New growth charts developed for US children with Down syndromeOctober 27, 2015
Pediatric researchers have developed the first set of growth charts for U.S. children with Down syndrome since 1988. These new charts provide an important tool for pediatricians to evaluate growth milestones for children and adolescents with this condition. With these new charts, pediatricians will be able to compare each patient's growth patterns with peers of the same age and sex who have Down syndrome.
"Growth is a good indicator of a child's health and well-being, so it's an essential part of the pediatric examination," said study leader Babette S. Zemel, Ph.D., director of the Nutrition and Growth Laboratory at The Children's Hospital of Philadelphia (CHOP). "Children with Down syndrome grow differently from other children, so it is important to have growth charts that reflect their unique growth pattern."
The study appeared online Oct. 26 in Pediatrics.
The study project, the Down Syndrome Growing Up Study (DSGS), was funded by a four-year, $1.2 million grant to CHOP from the Centers for Disease Control and Prevention (CDC).
Down syndrome, a multisystem genetic disorder resulting from an extra copy of chromosome 21, occurs in about one in 700 U.S. births. Doctors and parents have long known that children with Down syndrome tend to grow more slowly and are shorter than most other children.
Thanks to medical advances and improved access to care, overall health and well-being has improved for these patients; for example, life expectancy has increased from 35 years in 1985 to 53 years in 2007. This study investigated whether growth patterns have also improved.
The researchers followed 637 participants, up to age 20, recruited from the Trisomy 21 Program at CHOP and from community locations and pediatric practices, mostly in the greater Philadelphia area, between Jan. 2010 and July 2013. All the participants were in their usual state of health at the times of measurement and, on average, had three study visits at which measurements were taken.
Children under age three showed marked improvements in weight gain compared to the 1988 U.S. growth charts for children with Down syndrome. Improvements in height, reflecting taller stature, occurred mainly in males aged two to 20, relative to the earlier charts. In general, the DSGS charts were consistent with charts from U.K. children with Down syndrome, published in 2002.
The DSGS team also created the first-ever body mass index (BMI) charts for children with Down syndrome. The researchers noted that the charts do not represent an ideal distribution of BMI, but only describe BMI distribution among their study participants. They added that further investigations should determine how to use the BMI charts to screen patients for excess body fat and associated health symptoms.
"These charts more accurately reflect the growth of contemporary children with Down syndrome living in the U.S.," said Zemel. She added, "It is clear that growth has improved for infants and toddlers with Down syndrome over the past few decades, and that males are taller. The new BMI charts will be helpful for evaluating excess weight gain, which is mainly a concern as children advance through the teenage years. Ongoing research at CHOP, led by Dr. Andrea Kelly, and at Children's National Health System, led by Dr. Sheela Magge, will help determine if there are health consequences of excess weight in teens with Down syndrome."
Zemel's co-authors were Mary Pipan, M.D., Virginia A. Stallings, M.D., Waynitra Hall, M.S., Kim Schadt, MSN, all from CHOP; and David S. Freedman, Ph.D., and Phoebe Thorpe, M.D., MPH, both of the CDC.
"Growth Charts for Children with Down Syndrome in the U.S.," Pediatrics, published online Oct. 26, 2015. http://doi.org/10.1542/peds.2015-1652d
About The Children's Hospital of Philadelphia: The Children's Hospital of Philadelphia was founded in 1855 as the nation's first pediatric hospital. Through its long-standing commitment to providing exceptional patient care, training new generations of pediatric healthcare professionals and pioneering major research initiatives, Children's Hospital has fostered many discoveries that have benefited children worldwide. Its pediatric research program is among the largest in the country. In addition, its unique family-centered care and public service programs have brought the 535-bed hospital recognition as a leading advocate for children and adolescents. For more information, visit http://www.chop.edu.
Children's Hospital of Philadelphia
Related Health Articles:
Canada's Lower-Risk Cannabis Use Guidelines, released today with the endorsement of key medical and public health organizations, provide 10 science-based recommendations to enable cannabis users to reduce their health risks.
Offering comprehensive health insurance plans with low deductibles and co-pay in exchange for higher annual premiums seems like a good value for the risk averse, and a profitable product for insurance companies.
Increasing temperatures, water scarcity, availability of agricultural land, biodiversity loss and climate change threaten to reverse health gains seen over the last century.
Repeal of key provisions of the Affordable Care Act, combined with a failure to renew critical funding streams, would result in catastrophic funding losses for community health centers-forcing these safety net providers to cut back on services, lay off staff or shut down clinical sites, according to a report published today.
A new study led by a University of Kansas researcher has used national health statistics and identified how to cluster seven health behavior groups based on smoking status, alcohol use, physical activity, physician visits and flu vaccination are associated with mortality.
A tailored preventive oral health intervention significantly improved the cleanliness of teeth and dentures among elderly home care clients.
Findings published in the journal Behavioral Ecology reveal that skin with yellow and red pigments is perceived as more attractive in Caucasian males, but this skin coloring does not necessarily signal actual good health.
The January issue of Health Affairs includes a study that explores a much-discussed issue in global health: the role of governance in improving health, which is widely recognized as necessary but is difficult to tie to actual outcomes.
In collaboration with West Health, the University of Rochester is hosting the third annual d.health Summit, a forum for health care and technology leaders, entrepreneurs, senior care advocates and policymakers to exchange ideas, create new partnerships, and foster disruptive technological and process innovations to improve the lives of the nation's aging population.
The federal Affordable Care Act is intended to make it easier for individuals to buy health insurance, but are the uninsured equipped to navigate the choices faced in the insurance marketplace?
