Improvements in survival after dialysis in the elderly

October 22, 2007

The majority of patients starting dialysis as a result of chronic kidney disease are 65 years or older at the time of their first treatment, and many are over 75 years. Dr. Sarbjit Vanita Jassal and colleagues sought to calculate the mean life-expectancy of patients who began dialysis at either 65-74 years of age or at 75 years or more, and to identify where there was any change in survival probability or in the effect of comorbidities (such as diabetes or heart problems) in this patient population over the decade 1990 to 1999.

In this retrospective cohort study of data from the Canadian Organ Replacement Register, the researchers found that survival among 14 512 elderly patients who began dialysis between 1990 and 1999 improved over time, despite their increasing burden of comorbidity. Specifically, patients aged 65-74 years at the start of dialysis experienced a 23% improvement in survival and those aged 75 or more a 15% improvement. The authors conclude that age alone should not be used as a deterrent to initiating dialysis; rather, the decision should be made on an individual basis and other factors taken into account, including comorbidities, functional abilities and overall quality of life.
The paper associated with this press release can be found at the link below:

Canadian Medical Association Journal

Related Dialysis Articles from Brightsurf:

Immediate dialysis no better than wait-until-necessary approach, researchers find
In the largest international study of its kind, researchers at the University of Alberta and Toronto's St.

Predictors of 5-year mortality in young dialysis patients
The analysis published in NDT [1] evaluated for the first time the association of a large number of demographic, HD treatment and laboratory variables with mortality in patients on chronic hemodialysis treatment since childhood.

COVID-19 mortality alarmingly high in dialysis patients
Analysis of a Spanish experience shows that COVID-19 is frequent in hemodialysis patients, who appear to be at risk for worse outcome.

Survival following switch from urgent in-center hemodialysis to home dialysis
Few patients who start urgent and unplanned dialysis in clinical centers switch to home dialysis.

Is ownership of dialysis facilities associated with access to kidney transplants?
An analysis that included data for nearly 1.5 million patients with end-stage kidney disease looked at whether ownership of dialysis facilities was associated with patients' access to kidney transplants.

At-home dialysis improves quality of life
The rate of people starting voluntary at-home peritoneal dialysis rose from 15% to 34% over 10 years at Kaiser Permanente in Northern California, providing a convenient and safe way to manage advanced-stage kidney disease compared with center-based hemodialysis, according to research published today in JAMA Internal Medicine.

Hydration sensor could improve dialysis
Researchers from MIT and Massachusetts General Hospital have now developed a portable sensor that can accurately measure patients' hydration levels using a technique known as nuclear magnetic resonance (NMR) relaxometry.

Uncovering possible role of polyphosphate in dialysis-related amyloidosis
Researchers from Osaka University found that the low concentrations of the naturally occurring biopolymer, polyphosphate (polyP), induces amyloid formation from β2 microglobulin under both acidic and neutral conditions but by different mechanisms.

Study compares dialysis reimbursement around the globe
Dialysis reimbursement policies in most countries are focused on conventional in-center hemodialysis, although home hemodialysis and peritoneal dialysis might contribute to quality of life and cost savings.

Elderly patients on dialysis have a high risk of dementia
Older kidney disease patients who are sick enough to require the blood-filtering treatment known as dialysis are at high risk of dementia, including Alzheimer's disease, according to a study led by scientists at Johns Hopkins Bloomberg School of Public Health.

Read More: Dialysis News and Dialysis Current Events is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to