IC-medtech licenses promising cancer therapeutic from Summa Health System

October 26, 2004

(Akron, Ohio) In September 2001, researchers at Summa Health System in Akron, Ohio reported that moderate doses of the vitamins C and K3 were eliminating many types of cancer cells including prostate, bladder, renal and ovarian. Today, only three years later, the results of Summa's cancer research is being licensed and under a new name, ApatoneTM. Clinical trials of the drug could begin as soon as next month at Summa Health System and other hospitals across the nation.

Indian Creek Medical Technologies, LLC has exclusively licensed Apatone, the novel anti-cancer therapeutic treatment first discovered by James M. Jamison, Ph.D. and Jack L. Summers, M.D, Ph.D, both of Summa Health System, in collaboration with Jacques Gilloteaux, DSc, and Henryk Taper, M.D., Ph.D. of Brussels, Belgium. The Summa team has been working collaboratively with Gilloteaux and Taper for nine years conducting extensive experimentation and now Summers and Jamison are excited by this next step with IC-MedTech.

"What is so significant about our study is that through out research of cancer cells, we have discovered a new form of cell death, never before reported," said Summers.

"We found early on that the combination of vitamins C and K3 seek out tumor cells and appear to leave normal cells unaffected," Summers explained. "The dying cells undergo a new flow of self-destruction in which the cell literally cuts itself into small pieces. This discovery was the first of its kind and to this point, cells were considered to die only by apoptosis (programmed cell death) or necrosis (toxic cell death or injury.)"

According to Tom Miller, CEO of IC-MedTech, his company is excited about the possibilities this drug could bring to cancer patients. "The research is substantial and shows that Apatone leverages a novel mechanism of action that shows strong promise as a clinical candidate to be developed for a variety of cancers."

A practical version of the chemo-adjunct based on low toxicity compounds to improve safety has been developed for use in clinical trials which are already underway. The treatment can be administered by intravenously (through a vein), intraperitoneally (through abdomen) or orally and it has been shown to enhance the performance of at least six different chemotherapeutic drugs (adriamycin, asparaginase, cyclophosphamide, 5-fluorouracil, oncovin and procarbazine).

Results of the research have been presented in more than 100 papers, abstracts and presentations with more than forty peer reviewed articles appearing in such publications as Cancer, Cancer Research, Anticancer Research, Cancer Chemotherapy and Pharmacology, Life Sciences, Journal of Nutrition, Tissue and Cell, Biochemical Pharmacology, Journal of Scanning Microscopy, Microscopy and Microanalysis and other.
-end-
About IC-MedTech
Founded in 2004, IC-MedTech is dedicated to the development of novel technologies and biotherapeutics to treat cancer and improve human health. IC-MedTech is currently developing Apatone together with a prognostic SADA (Serum Alkaline DNase Activity) test kit to enhance clinical treatment of a wide variety of cancers. For more information email info@ic-medtech.com.

About Summa Health System
Summa Health System is one of the largest organized delivery systems in Ohio. Encompassing a network of hospitals, community health centers, a health plan, a physician-hospital organization, research and a foundation, Summa is nationally renowned for excellence in patient care and for exceptional approaches to health care delivery. Summa's clinical services are consistently recognized by U.S. News and World Report, Solucient and Healthgrades. For more information, visit www.summahealth.org.

Note to Reporters and Editors: Dr. Jack Summers and Dr. James Jamison from Summa Health System and Tom Miller from IC-MedTech are available for interviews. Call Heather Phillips, Public Relations Manager from Summa to schedule an interview.

Summa Health System

Related Cancer Articles from Brightsurf:

New blood cancer treatment works by selectively interfering with cancer cell signalling
University of Alberta scientists have identified the mechanism of action behind a new type of precision cancer drug for blood cancers that is set for human trials, according to research published in Nature Communications.

UCI researchers uncover cancer cell vulnerabilities; may lead to better cancer therapies
A new University of California, Irvine-led study reveals a protein responsible for genetic changes resulting in a variety of cancers, may also be the key to more effective, targeted cancer therapy.

Breast cancer treatment costs highest among young women with metastic cancer
In a fight for their lives, young women, age 18-44, spend double the amount of older women to survive metastatic breast cancer, according to a large statewide study by the University of North Carolina at Chapel Hill.

Cancer mortality continues steady decline, driven by progress against lung cancer
The cancer death rate declined by 29% from 1991 to 2017, including a 2.2% drop from 2016 to 2017, the largest single-year drop in cancer mortality ever reported.

Stress in cervical cancer patients associated with higher risk of cancer-specific mortality
Psychological stress was associated with a higher risk of cancer-specific mortality in women diagnosed with cervical cancer.

Cancer-sniffing dogs 97% accurate in identifying lung cancer, according to study in JAOA
The next step will be to further fractionate the samples based on chemical and physical properties, presenting them back to the dogs until the specific biomarkers for each cancer are identified.

Moffitt Cancer Center researchers identify one way T cell function may fail in cancer
Moffitt Cancer Center researchers have discovered a mechanism by which one type of immune cell, CD8+ T cells, can become dysfunctional, impeding its ability to seek and kill cancer cells.

More cancer survivors, fewer cancer specialists point to challenge in meeting care needs
An aging population, a growing number of cancer survivors, and a projected shortage of cancer care providers will result in a challenge in delivering the care for cancer survivors in the United States if systemic changes are not made.

New cancer vaccine platform a potential tool for efficacious targeted cancer therapy
Researchers at the University of Helsinki have discovered a solution in the form of a cancer vaccine platform for improving the efficacy of oncolytic viruses used in cancer treatment.

American Cancer Society outlines blueprint for cancer control in the 21st century
The American Cancer Society is outlining its vision for cancer control in the decades ahead in a series of articles that forms the basis of a national cancer control plan.

Read More: Cancer News and Cancer Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.