Related Health Reading:
The New Health Rules: Simple Changes to Achieve Whole-Body Wellness
by Frank Lipman M.D. (Author), Danielle Claro (Author)
New York Times Bestseller
Frank Lipman, M.D., is “at the vanguard of a revolutionary way to deliver medical care” (O, The Oprah Magazine). A leading expert in the field of functional medicine, Dr. Lipman focuses on the root causes of illness and guides his patients to the deepest, most lasting sources of wellness. In this book, he and coauthor Danielle Claro make life-changing health advice available to all. Their book offers the cutting-edge secrets to optimal health in a stylish, lushly illustrated format—a spoonful of beauty to help the wellness tips... View Details
A More Excellent Way, Be in Health: Spiritual Roots of Disease, Pathways to Wholeness (w/DVD)
by Henry W. Wright (Author)
The root of psychological and biological disease is spiritual. Pastor Henry W. Wright not only equips the church to defeat sickness, but he also demystifies it by showing, from God's perspective, why mankind has disease in the first place. The problem is not that God cannot heal disease or does not want to; the problem is that mankind does not understand disease.God's perfect will is not to heal you; His perfect will is that you won't get sick. A More Excellent Way is a valuable resource in assisting spiritual leaders, healthcare professionals, and all individuals in understanding the... View Details
Dr. Lani's No-Nonsense Bone Health Guide: The Truth About Density Testing, Osteoporosis Drugs, and Building Bone Quality at Any Age
by Lani Simpson DC CCD (Author), Claude Arnaud MD FACE (Foreword)
Part whistle-blower book, part bone health bible, Dr. Lani’s No-Nonsense Bone Health Guide is the first consumer book to expose the shocking difficulty of getting an accurate bone density reading and the serious risks of long-term use of osteoporosis medications, which are often prescribed based on inaccurate readings. In addition to this vital information about bone density testing, Dr. Lani Simpson cuts through the confusion and inaccuracies surrounding osteoporosis and explains what readers can do now to build and maintain healthy bones for life. Dr. Simpson shares her... View Details
The Men's Health Big Book of Exercises: Four Weeks to a Leaner, Stronger, More Muscular You!
by Adam Campbell MS CSCS (Author)
Revised edition includes 100 new exercises!
The Men’s Health Big Book of Exercises is the essential workout guide for anyone who wants a better body. As the most comprehensive collection of exercises ever created, this book is a body-shaping power tool for both beginners and long-time lifters alike. This book contains hundreds of useful tips, the latest findings in exercise science, and cutting-edge workouts from the world's top trainers.
Backed by the authority of Men's Health magazine, this updated and revised edition features 100 new fat-loss exercises... View Details
The South Asian Health Solution: A Culturally Tailored Guide to Lose Fat, Increase Energy and Avoid Disease
by Ronesh Sinha MD (Author)
The South Asian Health Solution is the first book to provide an ancestral health-based wellness plan culturally tailored for those of South Asian ancestry living in India, the United States and across the world – a population identified as being at the highest risk for heart disease, diabetes, obesity, and related conditions. Dr. Ronesh Sinha, an internal medicine specialist in California’s Silicon Valley, sees high risk South Asian patients and runs education and wellness programs for corporate clients. He has taken many South Asians out of the high risk, high body mass... View Details
The Swiss Secret to Optimal Health: Dr. Rau's Diet for Whole Body Healing
by Thomas Rau (Author), Susan M. Wyler (Author)
Now in paperback: a world-renowned physician shares the secrets that draw international clients to his clinic.
For almost 50 years, people have traveled to the Paracelsus Clinic in the Swiss Alps. There, Dr. Thomas Rau's unique diet rejuvenates his clients, while preventing and curing illness. Lauded as "the Mozart of medicine," Dr. Rau is the world's foremost practitioner of biological medicine. At last, he reveals his unique Swiss health plan- a proven program based on the latest medical research that will:
? Purify the body
? Regulate pH balance
? Strengthen... View Details
Eat For Health
by Joel Fuhrman (Author)
Dr. Fuhrman's scientifically proven system enables you to finally conquer your cravings and food addictions, while steering your taste buds toward healthier food choices. But be aware of the side effects....you may experience reversal of diseases such as heart disease, headaches, allergies, high blood pressure and diabetes, and you will feel better than ever before! This book includes Dr. Fuhrman's ANDI food scoring system, with three phases of meal plans and 150 fantastic recipes. Start where you are comfortable and progress at your own pace or jump right into phase three to maximize weight... View Details
Motivational Interviewing in Health Care: Helping Patients Change Behavior (Applications of Motivational Interviewing)
by Stephen Rollnick (Author), William R. Miller (Author), Christopher C. Butler (Author)
Much of health care today involves helping patients manage conditions whose outcomes can be greatly influenced by lifestyle or behavior change. Written specifically for health care professionals, this concise book presents powerful tools to enhance communication with patients and guide them in making choices to improve their health, from weight loss, exercise, and smoking cessation, to medication adherence and safer sex practices. Engaging dialogues and vignettes bring to life the core skills of motivational interviewing (MI) and show how to incorporate this brief evidence-based approach... View Details
Dr. A's Habits of Health: The Path to Permanent Weight Control & Optimal Health
by Dr. Wayne Scott Andersen (Author)
Go from surviving to thriving! If you've ever tried to lose weight only to gain it back, Dr. A's Habits of Health offers a life-changing breakthrough that shows you not only how to reach and maintain your healthy weight, but how to create a life of renewed vibrancy, health, and spirit all under the easy-to-follow guidance of one of America s most esteemed and compassionate practitioners of weight loss and optimal health. Join thousands of people worldwide who've gone from discouragement to confidence, from depletion to unimaginable vitality and discover how you can live better, happier, and... View Details