcasts of 2020.
Now Playing: TED Radio Hour

Climate Mindset
In the past few months, human beings have come together to fight a global threat. This hour, TED speakers explore how our response can be the catalyst to fight another global crisis: climate change. Guests include political strategist Tom Rivett-Carnac, diplomat Christiana Figueres, climate justice activist Xiye Bastida, and writer, illustrator, and artist Oliver Jeffers.
Now Playing: Science for the People

#562 Superbug to Bedside
By now we're all good and scared about antibiotic resistance, one of the many things coming to get us all. But there's good news, sort of. News antibiotics are coming out! How do they get tested? What does that kind of a trial look like and how does it happen? Host Bethany Brookeshire talks with Matt McCarthy, author of "Superbugs: The Race to Stop an Epidemic", about the ins and outs of testing a new antibiotic in the hospital.
Now Playing: Radiolab

Speedy Beet
There are few musical moments more well-worn than the first four notes of Beethoven's Fifth Symphony. But in this short, we find out that Beethoven might have made a last-ditch effort to keep his music from ever feeling familiar, to keep pushing his listeners to a kind of psychological limit. Big thanks to our Brooklyn Philharmonic musicians: Deborah Buck and Suzy Perelman on violin, Arash Amini on cello, and Ah Ling Neu on viola. And check out The First Four Notes, Matthew Guerrieri's book on Beethoven's Fifth. Support Radiolab today at Radiolab.org/donate.