Annals of Internal Medicine, Tip Sheet, October 17, 2000

October 16, 2000

Annals of Internal Medicine is published by the American College of Physicians-American Society of Internal Medicine (ACP-ASIM), an organization of more than 115,000 internal medicine physicians and medical students. The following highlights are not intended to substitute for articles as sources of information. For an embargoed fax of an article, call 1-800-523-1546, ext. 2656 or 215-351-2656. Full content of the issue is available on the Internet at http://www.annals.org on October 17, 2000.

Study finds colonoscopy cost-effective in screening for colorectal cancer
A study found that colonoscopy, compared to fecal occult blood tests (FOBT) and sigmoidoscopy, is the most cost-effective way to screen for colorectal cancer (Article, p. 573). FOBT detects blood in the stool; sigmoidoscopy allows examination of the rectum and lower colon; colonoscopy allows examination of the entire colon. Using a computer simulation, researchers considered administering FOBT annually, sigmoidoscopy every five years, and colonoscopy every 10 years beginning at age 50. They concluded that, despite its high total cost, colonoscopy reduces the death rate at relatively low "incremental" costs. It can prevent the cancer by removing precancerous polyps in the colon and can find colorectal cancer at early, more treatable stages, thus reducing future costs of cancer care. An editorial says the study shows that insurers will "pay now or pay later" (Editorial, p. 647). If Medicare, which pays for FOBT and flexible sigmoidoscopy, paid for colonoscopy, more lives would be saved and possibly at reduced cost, the editorial says.

Smoking is associated with kidney damage
A study of 7,476 nondiabetic people found that smokers had higher levels of a protein, albumin, in the urine and more abnormal kidney function than non-smokers (Article, p. 585). Former smokers had less albumin in the urine than smokers and no observable kidney abnormalities.

Better access to information about clinical trials in new registry on web
A new national registry of about 5,000 ongoing clinical trials is now available on the Web at http://clinicaltrials.gov (Academia and Clinic, p. 609). Information on each trial includes the location, criteria for participation, and contacts for enrolling in the trial.
-end-


American College of Physicians

Related Cancer Articles from Brightsurf:

New blood cancer treatment works by selectively interfering with cancer cell signalling
University of Alberta scientists have identified the mechanism of action behind a new type of precision cancer drug for blood cancers that is set for human trials, according to research published in Nature Communications.

UCI researchers uncover cancer cell vulnerabilities; may lead to better cancer therapies
A new University of California, Irvine-led study reveals a protein responsible for genetic changes resulting in a variety of cancers, may also be the key to more effective, targeted cancer therapy.

Breast cancer treatment costs highest among young women with metastic cancer
In a fight for their lives, young women, age 18-44, spend double the amount of older women to survive metastatic breast cancer, according to a large statewide study by the University of North Carolina at Chapel Hill.

Cancer mortality continues steady decline, driven by progress against lung cancer
The cancer death rate declined by 29% from 1991 to 2017, including a 2.2% drop from 2016 to 2017, the largest single-year drop in cancer mortality ever reported.

Stress in cervical cancer patients associated with higher risk of cancer-specific mortality
Psychological stress was associated with a higher risk of cancer-specific mortality in women diagnosed with cervical cancer.

Cancer-sniffing dogs 97% accurate in identifying lung cancer, according to study in JAOA
The next step will be to further fractionate the samples based on chemical and physical properties, presenting them back to the dogs until the specific biomarkers for each cancer are identified.

Moffitt Cancer Center researchers identify one way T cell function may fail in cancer
Moffitt Cancer Center researchers have discovered a mechanism by which one type of immune cell, CD8+ T cells, can become dysfunctional, impeding its ability to seek and kill cancer cells.

More cancer survivors, fewer cancer specialists point to challenge in meeting care needs
An aging population, a growing number of cancer survivors, and a projected shortage of cancer care providers will result in a challenge in delivering the care for cancer survivors in the United States if systemic changes are not made.

New cancer vaccine platform a potential tool for efficacious targeted cancer therapy
Researchers at the University of Helsinki have discovered a solution in the form of a cancer vaccine platform for improving the efficacy of oncolytic viruses used in cancer treatment.

American Cancer Society outlines blueprint for cancer control in the 21st century
The American Cancer Society is outlining its vision for cancer control in the decades ahead in a series of articles that forms the basis of a national cancer control plan.

Read More: Cancer News and Cancer Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.