Nav: Home

CCNY study breaks Förster resonant energy transfer (FRET) distance limit

October 25, 2018

Using engineered nanocomposite structures called metamaterials, a City College of New York-led research team reports the ability to measure a significant increase in the energy transfer between molecules. Reported in the journal ACS Photonics, this breakthrough breaks the Förster resonance energy transfer (FRET) distance limit of ~10-20 nanometers, and leads to the possibility of measuring larger molecular assemblies.

And since FRET is a staple technique in many biological and biophysical fields, this new development could benefit pharmaceuticals, for instance.

"Energy transfer between molecules plays a central role in phenomena such as photosynthesis and is also used as a spectroscopic ruler for identifying structural changes of molecules," said Vinod Menon, professor of physics in City College's Division of Science. "However, the process of energy transfer is usually limited in the distance over which it occurs, typically reaching 10 to 20 nm."

But in the study reported by Menon's research group in ACS Photonics, the authors demonstrate significant increase in the energy transfer distance (> 15x) - reaching ~ 160 nm. This is accomplished by using a metamaterial that undergoes a topological transition.

The present work sets the stage for the use of spectroscopic rulers for studying a wide array of larger molecular systems which has not been previously possible using standard FRET technique.
The Menon group comprised CCNY physics majors Rahul Deshmukh and Tal Galfsky (both graduate students) and Emaad Khwaja (undergraduate). Collaborators included the theory groups of Girish Agarwal (Texas A&M University) and Svend-Age Biehs (Carl von Ossietzky University, Germany). The work at CCNY was supported by the National Science Foundation's Division of Materials Research and the U.S. Department of Energy's Office of Basic Energy Sciences.

City College of New York

Related Physics Articles:

Diamonds coupled using quantum physics
Researchers at TU Wien have succeeded in coupling the specific defects in two such diamonds with one another.
The physics of wealth inequality
A Duke engineering professor has proposed an explanation for why the income disparity in America between the rich and poor continues to grow.
Physics can predict wealth inequality
The 2016 election year highlighted the growing problem of wealth inequality and finding ways to help the people who are falling behind.
Physics: Toward a practical nuclear pendulum
Researchers from Ludwig-Maximilians-Universitaet (LMU) Munich have, for the first time, measured the lifetime of an excited state in the nucleus of an unstable element.
Flowers use physics to attract pollinators
A new review indicates that flowers may be able to manipulate the laws of physics, by playing with light, using mechanical tricks, and harnessing electrostatic forces to attract pollinators.
More Physics News and Physics Current Events

Best Science Podcasts 2019

We have hand picked the best science podcasts for 2019. Sit back and enjoy new science podcasts updated daily from your favorite science news services and scientists.
Now Playing: TED Radio Hour

Do animals grieve? Do they have language or consciousness? For a long time, scientists resisted the urge to look for human qualities in animals. This hour, TED speakers explore how that is changing. Guests include biological anthropologist Barbara King, dolphin researcher Denise Herzing, primatologist Frans de Waal, and ecologist Carl Safina.
Now Playing: Science for the People

#534 Bacteria are Coming for Your OJ
What makes breakfast, breakfast? Well, according to every movie and TV show we've ever seen, a big glass of orange juice is basically required. But our morning grapefruit might be in danger. Why? Citrus greening, a bacteria carried by a bug, has infected 90% of the citrus groves in Florida. It's coming for your OJ. We'll talk with University of Maryland plant virologist Anne Simon about ways to stop the citrus killer, and with science writer and journalist Maryn McKenna about why throwing antibiotics at the problem is probably not the solution. Related links: A Review of the Citrus Greening...