Annals of Internal Medicine tip sheet for Oct. 19, 2004

October 18, 2004

1. Chronic Prostatitis and Pelvic Pain Not Reduced by Antibiotic or A-Blocker

A six-week study of 196 men with moderately severe symptoms of chronic prostate/chronic pelvic pain (CP/CPPS) found that neither of two commonly prescribed drugs, ciprofloxacin, an antibiotic, or tamsulosin, an a-receptor blocker, successfully relieved symptoms (Article, p. 581).

CP/CPPS is a common disorder in men, characterized primarily by pain in the pelvic region and sometimes lower urinary tract symptoms and sexual dysfunction. Its cause is not known, but it is usually treated with an antibiotic and/or a-receptor blocker.

An editorial writer says that the study clearly shows that antibiotics aren't useful but notes that some studies have shown improvement if a-receptor blockers are used for extended periods of time, e.g., three to six months (Editorial, p. 639).

* * *

2. Simple Exercises Help Many with Vertigo and Dizziness

Simple exercises markedly improved dizziness in a study of 170 adult patients assigned to either an exercise group or a usual-care group (Article, p. 598).

Patients in the exercise group met with a nurse, then at home recorded and performed daily exercises, such as rotating the head from left to right while keeping eyes open.

The exercise program, known as vestibular rehabilitation, is seldom offered in primary care situations, but an editorial writer says it is an easy, inexpensive and effective method to control balance, especially important in an aging population (Editorial, p. 641).

* * *

3. Study Searches for Best Blood Pressure Drugs for Black Patients

A meta-analysis of studies that looked at the effect of different antihypertensive drugs in black adults with hypertension found that commonly used drugs differ in ability to reduce blood pressure (Article, p.614).

Choice of drugs is important because black people are more likely to develop hypertension than others, and the disorder is often more severe, more resistant to treatment and more likely to be fatal at an earlier age.

Authors say that until future research clarifies issues such as the effects of different drugs on mortality, morbidity and diabetes as well as on blood pressure, physicians should prescribe antihypertensive drugs that have the lowest possible risk for side effects.

* * *

4. Survivors of Childhood Cancer Are at Risk for Subsequent Breast Cancer

In a study of 6,068 women who had childhood cancer, 95 subsequently developed breast cancer (Article, p. 590). At most risk were those who had been previously treated with chest radiation therapy, those with a family history of breast cancer or a personal history of thyroid disease.

* * *

Annals of Internal Medicine is published by the American College of Physicians, an organization of 116,000 internal medicine physicians and medical students. These highlights are not intended to substitute for articles as sources of information.

American College of Physicians

Related Breast Cancer Articles from Brightsurf:

Oncotarget: IGF2 expression in breast cancer tumors and in breast cancer cells
The Oncotarget authors propose that methylation of DVDMR represents a novel epigenetic biomarker that determines the levels of IGF2 protein expression in breast cancer.

Breast cancer: AI predicts which pre-malignant breast lesions will progress to advanced cancer
New research at Case Western Reserve University in Cleveland, Ohio, could help better determine which patients diagnosed with the pre-malignant breast cancer commonly as stage 0 are likely to progress to invasive breast cancer and therefore might benefit from additional therapy over and above surgery alone.

Partial breast irradiation effective treatment option for low-risk breast cancer
Partial breast irradiation produces similar long-term survival rates and risk for recurrence compared with whole breast irradiation for many women with low-risk, early stage breast cancer, according to new clinical data from a national clinical trial involving researchers from The Ohio State University Comprehensive Cancer Center - Arthur G.

Breast screening linked to 60 per cent lower risk of breast cancer death in first 10 years
Women who take part in breast screening have a significantly greater benefit from treatments than those who are not screened, according to a study of more than 50,000 women.

More clues revealed in link between normal breast changes and invasive breast cancer
A research team, led by investigators from Georgetown Lombardi Comprehensive Cancer Center, details how a natural and dramatic process -- changes in mammary glands to accommodate breastfeeding -- uses a molecular process believed to contribute to survival of pre-malignant breast cells.

Breast tissue tumor suppressor PTEN: A potential Achilles heel for breast cancer cells
A highly collaborative team of researchers at the Medical University of South Carolina and Ohio State University report in Nature Communications that they have identified a novel pathway for connective tissue PTEN in breast cancer cell response to radiotherapy.

Computers equal radiologists in assessing breast density and associated breast cancer risk
Automated breast-density evaluation was just as accurate in predicting women's risk of breast cancer, found and not found by mammography, as subjective evaluation done by radiologists, in a study led by researchers at UC San Francisco and Mayo Clinic.

Blood test can effectively rule out breast cancer, regardless of breast density
A new study published in PLOS ONE demonstrates that Videssa® Breast, a multi-protein biomarker blood test for breast cancer, is unaffected by breast density and can reliably rule out breast cancer in women with both dense and non-dense breast tissue.

Study shows influence of surgeons on likelihood of removal of healthy breast after breast cancer dia
Attending surgeons can have a strong influence on whether a patient undergoes contralateral prophylactic mastectomy after a diagnosis of breast cancer, according to a study published by JAMA Surgery.

Young breast cancer patients undergoing breast conserving surgery see improved prognosis
A new analysis indicates that breast cancer prognoses have improved over time in young women treated with breast conserving surgery.

Read More: Breast Cancer News and Breast Cancer Current Events is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to