Nav: Home

Measles prevention -- how to pull the trigger for vaccination campaigns?

October 11, 2016

Measles is an extremely contagious disease that can cause serious health outcomes in children. Routine vaccination has greatly reduced measles deaths in recent years, but very high vaccination coverage is needed in all countries to prevent disease outbreaks. In a Research Article in PLOS Medicine, Justin Lessler of the Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA and colleagues describe a modeling study aimed at assessing the potential benefits of using supplementary vaccination campaigns triggered by measles outbreaks or by serological surveys of population immunity as part of a measles control strategy.

By carrying out simulations based on four scenarios capturing different levels of measles incidence, Lessler and colleagues estimate that supplemental vaccination campaigns triggered by disease outbreaks could prevent 28,613 cases (95% confidence interval [CI] 25,722-31,505) over 15 y in high-incidence settings, and 599 cases (95% CI 464-735) in the lowest-incidence setting examined. Vaccination campaigns prompted by serological surveys, in contrast, could prevent 89,173 cases (95% CI 86,768-91,577) and 744 (95% CI 612-876) cases in the highest- and lowest-incidence settings, respectively, but would need to occur annually in high-incidence settings.

This work was funded by the Bill and Melinda Gates Foundation (Award #705580-3) (JL, CJEM, and BTG); the RAPIDD program of the Science & Technology Directorate, Department of Homeland Security and the NIH Fogarty International Center (JL, CJEM, and BTG), and a grant from the Science and Technology Directorate, Department of Homeland Security (HSHQDC-12 C-00058) (BTG). BTG is a member of the leadership team for the RAPIDD program at the Fogarty International Center. This program is funded by the Science & Technology Directorate of the Department of Homeland Security, which had no role in the design, data collection, analysis, decision to publish or preparation of this manuscript.

Competing Interests:

The authors have declared that no competing interests exist.


Lessler J, Metcalf CJE, Cutts FT, Grenfell BT (2016) Impact on Epidemic Measles of Vaccination Campaigns Triggered by Disease Outbreaks or Serosurveys: A Modeling Study. PLoS Med 13(10): e1002144. doi:10.1371/journal.pmed.1002144

Author Affiliations:

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America
Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey, United States of America
Office of Population Research, Princeton University, Princeton, New Jersey, United States of America
Fogarty International Center, Bethesda, Maryland, United States of America
London School of Hygiene and Tropical Medicine, London, United Kingdom



Related Public Health Articles:

Public health guidelines aim to lower health risks of cannabis use
Canada's Lower-Risk Cannabis Use Guidelines, released today with the endorsement of key medical and public health organizations, provide 10 science-based recommendations to enable cannabis users to reduce their health risks.
Study clusters health behavior groups to broaden public health interventions
A new study led by a University of Kansas researcher has used national health statistics and identified how to cluster seven health behavior groups based on smoking status, alcohol use, physical activity, physician visits and flu vaccination are associated with mortality.
Public health experts celebrate 30 years of CDC's prevention research solutions for communities with health disparities
It has been 30 years since CDC created the Prevention Research Centers (PRC) Program, currently a network of 26 academic institutions across the US dedicated to moving new discoveries into the communities that need them.
Public health experts support federally mandated smoke-free public housing
In response to a new federal rule mandating smoke-free policies in federally funded public housing authorities, three public health experts applaud the efforts of the US Department of Housing and Urban Development to protect nonsmoking residents from the harmful effects of tobacco exposure.
The Lancet Public Health: UK soft drinks industry levy estimated to have significant health benefits, especially among children
The UK soft drinks industry levy, due to be introduced in April 2018, is estimated to have significant health benefits, especially among children, according to the first study to estimate its health impact, published in The Lancet Public Health.
Social sciences & health innovations: Making health public
The international conference 'Social Sciences & Health Innovations: Making Health Public' is the third event organized as a collaborative endeavor between Maastricht University, the Netherlands, and Tomsk State University, the Russian Federation, with participation from Siberian State Medical University (the Russian Federation).
Columbia Mailman School Awards Public Health Prize to NYC Health Commissioner Dr. Mary T.
Dr. Mary T. Bassett, Commissioner of the New York City Department of Health and Mental Hygiene, was awarded the Frank A.
Poor health literacy a public health issue
America's poor record on health literacy is a public health issue, but one that can be fixed -- not by logging onto the internet but by increased interaction with your fellow human beings, a Michigan State University researcher argues.
Despite health law's bow to prevention, US public health funding is dropping: AJPH study
Although the language of the Affordable Care Act emphasizes disease prevention -- for example, mandating insurance coverage of clinical preventive services such as mammograms -- funding for public health programs to prevent disease have actually been declining in recent years.
'Chemsex' needs to become a public health priority
Chemsex -- sex under the influence of illegal drugs -- needs to become a public health priority, argue experts in The BMJ this week.

Related Public Health Reading:

Best Science Podcasts 2019

We have hand picked the best science podcasts for 2019. Sit back and enjoy new science podcasts updated daily from your favorite science news services and scientists.
Now Playing: TED Radio Hour

Do animals grieve? Do they have language or consciousness? For a long time, scientists resisted the urge to look for human qualities in animals. This hour, TED speakers explore how that is changing. Guests include biological anthropologist Barbara King, dolphin researcher Denise Herzing, primatologist Frans de Waal, and ecologist Carl Safina.
Now Playing: Science for the People

#SB2 2019 Science Birthday Minisode: Mary Golda Ross
Our second annual Science Birthday is here, and this year we celebrate the wonderful Mary Golda Ross, born 9 August 1908. She died in 2008 at age 99, but left a lasting mark on the science of rocketry and space exploration as an early woman in engineering, and one of the first Native Americans in engineering. Join Rachelle and Bethany for this very special birthday minisode celebrating Mary and her achievements. Thanks to our Patreons who make this show possible! Read more about Mary G. Ross: Interview with Mary Ross on Lash Publications International, by Laurel Sheppard Meet Mary Golda...