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Optical scanner shows potential for real-time 3-D breast cancer screening

October 22, 2015

The results are reported today, 23rd October 2015, in the journal Biomedical Physics & Engineering Express.

The device, developed primarily at Florida International University, uses a near-infrared laser diode source to produce an image of the breast tissues.

One advantage presented by the device is that it is more adaptable to breast shape and density, and that it allows imaging of the chest wall regions, which are harder to image with conventional techniques.

"The women scanned always commented on how comfortable it was to be scanned by our device - many of them said that they didn't feel anything" explains Sarah Erickson-Bhatt, an author on the paper.

The device builds an image of the tissue by mapping the optical absorption, which is altered by the concentration of haemoglobin - the protein in red blood cells. Regions with higher concentrations of haemoglobin may indicate higher blood flow due to an abnormality such as a tumour.

The optical analysis developed offers several benefits over mammography, with no ionising radiation dose and fewer issues imaging dense tissues.

"Eventually, we hope that physicians will be able to use this for real-time imaging of breast tissues as part of regular visits by the patients" adds Anu Godavarty, also an author of the paper. "We're current working on the mathematical tools required to process the images and produce 3D tomographic images, in order to determine tumour size and depth."

The researchers' on-going efforts involve extensive clinical work to demonstrate the capability of the device to pre-screen for any breast abnormality, followed by seeking FDA approvals prior to clinical use.
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A draft version of the paper is available here: https://www.dropbox.com/s/vb814agm5fj6a7o/BPEX%20-%20100048.pdf?dl=0

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Non-invasive Surface Imaging of Breast Cancer in Humans using a Hand-held Optical Imager


The published version of the paper 'Non-invasive Surface Imaging of Breast Cancer in Humans using a Hand-held Optical Imager' (Biomedical Physics & Engineering Express 1 045001) will be freely available online from Friday 23 October. It will be available at http://iopscience.iop.org/2057-1976/1/4/045001.

DOI: 10.1088/2057-1976/1/4/045001

Biomedical Physics & Engineering Express

Biomedical Physics & Engineering Express is a broad, inclusive, rapid review journal devoted to publishing new research in all areas of biomedical engineering, biophysics and medical physics. The journal has a special emphasis on interdisciplinary work between these fields, and is published in an online only format.

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