Nav: Home

Clinical trial tests spinal manipulation therapy for migraines

October 03, 2016

Manual-therapy randomized controlled trials (RCTs) are difficult to perform because it's challenging to conceal a placebo when patients are able to physically feel a treatment that's being delivered. Now, though, researchers have successfully completed the first manual-therapy RCT with a documented successful blinding. The three-armed trial evaluated the efficacy of chiropractic spinal manipulative therapy (CSMT) in the treatment of migraine versus placebo (sham chiropractic) and control (usual drug treatment).

Migraine days were significantly reduced within all three groups from baseline to post-treatment; the effect continued in the CSMT and placebo groups at all follow-up time points, whereas the control group returned to baseline. The effect of CSMT was likely due to a placebo response.

The findings are published in the European Journal of Neurology.
-end-


Wiley

Related Placebo Articles:

The placebo effect can mend a broken heart too, CU Boulder study shows
Feeling heartbroken from a recent breakup? Just believing you're doing something to help yourself get over your ex can influence brain regions associated with emotional regulation and lessen the perception of pain.
Successful insomnia treatment may require nothing more than a placebo
A new study published in Brain indicates that successful treatment for insomnia may not actually require complicated neurofeedback (direct training of brain functions).
Placebo and valium are equally effective for acute lower back pain in the ER
Emergency patients treated with naproxen and placebo had outcomes as good as or better than patients treated with naproxen and diazepam (trade name Valium) for acute lower back pain, according to the results of a double-blind, randomized clinical trial published last week in Annals of Emergency Medicine ('Diazepam Is No Better Than Placebo When Added to Naproxen for Acute Low Back Pain').
Evaluation of recombinant antithrombin vs. placebo in preterm preeclampsia
Researchers with the PRESERVE-1 Study Group University of Texas Health Science Center at Houston -- McGovern Medical School, Houston, Texas, and Yale School of Medicine, New Haven, Conn., present findings of a study titled Randomized double-blind placebo controlled evaluation of the safety and efficacy of recombinant Antithrombin versus placebo in preterm preeclampsia.
Exploiting the placebo effect can improve recovery of heart surgery patients
Exploiting the placebo effect significantly improved the recovery of patients undergoing heart surgery according to new research published in the open access journal BMC Medicine.
Placebo sweet spot for pain relief found in brain
Scientists have identified for the first time the region in the brain responsible for the placebo effect in pain relief.
Placebo reduces back pain -- even when patients know they're taking placebo
For patients with chronic back pain, 'open' treatment with placebo -- informing patients that they are taking an inactive pill, and why it might be helpful -- leads to reductions in pain and disability, reports a study in PAIN®, the official publication of the International Association for the Study of Pain.
Study finds knowingly taking placebo pills eases pain
This is the first study to demonstrate beneficial placebo effect for lower back pain sufferers who knew they were taking 'fake pills.' Patients who knowingly took placebos reported 30 percent less pain and 29 percent reduction in disability compared to control group.
Clinical trial tests spinal manipulation therapy for migraines
Manual-therapy randomized controlled trials (RCTs) are difficult to perform because it's challenging to conceal a placebo when patients are able to physically feel a treatment that's being delivered.
Anti-interleukin-1 alpha antibody MABp1 improves outcomes significantly over placebo
A novel anti-interleukin 1-alpha antibody has shown a significant impact on symptoms, and a high level of safety and tolerability in patients with advanced colorectal cancer, according to phase III data (1) presented at the European Society for Medical Oncology's 18th World Congress of Gastrointestinal Cancer in Barcelona, Spain.

Related Placebo Reading:

Best Science Podcasts 2019

We have hand picked the best science podcasts for 2019. Sit back and enjoy new science podcasts updated daily from your favorite science news services and scientists.
Now Playing: TED Radio Hour

Bias And Perception
How does bias distort our thinking, our listening, our beliefs... and even our search results? How can we fight it? This hour, TED speakers explore ideas about the unconscious biases that shape us. Guests include writer and broadcaster Yassmin Abdel-Magied, climatologist J. Marshall Shepherd, journalist Andreas Ekström, and experimental psychologist Tony Salvador.
Now Playing: Science for the People

#513 Dinosaur Tails
This week: dinosaurs! We're discussing dinosaur tails, bipedalism, paleontology public outreach, dinosaur MOOCs, and other neat dinosaur related things with Dr. Scott Persons from the University of Alberta, who is also the author of the book "Dinosaurs of the Alberta Badlands".