Nav: Home

Cerebral reperfusion of reading network predicts recovery of reading ability after stroke

October 01, 2019

East Hanover, NJ. October 1, 2019. A team of New Jersey stroke researchers has linked recovery of reading and language competence with cerebral blood flow in the left reading network. Their findings may contribute to new approaches to identifying and treating reading deficits after stroke. The open access article, "Cerebral perfusion of the left reading network predicts recovery of reading in subacute to chronic stroke" (doi: https://doi.org/10.1002/hbm.24773) was epublished on August 26, 2019 in Human Brain Mapping. The authors are Olga Boukrina, PhD, and A.M. Barrett, MD, of Kessler Foundation, and William Graves, PhD, of Rutgers, the State University of New Jersey.

Despite the fundamental role of reading ability in everyday living, little research has been conducted on patterns of reading recovery after stroke, or the development of interventions to improve reading outcomes. In this study of left-brain stroke, a team of New Jersey scientists examined patterns of cerebral perfusion bilaterally, including left and right networks of brain areas important for healthy reading, the area surrounding the stroke lesion, and the corresponding contralateral area.

They enrolled 31 participants during inpatient rehabilitation, within 5 weeks of left-sided stroke. All underwent functional magnetic resonance imaging, psychometric testing, neurological examination and tests for phonological, orthographic and semantic impairments. Fifteen participants had follow-up studies at 3 months post stroke. Analysis of data from the subacute and chronic phases showed that recovery of reading and language competence correlated with increases in cerebral blood flow in the left reading network.

"Our findings support the utility of cerebral perfusion as a biomarker for recovery after stroke," said Dr. Boukrina, research scientist at the Center for Stroke Rehabilitation Research at Kessler Foundation, "and indicate that early reperfusion of the left reading network is essential to reading performance. We also found that increased perfusion of the right reading network correlated with worse reading performance, which challenges the belief that this increased activity is a necessary transition in the recovery process."

The team plans future studies of larger populations, with inclusion of additional time points in order to better define the trajectory of recovery after stroke. "Reading deficits hinder the ability to participate fully in rehabilitation, to return to work, and function effectively at home and in the community," Dr. Boukrina remarked. "Pursuing this avenue of research will help us discover ways to restore function and improve outcomes for individuals recovering from left-brain stroke."
-end-
This study was supported by grants from the National Institute for Child Health & Human Development (R00-HD065839 and R21-HD095488), and the Mabel H. Flory Foundation.

Learn about ongoing stroke research at Kessler Foundation at: https://kesslerfoundation.org/research/studies/stroke

Interested in more information? Email our recruitment specialist at ResearchStudies@KesslerFoundation.org

About Kessler Foundation

Kessler Foundation, a major nonprofit organization in the field of disability, is a global leader in rehabilitation research that seeks to improve cognition, mobility, and long-term outcomes--including employment--for people with neurological disabilities caused by diseases and injuries of the brain and spinal cord. Kessler Foundation leads the nation in funding innovative programs that expand employment opportunities for people with disabilities.

For more information, visit KesslerFoundation.org.

Facebook |http://www.facebook.com/KesslerFoundation
Twitter | http://twitter.com/KesslerFdn
Instagram | https://www.instagram.com/kesslerfdn
YouTube | http://www.youtube.com/user/KesslerFoundation
iTunes & SoundCloud | http://www.soundcloud.com/kesslerfoundation

Contacts:

Carolann Murphy, PA
Senior Staff Writer
973.324.8382
CMurphy@KesslerFoundation.org

Rob Gerth
Director, Communications
973.323.3675
Rgerth@KesslerFoundation.org

Kessler Foundation

Related Stroke Articles:

'Time is vision' after a stroke
University of Rochester researchers studied stroke patients who experienced vision loss and found that the patients retained some visual abilities immediately after the stroke but these abilities diminished gradually and eventually disappeared permanently after approximately six months.
More stroke awareness, better eating habits may help reduce stroke risk for young adult African-Americans
Young African-Americans are experiencing higher rates of stroke because of health conditions such as high blood pressure, diabetes and obesity, yet their perception of their stroke risk is low.
How to help patients recover after a stroke
The existing approach to brain stimulation for rehabilitation after a stroke does not take into account the diversity of lesions and the individual characteristics of patients' brains.
Kids with headache after stroke might be at risk for another stroke
A new study has found a high incidence of headaches in pediatric stroke survivors and identified a possible association between post-stroke headache and stroke recurrence.
High stroke impact in low- and middle-income countries examined at 11th World Stroke Congress
Less wealthy countries struggle to meet greater need with far fewer resources.
Marijuana use might lead to higher risk of stroke, World Stroke Congress to be told
A five-year study of hospital statistics from the United States shows that the incidence of stroke has risen steadily among marijuana users even though the overall rate of stroke remained constant over the same period.
We need to talk about sexuality after stroke
Stroke survivors and their partners are not adequately supported to deal with changes to their relationships, self-identity, gender roles and intimacy following stroke, according to new research from the University of Sydney.
Standardized stroke protocol can ensure ELVO stroke patients are treated within 60 minutes
A new study shows that developing a standardized stroke protocol of having neurointerventional teams meet suspected emergent large vessel occlusion (ELVO) stroke patients upon their arrival at the hospital achieves a median door-to-recanalization time of less than 60 minutes.
Stroke affects more than just the physical
A new study looks at what problems affect people most after a stroke and it provides a broader picture than what some may usually expect to see.
Stroke journal features women's studies on how gender influences stroke risk, treatment and outcomes
Many aspects of strokes affect women and men differently, and four articles in the American Heart Association's journal Stroke highlight recent research and identify future research needs.
More Stroke News and Stroke Current Events

Trending Science News

Current Coronavirus (COVID-19) News

Top Science Podcasts

We have hand picked the top science podcasts of 2020.
Now Playing: TED Radio Hour

Listen Again: IRL Online
Original broadcast date: March 20, 2020. Our online lives are now entirely interwoven with our real lives. But the laws that govern real life don't apply online. This hour, TED speakers explore rules to navigate this vast virtual space.
Now Playing: Science for the People

#573 Penis. That's It. That's the title.
This episode is about penises. That was your content warning. Penises. Where they came from. Why they're useful. And the many, many wild things that animals do with them. Come for the world's oldest penis, stay for the creature that ejaculates 80 percent of its bodyweight. Host Bethany Brookshire talks with Emily Willingham about her new book, "Phallacy: Life Lessons from the Animal Penis".
Now Playing: Radiolab

Falling
There are so many ways to fall–in love, asleep, even flat on your face. This hour, Radiolab dives into stories of great falls.  We jump into a black hole, take a trip over Niagara Falls, upend some myths about falling cats, and plunge into our favorite songs about falling. Support Radiolab by becoming a member today at Radiolab.org/donate.