Visualising potential outcome of cancer treatment

October 21, 2002

This release is also available in French, Spanish, Italian, and German.

A revolutionary new application of an imaging technique to predict the response to chemotherapy before treatment begins was announced today (21 October 2002). Dr Yael Mardor, from the Sheba Medical Centre, Israel, described the preliminary results in mice of the potential use of magnetic resonance imaging (MRI) technology at the European Society for Medical Oncology Congress in Nice, France.

The technique is called 'Diffusion-Weighted Magnetic Resonance Imaging' - DWMRI. It is sensitive to the different characteristics related to the water content of biological tissues. DWMRI has been recently studied in clinical trials as a means to measure the response to therapy after treatment has commenced but, said Dr Mardor, "This is the first time we have been able to demonstrate that it is possible to work out what might happen to a tumour before treatment has begun."

Using DWMRI, the researchers were able to visualise and measure the water characteristics in the tissues of mice with colon carcinoma before and after chemotherapy. They found a significant correlation in the water diffusion properties prior to treatment with the subsequent growth rate of the tumour.

There is a great deal of scientific interest in tissue characterisation for diagnosis and the prognosis of cancer treatment. "In the future, we hope that DWMRI will be a valuable tool in working out the best treatment program for patients with cancer," said Dr Mardor. "We are a long way away yet, but we are working on it."

European Society for Medical Oncology

Related Cancer Articles from Brightsurf:

New blood cancer treatment works by selectively interfering with cancer cell signalling
University of Alberta scientists have identified the mechanism of action behind a new type of precision cancer drug for blood cancers that is set for human trials, according to research published in Nature Communications.

UCI researchers uncover cancer cell vulnerabilities; may lead to better cancer therapies
A new University of California, Irvine-led study reveals a protein responsible for genetic changes resulting in a variety of cancers, may also be the key to more effective, targeted cancer therapy.

Breast cancer treatment costs highest among young women with metastic cancer
In a fight for their lives, young women, age 18-44, spend double the amount of older women to survive metastatic breast cancer, according to a large statewide study by the University of North Carolina at Chapel Hill.

Cancer mortality continues steady decline, driven by progress against lung cancer
The cancer death rate declined by 29% from 1991 to 2017, including a 2.2% drop from 2016 to 2017, the largest single-year drop in cancer mortality ever reported.

Stress in cervical cancer patients associated with higher risk of cancer-specific mortality
Psychological stress was associated with a higher risk of cancer-specific mortality in women diagnosed with cervical cancer.

Cancer-sniffing dogs 97% accurate in identifying lung cancer, according to study in JAOA
The next step will be to further fractionate the samples based on chemical and physical properties, presenting them back to the dogs until the specific biomarkers for each cancer are identified.

Moffitt Cancer Center researchers identify one way T cell function may fail in cancer
Moffitt Cancer Center researchers have discovered a mechanism by which one type of immune cell, CD8+ T cells, can become dysfunctional, impeding its ability to seek and kill cancer cells.

More cancer survivors, fewer cancer specialists point to challenge in meeting care needs
An aging population, a growing number of cancer survivors, and a projected shortage of cancer care providers will result in a challenge in delivering the care for cancer survivors in the United States if systemic changes are not made.

New cancer vaccine platform a potential tool for efficacious targeted cancer therapy
Researchers at the University of Helsinki have discovered a solution in the form of a cancer vaccine platform for improving the efficacy of oncolytic viruses used in cancer treatment.

American Cancer Society outlines blueprint for cancer control in the 21st century
The American Cancer Society is outlining its vision for cancer control in the decades ahead in a series of articles that forms the basis of a national cancer control plan.

Read More: Cancer News and Cancer Current Events is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to