Nav: Home

Air pollution is associated with cancer mortality beyond lung cancer

October 31, 2017

Air pollution is classified as carcinogenic to humans given its association with lung cancer, but there is little evidence for its association with cancer at other body sites. In a new large-scale prospective study led by the Barcelona Institute of Global Health (ISGlobal), an institution supported by the "la Caixa" Foundation, and the American Cancer Society, researchers observed an association between some air pollutants and mortality from kidney, bladder and colorectal cancer.

The study, published in Environmental Health Perspectives, included more than 600,000 adults in the US who participated in the Cancer Prevention Study II and who were followed for 22 years (from 1982 to 2004). The scientific team examined associations of mortality from cancer at 29 sites with long-term residential exposure to three ambient pollutants: PM2,5, nitrogen dioxide (NO2) and ozone (O3).

Over 43,000 non-lung cancer deaths were registered among the participants. PM2,5was associated with mortality from kidney and bladder cancer, with a 14 and 13% increase, respectively, for each 4.4 μg/m3 increase in exposure. In turn, exposure to NO2 was associated with colorectal cancer death, with a 6% increase per each 6.5 ppb increment. No significant associations were observed with cancer at other sites.

Michelle Turner, ISGlobal researcher and first author of the study, explains that "although a number of studies associate lung cancer with air pollution, there is still little evidence for associations at other cancer sites".

"This research suggests that air pollution was not associated with death from most non lung cancers, but the associations with kidney, bladder and colorectal cancer deserve further investigation" she adds.
-end-
Reference

Ambient Air Pollution and Cancer Mortality in the Cancer Prevention Study II. Turner MC, Krewski D, Diver WR, Pope CA 3rd, Burnett RT, Jerrett M, Marshall JD, Gapstur SM. Environ Health Perspect. 2017 Aug 21;125(8):087013.

Barcelona Institute for Global Health (ISGlobal)

Related Lung Cancer Articles:

'Social smokers' face disproportionate risk of death from lung disease and lung cancer
'Social smokers' are more than twice as likely to die of lung disease and more than eight times as likely to die of lung cancer than non-smokers, according to research presented at the European Respiratory Society International Congress.
Lung cancer therapy may improve outcomes of metastatic brain cancer
A medication commonly used to treat non-small cell lung cancer that has spread, or metastasized, may have benefits for patients with metastatic brain cancers, suggests a new review and analysis led by researchers at St.
Cancer mortality continues steady decline, driven by progress against lung cancer
The cancer death rate declined by 29% from 1991 to 2017, including a 2.2% drop from 2016 to 2017, the largest single-year drop in cancer mortality ever reported.
Cancer-sniffing dogs 97% accurate in identifying lung cancer, according to study in JAOA
The next step will be to further fractionate the samples based on chemical and physical properties, presenting them back to the dogs until the specific biomarkers for each cancer are identified.
Lung transplant patients face elevated lung cancer risk
In an American Journal of Transplantation study, lung cancer risk was increased after lung transplantation, especially in the native (non-transplanted) lung of single lung transplant recipients.
Proposed cancer treatment may boost lung cancer stem cells, study warns
Epigenetic therapies -- targeting enzymes that alter what genes are turned on or off in a cell -- are of growing interest in the cancer field as a way of making a cancer less aggressive or less malignant.
Are you at risk for lung cancer?
This question isn't only for people who've smoked a lot.
Better equipped in the fight against lung cancer
Lung cancer is the third most common type of cancer in Germany and the disease affects both men and women.
New liquid biopsy-based cancer model reveals data on deadly lung cancer
Small cell lung cancer (SCLC) accounts for 14 percent of all lung cancers and is often rapidly resistant to chemotherapy resulting in poor clinical outcomes.
Cancer drug leads to 'drastic decrease' in HIV infection in lung cancer patient
Doctors in France have found the first evidence that a cancer drug may be able to eradicate HIV-infected cells in humans.
More Lung Cancer News and Lung Cancer Current Events

Trending Science News

Current Coronavirus (COVID-19) News

Top Science Podcasts

We have hand picked the top science podcasts of 2020.
Now Playing: TED Radio Hour

Debbie Millman: Designing Our Lives
From prehistoric cave art to today's social media feeds, to design is to be human. This hour, designer Debbie Millman guides us through a world made and remade–and helps us design our own paths.
Now Playing: Science for the People

#574 State of the Heart
This week we focus on heart disease, heart failure, what blood pressure is and why it's bad when it's high. Host Rachelle Saunders talks with physician, clinical researcher, and writer Haider Warraich about his book "State of the Heart: Exploring the History, Science, and Future of Cardiac Disease" and the ails of our hearts.
Now Playing: Radiolab

Insomnia Line
Coronasomnia is a not-so-surprising side-effect of the global pandemic. More and more of us are having trouble falling asleep. We wanted to find a way to get inside that nighttime world, to see why people are awake and what they are thinking about. So what'd Radiolab decide to do?  Open up the phone lines and talk to you. We created an insomnia hotline and on this week's experimental episode, we stayed up all night, taking hundreds of calls, spilling secrets, and at long last, watching the sunrise peek through.   This episode was produced by Lulu Miller with Rachael Cusick, Tracie Hunte, Tobin Low, Sarah Qari, Molly Webster, Pat Walters, Shima Oliaee, and Jonny Moens. Want more Radiolab in your life? Sign up for our newsletter! We share our latest favorites: articles, tv shows, funny Youtube videos, chocolate chip cookie recipes, and more. Support Radiolab by becoming a member today at Radiolab.org/donate.