American Cancer Society awards research grants to 109 investigators at 77 institutions nationwide
October 04, 2007ATLANTA--October 04, 2007 - The American Cancer Society, the largest non-government, not-for-profit funding source of cancer research in the United States, has awarded 109 national research and training grants totaling more than $52.6 million in the first of two grant cycles for 2008. Of the grants, 91 are new and 18 are renewals of previous grants. All of the grants go into effect January 1, 2008.
The American Cancer Society's Research and Training Program has funded 40 Nobel Prize laureates since its inception in 1946, during which time it has invested about $3.1 billion in cancer research, much of that focusing on the work of promising new investigators. The Society currently funds 938 multi-year grants totaling over $457 million. Among the newly awarded grants approved for funding:
- Katherine Crew, MD of Columbia University in New York, N.Y. is examining the role of green tea extracts to possibly lower the risk of ER-negative breast cancer, a form of breast cancer which is often found in younger women and associated with a poorer prognosis.
- Prasad Jallepalli, MD, PhD of Memorial Sloan-Kettering Cancer Center in New York. N.Y. is investigating a new function for the protein, Polo kinase, which is higly overexpressed in many cancers and can "turn on" major cell division pathways at exactly the right time and right place.
- Nomeli Nunez, PhD of the University of Texas, Austin is working on understanding the relationship in post-menopausal women between obesity and an increase in breast cancer.
- Adam Marcus, PhD of Emory University in Atlanta, Ga. is studying how non-small cell lung cancer takes on aggressive metastatic characteristics and how a particular tumor suppressor, named LKB1, plays a role when it triggers the front part of a cell to become indistinguishable from the end.
- Sara Higgins, PhD of Mount Sinai School of Medicine, New York, N.Y. focuses on psychological distress that may impact factors in the blood to increase the risk of blood clot formation in women with ovarian cancer.
- Rebecca Page, PhD of Brown University in Providence, R.I. is investigating the three-dimensional structure of an important protein called hematopoetic protein tyrosine phosphatase (HePTP) which if it malfunctions, can more easily lead to leukemia .
- Christopher Umbricht, MD, PhD of Johns Hopkins University in Baltimore, Md. is identifying molecular patterns of gene expression in cancerous thyroid nodules to be compared to that of noncancerous thyroid nodules.
- William Hawkins, MD of Washington University, St. Louis, Mo. is studying a novel, peptide inhibitor that targets two apoptotic pathways causing programmed cell death.
- David Buckley, MD of Oregon Health and Sciences University in Portland, Ore. is examining the relationship between disability status and receipt of cancer screening and preventive services in community-based primary care settings with specific regard to tobacco use among adults with disabilities living in rural areas.
The Council for Extramural Grants also approved 87 research grant applications that could not be funded due to budgetary constraints. The so-called "pay-if" grants represent work that pass the Society's multi-disciplinary review process, but go beyond the Society's current funding resources.
-end-
The American Cancer Society is dedicated to eliminating cancer as a major health problem by saving lives, diminishing suffering and preventing cancer through research, education, advocacy and service. Founded in 1913 and with national headquarters in Atlanta, the Society has 13 regional Divisions and local offices in 3,400 communities, involving millions of volunteers across the United States. For more information anytime, call toll free 1-800-ACS-2345 or visit www.cancer.org.To read more about the Society's research programs, visit: http://www.cancer.org/research
American Cancer Society
Related Breast Cancer Articles from Brightsurf:
Oncotarget: IGF2 expression in breast cancer tumors and in breast cancer cells
The Oncotarget authors propose that methylation of DVDMR represents a novel epigenetic biomarker that determines the levels of IGF2 protein expression in breast cancer.
Breast cancer: AI predicts which pre-malignant breast lesions will progress to advanced cancer
New research at Case Western Reserve University in Cleveland, Ohio, could help better determine which patients diagnosed with the pre-malignant breast cancer commonly as stage 0 are likely to progress to invasive breast cancer and therefore might benefit from additional therapy over and above surgery alone.
Partial breast irradiation effective treatment option for low-risk breast cancer
Partial breast irradiation produces similar long-term survival rates and risk for recurrence compared with whole breast irradiation for many women with low-risk, early stage breast cancer, according to new clinical data from a national clinical trial involving researchers from The Ohio State University Comprehensive Cancer Center - Arthur G.
