Frailty may lower kidney failure patients' likelihood of receiving a transplant

October 27, 2018

San Diego, CA (October 27, 2018) -- Frailty is associated with lower likelihoods of being placed on the kidney transplant waitlist and of receiving a transplant, according to a study that will be presented at ASN Kidney Week 2018 October 23-October 28 at the San Diego Convention Center.

To investigate whether frailty in patients with kidney failure may affect their likelihood of receiving a kidney transplant, Christine Haugen, MD (Johns Hopkins Hospital) and her colleagues studied 7078 potential kidney transplant candidates from 2009 to 2017. Patients were considered frail if they had 3 or more of the following components: unintentional weight loss, decreased grip strength, slowed walking speed, and low activity.

Frail participants were 38% less likely to be listed for transplantation, had nearly twofold increased risk of dying while on the transplant waitlist mortality, and underwent transplantation at a 35% lower rate than nonfrail participants.

"Prehabilitation may be a useful tool to increase physiologic reserve and subsequently improve access to kidney transplantation among frail patients," said Dr. Haugen.
-end-
Study: "Frailty and Age Disparities in Access to Kidney Transplantation"

ASN Kidney Week 2018, the largest nephrology meeting of its kind, will provide a forum for more than 13,000 professionals to discuss the latest findings in kidney health research and engage in educational sessions related to advances in the care of patients with kidney and related disorders. Kidney Week 2018 will take place October 23 - October 28 at the San Diego Convention Center.  

Since 1966, ASN has been leading the fight to prevent, treat, and cure kidney diseases throughout the world by educating health professionals and scientists, advancing research and innovation, communicating new knowledge, and advocating for the highest quality care for patients. ASN has more than 20,000 members representing 131 countries. For more information, please visit http://www.asn-online.org.

American Society of Nephrology

Related Kidney Transplant Articles from Brightsurf:

The effects of social determinants of health on kidney transplant candidates
Social determinants of health are associated with patient-reported outcomes in adults who are eligible to undergo kidney transplantation evaluations.

Tailored education system to benefit kidney transplant patients
Researchers find their computer-tailored education system, 'Your Path to Transplant' increases knowledge and readiness to pursue kidney transplant.

Kidney transplant, the cost of accounting for patients' preferences
Taking into account patients' preferences can help speed up the organ allocation process and improve the life quality of the recipients, as shown by a joint study conducted by Ca' Foscari University and the University of Padua

New hope for kidney revival for transplant
Cell therapy delivered directly to the kidney can revive a 'marginal' organ, improving function and could offer new hope for providing more kidneys for transplant.

Are kidney transplant patients at higher risk? The European experience
The risk of death is relatively high in kidney transplant patients admitted to hospital with COVID-19.

The economic burden of kidney transplant failure in the United States
A recent analysis published in the American Journal of Transplantation estimates that for the average US patient who has undergone kidney transplantation, failure of the transplanted organ (graft failure) will impose additional medical costs of $78,079 and a loss of 1.66 quality-adjusted life years.

Mixed chimerism improves long-term kidney transplant outlook
Mixed chimerism - the continued mixing of donor and recipient blood cells following a transplant of blood progenitor cells - could improve outcomes for kidney transplant recipients, according to a new clinical study in about 50 patients.

Kidney paired donation is an excellent option for transplant candidates
An analysis compared transplant recipients who received kidneys through national kidney paired donation and those who received kidneys from other living donors (such as relatives, friends or other paired exchange mechanisms).

Mediterranean diet may help preserve the kidney health of transplant recipients
In a study of kidney transplant recipients, those with higher adherence to the Mediterranean diet were less likely to experience kidney function loss.

New blood test can detect rejection by antibodies after kidney transplant
A group of European scientists led by KU Leuven has found a biomarker that can identify patients with symptoms of kidney rejection symptoms after a transplant as a result of antibodies.

Read More: Kidney Transplant News and Kidney Transplant Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.