Mentally ill die many years earlier than others

October 25, 2019

Based on register data from 7,4 million persons living in Denmark between 1995 and 2015, the new nationwide study from the National Centre for Register-based Research at Aarhus BSS, Aarhus University, is the most comprehensive study ever done on mortality in persons with mental disorders.

"It is well known that people with mental disorders die earlier than the general population. However, for the first time, we present a comprehensive study where we investigate mortality in specific types of mental disorders. We have used new ways to measure life expectancy that are more accurate than the ones used in the past," says Dr. Oleguer Plana-Ripoll, who is a postdoctoral researcher at the National Centre for Register-based Research, Aarhus University, and the lead author of the study.

The results have just been published in The Lancet, which is one of the world's most prestigious medical journals.

The new study explores mortality for those with different types of mental disorders. The researchers were able to explore anonymous data within Danish health registers - the findings provide new insights into how mental disorders impact on the lives of people with disorders such as depression, anxiety disorders and substance use disorders.

"Most studies provide "mortality rates", which is a way to estimate the risk of death in those with mental disorders compared to those without. We investigated how mortality rates changed for each type of disorder, for each age, for males and females. In addition to looking at premature mortality, we were able to explore specific causes of death such as cancer, diabetes and suicide," says Oleguer Plana-Ripoll.

"The risk of an early death was higher for people with mental disorders across all ages," Oleguer Plana-Ripoll adds.

When looking at differences in life expectancy, the researchers found that men and women with mental disorders on average had life expectancies respectively 10 and 7 years shorter after the diagnosis of the disease compared to an overall Danish person of the same age.

"For example, people with depression or another type of mood disorder, which are among the most common mental disorders, had higher mortality rates. Apart from an increased risk of death due to suicide, we also confirm an increased risk of death due to somatic conditions such as cancer, respiratory diseases, diabetes etc. We found that men and women with mood disorders experienced life expectancies respectively 7.9 and 6.2 years shorter after disease diagnosis compared to the overall Danish person with the same age," says Dr Plana-Ripoll.

The study was completed as part of the Niels Bohr Professorship research programme at Aarhus University, which is led by Professor John McGrath. Funded by the Danish National Research Foundation, this research aims to explore innovative methods related to psychiatric epidemiology. According to John McGrath the research reveals worrying aspects of mortality among people with mental disorders.

"For example: we found an unusual pattern in men with a mental disorder. Contrary to our expectations, when we looked at life expectancy, they lost relatively few years of life due to cancer-related deaths compared to the general population. This was because, although they have a higher risk of dying from cancer, they are much more likely to die from cardiovascular and lung disorder at a younger age compared to the general population. This is a new and rather disappointing finding.", says Professor John McGrath.

"Our study emphasises the urgent need to improve general health for people with mental disorders, "John McGrath adds.
-end-


Aarhus University

Related Mortality Articles from Brightsurf:

Being in treatment with statins reduces COVID-19 mortality by 22% to 25%
A research by the Universitat Rovira i Virgili (URV) and Pere Virgili Institut (IISPV) led by LluĂ­s Masana has found that people who are being treated with statins have a 22% to 25% lower risk of dying from COVID-19.

Mortality rate higher for US rural residents
A recent study by Syracuse University sociology professor Shannon Monnat shows that mortality rates are higher for U.S. working-age residents who live in rural areas instead of metro areas, and the gap is getting wider.

COVID-19, excess all-cause mortality in US, 18 comparison countries
COVID-19 deaths and excess all-cause mortality in the U.S. are compared with 18 countries with diverse COVID-19 responses in this study.

New analysis shows hydroxychloroquine does not lower mortality in COVID-19 patients, and is associated with increased mortality when combined with the antibiotic azithromycin
A new meta-analysis of published studies into the drug hydroxychloroquine shows that it does not lower mortality in COVID-19 patients, and using it combined with the antibiotic azithromycin is associated with a 27% increased mortality.

Hydroxychloroquine reduces in-hospital COVID-19 mortality
An Italian observational study contributes to the ongoing debate regarding the use of hydroxychloroquine in the current pandemic.

What's the best way to estimate and track COVID-19 mortality?
When used correctly, the symptomatic case fatality ratio (sCFR) and the infection fatality ratio (IFR) are better measures by which to monitor COVID-19 epidemics than the commonly reported case fatality ratio (CFR), according to a new study published this week in PLOS Medicine by Anthony Hauser of the University of Bern, Switzerland, and colleagues.

COVID-19: Bacteriophage could decrease mortality
Bacteriophage can reduce bacterial growth in the lungs, limiting fluid build-up.

COPD and smoking associated with higher COVID-19 mortality
Current smokers and people with chronic obstructive pulmonary disease (COPD) have an increased risk of severe complications and higher mortality with COVID-19 infection, according to a new study published May 11, 2020 in the open-access journal PLOS ONE by Jaber Alqahtani of University College London, UK, and colleagues.

Highest mortality risks for poor and unemployed
Large dataset shows that income, work status and education have a clear influence on mortality in Germany.

Addressing causes of mortality in Zambia
Despite the fact that people in sub-Saharan Africa are now living longer than they did two decades ago, their average life expectancy remains below that of the rest of the world population.

Read More: Mortality News and Mortality Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.