Nav: Home

Pitt to lead trauma network, up to $90M in Department of Defense-funded trauma research

October 19, 2016

PITTSBURGH, Oct. 19, 2016 - The University of Pittsburgh Schools of the Health Sciences has been awarded a U.S. Department of Defense (DOD) contract that could lead to $90 million in research over the next decade to improve trauma care for both civilians and military personnel.

The contract will launch with a $10.8 million project to create a nationwide network of trauma systems and centers capable of conducting detailed research to improve military trauma care. The Linking Investigations in Trauma and Emergency Services (LITES) Network will include extensive data collection to obtain and link information covering pre-hospital care through recovery after discharge on potentially thousands of trauma cases across the country.

"Our immediate goal is to characterize what our network can do by obtaining intensive data from the pre-hospital and in-hospital settings, which is beyond what is normally obtained by trauma centers across the country," said Jason L. Sperry, M.D., M.P.H., principal investigator, professor of surgery and critical care medicine at Pitt's School of Medicine, and trauma surgeon at UPMC. "Our sense is that after approximately two years of accruing large amounts of data, we'll be able to launch subsequent projects at the DOD's request--including the gold standard: randomized clinical trials--to find out what approach to care works best to keep people who are injured in a trauma from dying."

In its initial project, the LITES Network is expected to provide epidemiological data on moderate and severe injuries in the U.S. and identify any regional variations in the types of injuries and the way they're managed.

"The LITES network will allow us to study the continuum of trauma care from the first emergency medical services contact through the emergency department and on to the operating rooms and intensive care units," said Frank X. Guyette, M.D., M.P.H., associate professor of emergency medicine in Pitt's School of Medicine, medical director of STAT MedEvac, and co-principal investigator of LITES. "The lessons learned through this project will teach us how to better care for ill and injured civilians and protect our soldiers in the future."

A recent National Academies of Sciences, Engineering and Medicine report determined that the lives of hundreds of U.S. service members could likely be saved in future wars if trauma care were optimal, and that those gains would lead to tens of thousands of civilian lives saved if such improvements were shared with U.S. trauma centers.

"That report set a bold goal to achieve zero preventable deaths after injury and minimal trauma-related disability," said Dr. Sperry. "Serendipitously, the LITES Network has the potential to spur research that will lead to clinical advancements to achieve that ambitious goal."

The University of Pittsburgh previously has collaborated with the University of Colorado and Oregon Health & Science University, and due to their integrated research approach and clinical trial experience, these three institutions will provide the trauma leadership necessary for the successful execution of the clinical trial network. The initial study also will use five other trauma centers: the University of Texas at Houston, Vanderbilt University, University of Louisville, Baylor College of Medicine and the University of Arizona. Additional trauma centers from across the country will be involved in subsequent studies, including the University of Pennsylvania, University of Utah, University of Texas Southwestern and the University of Florida. The Pitt Graduate School of Public Health's Epidemiology Data Center will be the data coordinating center, while the Multidisciplinary Acute Care Research Organization at Pitt will be the clinical coordinating center.

Unlike most multi-center studies of this magnitude, LITES Network projects will be made more efficient by relying on a central Institutional Review Board at Pitt. This will allow the network more flexibility to respond quickly to specific DOD project requests.

The Coalition for National Trauma Research, composed of six leading trauma-related organizations, will be a key partner in the project by providing expertise in advocacy and strategic planning.

The LITES Network contract follows an established track record of Pitt successfully producing valuable results for the DOD, including the Prehospital Air Medical Plasma Trial, the Study of Tranexamic Acid During Air Medical Prehospital Trial and the Traumatic Brain Injury Endpoints Development initiative.

In addition to Drs. Sperry and Guyette, core leadership for the LITES Network include Stephen R. Wisniewski, Ph.D., and David Okonkwo, M.D., Ph.D., both of Pitt; Ernest E. Moore, M.D., of the University of Colorado; and Martin A. Schrieber, M.D., of the Oregon Health and Science University. Barbara Early, B.S.N., of Pitt, will be the program administrator.