Breast screening linked to 60 per cent lower risk of breast cancer death in first 10 years
Women who take part in breast screening have a significantly greater benefit from treatments than those who are not screened, according to a study of more than 50,000 women.
More clues revealed in link between normal breast changes and invasive breast cancer
A research team, led by investigators from Georgetown Lombardi Comprehensive Cancer Center, details how a natural and dramatic process -- changes in mammary glands to accommodate breastfeeding -- uses a molecular process believed to contribute to survival of pre-malignant breast cells.
Breast tissue tumor suppressor PTEN: A potential Achilles heel for breast cancer cells
A highly collaborative team of researchers at the Medical University of South Carolina and Ohio State University report in Nature Communications that they have identified a novel pathway for connective tissue PTEN in breast cancer cell response to radiotherapy.
Computers equal radiologists in assessing breast density and associated breast cancer risk
Automated breast-density evaluation was just as accurate in predicting women's risk of breast cancer, found and not found by mammography, as subjective evaluation done by radiologists, in a study led by researchers at UC San Francisco and Mayo Clinic.
Blood test can effectively rule out breast cancer, regardless of breast density
A new study published in PLOS ONE demonstrates that Videssa® Breast, a multi-protein biomarker blood test for breast cancer, is unaffected by breast density and can reliably rule out breast cancer in women with both dense and non-dense breast tissue.
Study shows influence of surgeons on likelihood of removal of healthy breast after breast cancer dia
Attending surgeons can have a strong influence on whether a patient undergoes contralateral prophylactic mastectomy after a diagnosis of breast cancer, according to a study published by JAMA Surgery.
Young breast cancer patients undergoing breast conserving surgery see improved prognosis
A new analysis indicates that breast cancer prognoses have improved over time in young women treated with breast conserving surgery.
Read More: Breast Cancer News and Breast Cancer Current Events
The Oncotarget authors propose that methylation of DVDMR represents a novel epigenetic biomarker that determines the levels of IGF2 protein expression in breast cancer.
Breast cancer: AI predicts which pre-malignant breast lesions will progress to advanced cancer
New research at Case Western Reserve University in Cleveland, Ohio, could help better determine which patients diagnosed with the pre-malignant breast cancer commonly as stage 0 are likely to progress to invasive breast cancer and therefore might benefit from additional therapy over and above surgery alone.
Partial breast irradiation effective treatment option for low-risk breast cancer
Partial breast irradiation produces similar long-term survival rates and risk for recurrence compared with whole breast irradiation for many women with low-risk, early stage breast cancer, according to new clinical data from a national clinical trial involving researchers from The Ohio State University Comprehensive Cancer Center - Arthur G.
Breast screening linked to 60 per cent lower risk of breast cancer death in first 10 years
Women who take part in breast screening have a significantly greater benefit from treatments than those who are not screened, according to a study of more than 50,000 women.
More clues revealed in link between normal breast changes and invasive breast cancer
A research team, led by investigators from Georgetown Lombardi Comprehensive Cancer Center, details how a natural and dramatic process -- changes in mammary glands to accommodate breastfeeding -- uses a molecular process believed to contribute to survival of pre-malignant breast cells.
Breast tissue tumor suppressor PTEN: A potential Achilles heel for breast cancer cells
A highly collaborative team of researchers at the Medical University of South Carolina and Ohio State University report in Nature Communications that they have identified a novel pathway for connective tissue PTEN in breast cancer cell response to radiotherapy.
Computers equal radiologists in assessing breast density and associated breast cancer risk
Automated breast-density evaluation was just as accurate in predicting women's risk of breast cancer, found and not found by mammography, as subjective evaluation done by radiologists, in a study led by researchers at UC San Francisco and Mayo Clinic.
Blood test can effectively rule out breast cancer, regardless of breast density
A new study published in PLOS ONE demonstrates that Videssa® Breast, a multi-protein biomarker blood test for breast cancer, is unaffected by breast density and can reliably rule out breast cancer in women with both dense and non-dense breast tissue.
Study shows influence of surgeons on likelihood of removal of healthy breast after breast cancer dia
Attending surgeons can have a strong influence on whether a patient undergoes contralateral prophylactic mastectomy after a diagnosis of breast cancer, according to a study published by JAMA Surgery.
Young breast cancer patients undergoing breast conserving surgery see improved prognosis
A new analysis indicates that breast cancer prognoses have improved over time in young women treated with breast conserving surgery.
Read More: Breast Cancer News and Breast Cancer Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.