Moderate alcohol consumption increases bone mineral density in elderly women

October 31, 2000

In a study of 489 post-menopausal women, moderate drinkers had significantly higher bone mineral density (BMD) than their nondrinking counterparts, according to research by Rapuri et al. published in The American Journal of Clinical Nutrition. Although the bone-protective effects of alcohol have been noted in previous research, this study provides new evidence that moderate alcohol consumption appears to decrease the rate of bone turnover. This effect may result from reduction in the level of parathyroid hormone which regulates the ongoing process of bone remodeling. The maximum positive effect of alcohol consumption on bone was seen in postmenopausal women who ingested >28.6 to 57.2 grams of alcohol per week, about the equivalent of 2-4 mixed drinks, glasses of wine, or cans of beer. The women had 16% greater BMD in the spine, 12% greater total body BMD, and 14% greater forearm BMD than did nondrinking women.

Information on smoking history, past use of estrogen, present use of medications or a history of fractures was adjusted in statistical analysis. Dual X-ray absorptiometry was used to measure BMD at the hip, lumbar spine, whole body, and forearm skeletal sites. Blood levels of several bone marker chemicals and the parathyroid hormone were also obtained. Women identified as moderate drinkers (>28.6 to 57.2 g/wk) were found to have the highest BMD at every skeletal site, though the difference at the hip was not as significant as at the other sites. Serum parathyroid hormone (PTH) was 25-30% lower in moderate drinkers than in nondrinkers.

Serum levels of PTH are the principal determinants of bone remodeling. The significantly lower PTH concentration found in subjects who were moderate drinkers was one cause of a reduction in bone resorption and resultant greater BMD. After adjustments for age at menopause, which occurs about two years later in drinkers than in nondrinkers, a further explanation for the increase in BMD was higher levels of bone formation and estrogen, both of which were stimulated by alcohol.

In an associated editorial, Mukherjee and Sorrell acknowledge the uniqueness of the study's findings, but point out that we are as yet unable to explain why only moderate doses of alcohol have a positive effect on bone density. Until this subject is better understood, it would be premature to recommend alcohol use as a preventative measure for osteoporosis.
-end-
Rapuri, Prema B et al. Alcohol intake and bone metabolism in elderly women. Am J Clin Nut 2000;72:1215-22.

Mukherjeee, Sandeep and Michael F Sorrell. Effects of alcohol consumption on bone metabolism in elderly women. Am J Clin Nut 2000;72:1206-13

For more information please contact: Dr.P B Rapuri at thiyyari@creighton.edu, or mfsorrell@unmc.edu.

This media release is provided by The American Society for Clinical Nutrition, to provide current information on nutrition-related research. This information should not be construed as medical advice. If you have a medical concern, consult your doctor.

To see the complete text of this article, please go to: http://www.faseb.org/ascn/temp/ajcn/November/(11644)rapuri.pdf. To see the complete text of the editorial, please go to: http://www.faseb.org/ascn/temp/ajcn/November/(12135)sorrell.pdf

American Journal of Clinical Nutrition

Related Alcohol Consumption Articles from Brightsurf:

Excessive alcohol consumption during the COVID-19 pandemic
The full impact of COVID-19 on alcohol use is not yet known, but rates have been rising during the first few months of the pandemic.

Alcohol consumption rises sharply during pandemic shutdown
Anecdotal information has suggested that people are buying and consuming more alcohol during the pandemic shutdown.

Associations of alcohol consumption, alcohol-induced passing out with risk of dementia
The risk of future dementia associated with overall alcohol consumption and alcohol-induced loss of consciousness in a population of current drinkers was examined in this observational study with more than 131,000 adults.

Sweet coolers a gateway to increased alcohol consumption
Sweetened alcoholic beverages can promote harmful alcohol consumption among teens, new University of Guelph research finds.

The influence of alcohol consumption among cohabitating partners
Research has linked a partner's or spouse's drinking with changes in alcohol-related behaviors, but few studies have considered only cohabiting relationships.

Does alcohol consumption have an effect on arthritis?
Several previous studies have demonstrated that moderate alcohol consumption is linked with less severe disease and better quality of life in patients with rheumatoid arthritis, but a new Arthritis Care & Research study suggests that this might not be because drinking alcohol is beneficial.

Is alcohol consumption more helpful than harmful? It depends on your age
Studies of health effects of alcohol consumption may underestimate the risks of imbibing, particularly for younger people, according to a new study in the Journal of Studies on Alcohol and Drugs.

Link between alcohol consumption and breast cancer ignored by women most at risk
Middle aged women in Australia aren't getting the message about the proven link between alcohol consumption and breast cancer, at a time when more are drinking while cancer rates in their age bracket are increasing, according to a new study.

How much is too much? Even moderate alcohol consumption is a risk factor for atrial fibrillation
Excessive alcohol consumption is an established risk factor for atrial fibrillation (AF), but what are the effects of moderate and mild consumption on AF?

Moderate consumption of alcohol is associated with fewer hospitalizations
A study of the Department of Epidemiology and Prevention of I.R.C.C.S.

Read More: Alcohol Consumption News and Alcohol Consumption Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.