The research activities planned under Contract No. W81XWH-16-D-0024-0001 are supported by the U.S. Army Medical Research Acquisition Activity. The views expressed in this article are those of the authors and may not reflect the official policy or position of the Department of the Army, DOD or the U.S. Government.
-end-
About the University of Pittsburgh Schools of the Health Sciences

The University of Pittsburgh Schools of the Health Sciences include the schools of Medicine, Nursing, Dental Medicine, Pharmacy, Health and Rehabilitation Sciences and the Graduate School of Public Health. The schools serve as the academic partner to the UPMC (University of Pittsburgh Medical Center). Together, their combined mission is to train tomorrow's health care specialists and biomedical scientists, engage in groundbreaking research that will advance understanding of the causes and treatments of disease and participate in the delivery of outstanding patient care. Since 1998, Pitt and its affiliated university faculty have ranked among the top 10 educational institutions in grant support from the National Institutes of Health. For additional information about the Schools of the Health Sciences, please visit http://www.health.pitt.edu.

http://www.upmc.com/media

University of Pittsburgh Schools of the Health Sciences

Related Trauma Articles:

Childhood trauma affects the timing of motherhood
Women who have experienced childhood trauma become mothers earlier than those with a more stable childhood environment shows a new study conducted in collaboration between the University of Turku and the University of Helsinki in Finland.
Trauma relapse in a novel context may be preventable
Korea Brain Research Institute (KBRI, President: Pann-Ghill Suh) announced on February 10 that its research team led by Dr.
Paving the way to healing complex trauma
A major study led by researchers at La Trobe University in Australia has identified key themes that will be used to inform strategies to support Aboriginal and Torres Strait Islander parents in the first years of their children's lives.
Improving trauma pain outcomes
A 7-year prospective cohort study from the Corporal Michael J.
Emotional trauma and fear most likely cause of 'Havana Syndrome'
The cause of the mystery illness among US and Canadian diplomats in Havana is most likely to be emotional trauma and fear according to a leading sociologist and an expert in neurodegenerative diseases, writing in the Journal of the Royal Society of Medicine.
Making a 'to do' list for trauma docs
Researchers from Drexel's College of Computing & Informatics have been integrating a tablet-based checklist tool into the workflow of a pediatric trauma center and, over the course of 15 months, have shown that it doesn't hamper doctors' performance.
Children develop PTSD when they 'overthink' their trauma
A new study shows that children are more likely to suffer PTSD if they think their reaction to a traumatic event is not 'normal'.
Disparities in access to trauma centers
An analysis of census tract data for neighborhoods in America's three largest cities suggests black-majority neighborhoods are associated with disparities in access to trauma centers.
Psychotic experiences could be caused by trauma in childhood
Researchers at the University of Bristol have made stronger links between psychotic experiences and different types of trauma in childhood.
Is surgery the best option for penetrating kidney trauma?
SLU surgeon Sameer A. Siddiqui, M.D., and his research team examined patient records to study the best approach for renal trauma injuries.
More Trauma News and Trauma Current Events

Trending Science News

Current Coronavirus (COVID-19) News

Top Science Podcasts

We have hand picked the top science podcasts of 2020.
Now Playing: TED Radio Hour

Listen Again: Meditations on Loneliness
Original broadcast date: April 24, 2020. We're a social species now living in isolation. But loneliness was a problem well before this era of social distancing. This hour, TED speakers explore how we can live and make peace with loneliness. Guests on the show include author and illustrator Jonny Sun, psychologist Susan Pinker, architect Grace Kim, and writer Suleika Jaouad.
Now Playing: Science for the People

#565 The Great Wide Indoors
We're all spending a bit more time indoors this summer than we probably figured. But did you ever stop to think about why the places we live and work as designed the way they are? And how they could be designed better? We're talking with Emily Anthes about her new book "The Great Indoors: The Surprising Science of how Buildings Shape our Behavior, Health and Happiness".
Now Playing: Radiolab

The Third. A TED Talk.
Jad gives a TED talk about his life as a journalist and how Radiolab has evolved over the years. Here's how TED described it:How do you end a story? Host of Radiolab Jad Abumrad tells how his search for an answer led him home to the mountains of Tennessee, where he met an unexpected teacher: Dolly Parton.Jad Nicholas Abumrad is a Lebanese-American radio host, composer and producer. He is the founder of the syndicated public radio program Radiolab, which is broadcast on over 600 radio stations nationwide and is downloaded more than 120 million times a year as a podcast. He also created More Perfect, a podcast that tells the stories behind the Supreme Court's most famous decisions. And most recently, Dolly Parton's America, a nine-episode podcast exploring the life and times of the iconic country music star. Abumrad has received three Peabody Awards and was named a MacArthur Fellow in 2011.